氨基化合物

In order to achieve salt-free dyeing of cotton fabrics with reactive dyes ,a water-soluble amino-terminated hyperbranched polymer(HBP-NH2) was synthesized from methyl acrylate and diethylene triamine by melt polycondensation.

为了实现棉织物活性染料无盐染色工艺，以丙烯酸甲酯和二乙烯基三胺为原料，采用熔融缩合聚合法合成了1种水溶性端氨基超支化合物(HBP-NH2)。

Furthermore, a series of triterpene glycosides that composed of oleanolic acid, ursolic acid and glucosamine oligosaccharides were synthesized, and their structures were determined.

本文还以具有良好生物活性的五环三萜类的化合物齐墩果酸与熊果酸作为苷元，完成了一系列氨基葡萄糖及其寡糖三萜皂苷的合成和结构确定工作，为测试其生物活性、研究构效关系奠定了基础。

RESULTS: A germacrane sesquiterpenoid, incaspitolide D (1), along with-N-benzoylphenylalanine--2-benzamido-3-phenyl- propyl ester (2), indole-3-carboxylic acid (3), apigenin (4), diosmetin (5) and luteolin (6) was isolated. CONCLUSION: Compounds 1-5 were isolated for the first time from Vernonia patula.

结果：分离到1个牻牛烷型倍半萜内酯， 1个苯丙氨酸衍生物、1个生物碱和3个黄酮化合物，根据波谱数据和X-衍射分析分别鉴定为：incaspitolide D (1)，-N-苯甲酰基苯基丙氨酸–-2-苯甲酰氨基–3-苯基丙酯(S-N-benzoylalanine-–2-benzamido-3-phenylpropyl ester， 2；吲哚-3-羧酸(indole-3-carboxylic acid， 3)；香叶木素(diosmetin， 4)，芹菜素(apigenin， 5)和木犀草素(luteolin， 6)。

The title compound used as an amino acetylating reagent was further reacted to yield Cefepime hydrochloric acid, the crystals obtained has white pale color and is stable to temperature, and has no E-isomer too.

用其作为氨基酰基化试剂进一步合成盐酸头孢吡肟，也得到基本上白色的对温度稳定的不含E-异构体的晶态化合物。

Inletting different substitution amino groups can enhance the antiplatelet aggregation activity of the compounds.

引入不同的取代氨基对哒嗪酮类化合物抗血小板聚集的活性有影响。

Methods: The target compounds were designed and synthesized by inletting different substitution amino groups using acetyl fragment as the connecting segment.Born method was used for preliminary pharmacological test in vitro.

以乙酰基为连接片段，引入不同的取代氨基，设计合成一系列化合物；体外药理实验参考Born方法进行。

In this article,a non-carcinogenic dye intermediate 4-aminodianiline-2-sulfonic acid is synthesized from 4-nitro-1-chlorobenzen through sulfonation,condensation and reduction.

针对联苯胺作为合成染料的重要中间体已被确认为致癌物的情况，以对硝基氯苯为原料，经磺化、缩合、还原，合成了一种无致癌性并取代联苯胺的双胺化合物染料中间体4-氨基二苯胺-2-磺酸，利用红外光谱、差热和氢谱核磁对其性质进行了表征。

The latter is chlorinated in the side chains under free-radical conditions to give 2,4-dichloro-5-fluoro-3-dichloromethyl-1-trichloromethylbenzene. The latter is hydrolysed via 2,4-dichloro-5-fluoro-3-dichloromethylbenzoic acid, which can be isolated if necessary, to give 2,4-dichloro-5-fluoro-3-formyl-benzoic acid, the aldehyde group of which is reacted to give 2,4-dichloro-5-fluoro-3-N-hydroxyiminomethyl-benzoic acid, from which, with simultaneous conversion of the carboxyl group into the chlorocarbonyl group, water is eliminated using an acid chloride to give the nitrile 2,4-dichloro-3-cyano-5-fluoro-benzoyl chloride.

随后，在游离基条件下进行侧链的氯化，得到2，4-二氯-5-氟-3-二氯甲基-1-三氯甲基苯、后者被水解，经过2，4-二氯-5-氟-3-二氯甲基苯甲酸(如果需要此化合物可以分离)，得到2，4-二氯-5-氟-3-甲酰苯甲酸，将其醛基反应，得到2，4-二氯-5-氟-3-N-羟基亚氨基甲基苯甲酸，用酰氯从其中除去水，同时将羧基转化为碳酰氯，得到一种腈，即2，4-二氯-3-氰基-5-氯-苯甲酰氯。

This paper reviews the kinetic mechanism of acetylcholinesterase, illustrates the principle and application of the kinetic parameters such as Michealis-Menten affinity constant Km, maximum reaction velocity Vmax, turnover number Kcat, bimolecular rate constant Ki, affinity constant of the inhibitor for the a ctive site Ka, phosphorylation or carbamylation rate constant K2, and discusses the potential practical application benefiting from the study of the kinetic analysis.

综合评述了AChE的动力学机制的发展状况，着重介绍了米氏常数Km、最大反应速率Vmax、转换率Kcat、双分子速率常数Ki、抑制剂化合物对AChE活性部位的亲和力常数Ka、磷酸化或氨基甲酸化速率常数K2，这些动力学参数的原理及其应用状况，探寻了动力学机制将带来的实际应用。

In this dissertation, the practical significance and the recent development of non-phosgene synthesis of N-substituted carbamates are reviewed briefly, as well as the application of ionic liquids in catalysis.

本论文综述了非光气合成N-取代氨基甲酸酯类化合物的现实意义和研究进展，以及离子液体在催化反应中的应用。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。