氨基化合物

Asymmetric dimethylarginine and monomethyl arginine are endogenously produced amino acids that inhibit all three isoforms of nitric oxide synthase.

点评：内皮一氧化氮以及一氧化氮合酶是目前门静脉高压症以及相关并发症的发病机制的研究热点之一，本文研究了抑制NOS的内源性氨基酸类化合物的清除酶—-二甲基精氨酸–二甲氨基水解酶，进一步的深入探究了这一发病机制，为今后治疗作用位点的选择、药物研发以及相关实验研究提供了一定的理论依据，个人认为该实验意义较大。

Myristic monoethanolamide ammonium sulfatewas synthesized from myristic acid and monoethanolamide with sulfamic acid as sulfating agent .

在芳烃类溶剂与羰基化合物催化剂存在下，以肉豆蔻酸和乙醇胺为原料，氨基磺酸作硫酸化剂，制备了肉豆蔻酸单乙醇酰胺硫酸酯铵盐。

The possibility of 1,4-asymmetric induction in some nucleophilic addition reactions of chiralγ-amino Z-enals 7 with organolithium compounds was investigated.

本文研究了在手性的顺式-γ-氨基-α，β-不饱和醛(7)与有机锂化合物的亲核加成反应中的1，4-不对称诱导效应。

The structure analysis indicates that the reverse symmetry ligand H4LB molecules are linked into a 2D supermolecular network by two types of hydrogen bonds. One type occurs between the oxalamide oxygen group and the phenol hydroxyl qroup of the nearest molecule with d=2.906(2) and ∠O-H…O=151.8°. The other type is between the oxalamide nitrogen group and the oxalamide oxygen group of anther molecule with d=2.849(2),∠N-H…O=158.7°.

晶体结构研究表明配体H4L为顺式桥联分子，晶体中存在两种氢键，一种是草酰胺基团的O原子与苯环上的酚羟基形成O-H…O氢键[d=2.906(2)，∠O-H…O=151.8°]；另一种是草酰胺基团的氨基与相邻草酰胺基上的O原子形成N-H…O氢键[d=2.849(2)，∠N-H…O=158.7°]，通过上述两种氢键将化合物H4LB连接成二维网络结构。

Mehods Commercially available glycine ethyl ester hydrochloride was used as starting material to give the target compound via addition, protection with BOC, Dieckmann cyclation, reduction with NaBH4 and LiAlH4, protection, oxidation, oximation and deprotection.

以甘氨酸乙酯盐酸盐为原料，依次经加成、BOC保护氨基、Dieckmann环化、NaBH4还原羰基、LiAlH4还原氰基、BOC保护氨甲基、氧化、肟化、脱BOC保护等9步反应制得目标化合物。

The results indicated that 3 chemicals could greatly enhance resistance of potato tuber to early blight low concentrations. Protection rates induced by phenol (1mmol/L), benzoic acid (0.01mmol/L), and paraaminobenzoic acid (5mmol/L) were 43.21%, 40.72%, and 28.75%, respectively.

结果表明，供试的3种化合物均在较低浓度下具有较强的诱导抗病作用，苯酚、苯甲酸和对氨基苯甲酸分别在1，0.01和5mmol/L时诱导的保护率最高，分别达到43.21%，40.72%和28.75%，均与对照差异极显著。

Phenol,benzoic acid,and paraaminobenzoic acid,as the elicitors,were evaluated in lab of their efficiences to induce potato tuber against early blight,and the change of resistance related enzymes were investgated in induced potato tuber.

利用苯酚、对氨基苯甲酸和苯甲酸等3种芳香族类化合物作为激发子，对马铃薯块茎抗早疫病的效果进行了探讨，同时分析了诱导处理后马铃薯块茎中与抗病性相关的酶活性的变化。

In order to find highly active pesticide, three series of 5--12-substituent-benzo phenanthridine derivatives were synthesized through the reaction of 2-methylbenzonitrile with dif-ferent aldehyde, and further dehydration with DDQ or N-methylation with NaH and CH3I, respectively.

为了寻找新的高活性农药，利用2-甲基苯甲腈与不同的醛反应，再通过2，3-二氯－5，6-二氰基－1，4-苯醌脱氢或NaH和CH3I氮甲基化，合成了3个系列共18个5-取代氨基－12-取代苯并菲啶衍生物，其中15个是未见文献报道的化合物。

Pyridoxine, pyridoxal , pyridoxamine as well as their phosphated forms are structural analogues in which pyridoxal-5"-phosphate and pyridoxamine-5"- phosphate are the biological active forms in vivo which act as the cofactors of aminotransferases, amino acid decarboxylases, cysteine desufbrase and cystathionine , etc by constant transconversions. Recently, it was discovered that B6 played a novel role in tumor growth suppression.

它包括三种结构十分近似的化合物：吡哆醇(Pyidoxine，PN)、吡哆醛(Pyridoxal，PL)和吡哆胺(Pyridoxamine，PM)，分别以磷酸化的形式发挥作用，其中吡哆醛-5'-磷酸(Pyridoxal-5'-phosphate，PLP)为B_6在体内的活性形式，通过与磷酸吡哆胺(Pyidoxamine-5-phosphate，PMP)的互变，作为多种酶(氨基转移酶、氨基酸脱羧酶、半胱氨酸脱硫酶、胱硫醚酶等)的辅酶而发挥传递基团的作用。

In this paper,the method for synthesis of 5 new phosphonic acid products,from the reactions of 2-amine thiadiazole and different aldehydes with phosphorous acid by the melting method or the solvent method,was introduced.

用2-氨基噻二唑、醛与亚磷酸反应，应用融熔法与溶剂法合成了一系列新的噻二唑膦酸，并用IR、1HNMR、31PNMR等方法对化合物进行了表征。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。