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氨基化合物

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It is composed of three different groups of chemicals, namely cinnamic acid amides, valine amide carbamates and mandelic acid amides.

该类杀菌剂由3组化学结构各不相同的化合物组成,包括肉桂酰胺、缬氨酰胺氨基甲酸酯和扁桃酰胺类。

In these reactions the alkyl and alkyloxy groups in the 4-positions are displaced by the arylamino-group. Since the enzyme tyrosinase exits in melanoma cells and it is uniquely associated with melanocytes, which suggested a highly focused drug delivery system.

基于该反应机理,设计了酪氨酸酶的三个前药模型化合物并进行了体外模型实验,即以酪氨酸酶的底物苯酚和邻氨基苯酚作为药物布洛芬和5—氟脲嘧啶的载体,经酪氨酸酶和亲核试剂的作用,实现药物的释放。

E. value of productions were detected by high performance liquid chromatography. Results The chiral aminoalcohol ligand compound Ⅰ can promote the asymmetric allylation of acylhydrazones and the yield was 57%; The highest values of e. e. obtained for this reaction was 22%.

结果 手性氨基醇配体化合物Ⅰ能够促进烯丙基三氯硅烷和酰腙的烯丙基化加成反应,在它的辅助作用下,烯丙基化加成产物的产率可达到57%,对映体过量值最高达到22%。

Then, D-prolinamide was synthesized by amino protection, esterification, amidation and deprotection.

进一步应用手性源技术,经氨基保护、酯化、氨化和脱保护等步骤,不对称合成目标化合物。

Synthesized three new dithiocarbohydrazones: 1, 5-bis (4-methoxybenzaldehyde) dithiocarbohydrazone (1), 1, 5-bis (p-dimethyl aminobenzaldehyde) dithiocarbohydrazone (2), 1, 5-bis (2-furaldehyde) dithiocarbohydrazone (3), and initially reported the 〓C NMR data of the dithiocarbohydrazones.

合成了3—(谷氨酮—1—基)—4—氨基—5—巯基—1,2,4—均三唑新的中间体化合物,以元素分析,IR,NMR,MS实验技术对其结构进行了表征,研究其NMR波谱特征,并以〓H-〓H COSY,〓C-〓H COSY,COLOC二维NMR技术对其〓H,〓C NMR的谱峰进行了全归属。

Methods Compound 3 was got via the formation of the amide from 2-chloro-3-amino-4-methyl pyridine and 2-chloronicotinoyl chloride, and then nevirapine was acquired by the aminolysis of 3 with cyclopropylamine in an autoclave, followed by the intramolecular nucleophilic substitution.

以2-氯-3-氨基-4-甲基吡啶为原料,依次与2-氯烟酰氯缩合成化合物3、再与环丙胺高压氨解、最后发生分子内亲核取代反应,成功合成了奈韦拉平。

In order to ensure efficient use of the nitrogen source compounds, the metabolic flux of elemental nitrogen was analyzed for L-tryptophan biosynthesis using the 15N anthranilic acid as a tracer in the experimental process.

为了有效的利用含氮的化合物,实验过程中,采用15N标记的邻氨基苯甲酸为示踪剂,分析了N元素在15NL-色氨酸合成过程中的代谢通量。

It was found that the reactions of C_(60) with anthranilic acids and isoamyl nitrite in the presence of triethylamine unexpectedly afforded C_(60)-fusedδ-lactones,which would be difficult to be prepared by other known methods.

通过在三乙胺作用下,富勒烯与邻氨基苯甲酸类化合物和亚硝酸异戊酯的环化反应,首次合成了一系列富勒烯并六元环内酯。

Objective:To study the influence of different amino group introductions on the antiplatelet aggregation activities of pyridazinone derivatives.

目的:研究不同取代氨基侧链的引入对哒嗪酮类化合物抗血小板聚集活性的影响。

Based on the synthesis method and the function of decreasing blood glucose levels of rosiglitazone, and the report on benzoquinones which resulted in a significant decrease in blood glucose levels, a novel non-thiazolidinedione class of PPARy agonist 2, 5-Dihydroxy-3-{4-[2-(methyl- pyridin-2- yl-amino)- ethoxy] -phenyl}-6-phenyl-[l, 4] benzoquinone (4) was designed and synthesized.

在合成罗格列酮的基础上,根据某些醌类结构化合物的类似胰岛素作用,设计并合成了一种非噻唑烷二酮类PPARγ激动剂2,5-二羟基3-{4-[2-(甲基-2-吡啶氨基)-乙氧基]-苯基}-6-苯基-1,4苯醌(4)。

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这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

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