氨基化

ABSTRACT Immobilized penicillin acylase (from E.coli) was used to catalyze 7 phenylacetamido 3 E propenyl cephalosporanic acid hydrolyzation into 7 amino 3 E propenyl cephalosporanic acid. Then, trans APRA was acylated with hydroxyethyl ester of 4 hydroxy D phenylglycine to obtain trans cefprozil.

以7 苯乙酰氨基 3 E 丙烯基 3 头孢菌素 4 羧酸为原料，在青霉素酰化酶作用下，首先酶法水解得到3 E 丙烯基 3 头孢菌素 4 羧酸，过滤固相酶，滤液调pH分离得到反式APRA固体；在青霉素酰化酶作用下，反式APRA再与对羟基苯甘氨酸乙二醇酯缩合，得到反式头孢丙烯；酶法合成所得的产品与进口反式头孢丙烯对照品一致。

The surface hydroxyl group onto magnetic polyvinyl acetate nanoparticles can be obtained by saponification reaction on their surface.

结果表明，磁性聚苯乙烯颗粒与丁二酸酐发生Freidel-Crafts酰基化反应，可以在颗粒表面引入少量羧基；磁性聚甲基丙烯酸甲酯颗粒分别与乙二醇、二缩三乙二醇、聚乙二醇等发生醇-酯交换反应，可以在颗粒表面接枝不同分子链长度的末端羟基；磁性聚醋酸乙烯酯颗粒经过醇解或皂化反应可以获得表面羟基；磁性聚丙烯酸甲酯颗粒通过乙二胺或1，6己二胺的胺解反应可以得到表面氨基，继而与一氯乙酸反应可以引入亚胺二乙酸基团。

Amino to acetyl phenol, in have technology of two kinds of production domestic and internationally, acetic anhydride craft of the United States, acyl changes temperature to have 75 ℃ only, acyl changes mother liquor not apply mechanically, deputy reaction is little, of production thick tasting is kind of white almost, purificatory craft is very simple, activated carbon dosage only 2~3%, the Kun that its product does not have glow material almost in different third alcohol inferior the sealed impurity of amine impurity and minim, settleclear lightness it may not be a bad idea, the product quality that acetic anhydride craft produces is good, but close rate low, cost is high.

对乙酰氨基酚，在国内外有两种生产工艺，美国的醋酐工艺，酰化温度只有75℃，酰化母液不套用，副反应少，生产的粗品几乎是类白色，精制工艺就非常简单，活性炭用量仅2~3%，其产品在异丙醇中几乎无红光物质的醌亚胺杂质及微量的未知杂质，澄明度也好，醋酐工艺生产的产品质量好，但收率低、成本高。

The experimental process was as follows: a set of 5 immobilized copper ion affinity membranes were loaded into a column, uncombined copper ion was removed with 5 mL of sodium phosphate-citric acid buffer (pH 7); the Hb sample volume was 2 mL, and uncombined Hb was eluted with 10 mL of the buffer.

中文内容：摘要：将纤维素滤纸进行碱处理及环氧活化、偶联亚氨基二乙酸、固定化铜离子等处理，并将其装入自制的色谱柱管，制得固定化铜离子亲和膜色谱柱。

E. value of productions were detected by high performance liquid chromatography. Results The chiral aminoalcohol ligand compound Ⅰ can promote the asymmetric allylation of acylhydrazones and the yield was 57%; The highest values of e. e. obtained for this reaction was 22%.

结果 手性氨基醇配体化合物Ⅰ能够促进烯丙基三氯硅烷和酰腙的烯丙基化加成反应，在它的辅助作用下，烯丙基化加成产物的产率可达到57%，对映体过量值最高达到22%。

A series of novel bile acid derivatives as potential hepato-biliary and intestinal scintigraphy imaging SPECT (single photon emission computed tomography) tracers were prepared from bile acids by es-terification, aminolysis of esters and alkylation of amino groups.

以胆酸、鹅去氧胆酸为起始原料，经羧基的酯化、酯的胺解以及氨基的烷基化，合成了一系列潜在的针对肝胆显像和肠显像的SPECT (Single photon emission computed tomography)分子探针前体。

A major proportion of the reaction of some of the aminoplastic resins examined also occurred on ageing,"maturing", of the resin at ambient temperature, this appearing to be an essential phase of the resin preparation process.

热塑性氨基树脂的许多反应都是在树脂储存过程也即是&陈化&过程中发生的，由此可见，树脂的&陈化&对树脂性能的影响很大。

Bis-(4-bromobenzoyl) benzene as the monomer of poly was synthesized by Friedel-Crafts benzoylation reaction. Poly-Ⅱ synthesized via palladium-catalyzed aryl amination reaction using 1, 4-bis-(4-bromo-benzoyl) benzene and 4, 4'-diaminodiphenyl ether as monomers.

通过傅－克酰基化反应合成了1，4-双－（4'-溴苯酰基）苯，以1，4-双－（4'-溴苯酰基）苯和4'4-二氨基二苯醚为单体，通过钯催化的胺基化缩聚反应合成了高性能聚合物－聚亚胺酮－Ⅱ。

Oxo-(4-solanesylaminophenyl)retinoate was successively synthesized from 13-cis-retinoic acid and solanesol by oxidation, bromization and esterification.

以异维A酸和茄尼醇为原料，经氧化、溴化、酯化等一系列反应合成了4-羰基异维A酸(4-N-茄尼基氨基苯酚)酯，其结构经1H NMR，IR和MS表征。

In the third part of this paper, a facile method is presented for synthesis of malonaldehyde dianil from propargyl alcohol by oxidizing using chromium trioxide and addition reaction with aniline.

对肼基苯磺酸是由对氨基苯磺酸经亚硝酸钠重氮化得到的重氮盐用亚硫酸氢钠还原、水解、硫酸酸化制得，本文经多次实验确定了反应原料、用量及反应条件，得到的产品纯度好，产率高。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。