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Methyl-4-aminobenzyl sulfonamide, a key intermediate for synthesis of the pharmaceutical substance Sumatriptan, was prepared throught four steps.

甲基 4 氨基苯甲基磺酰胺是一种重要的医药中间体,主要用于合成药物舒马普坦。

We introduced the sulfonyl group to P-amino alcohols derived from amino acids to prepare β-sulfonamide alcohols.

由于磺酰基的强吸电子作用,磺酰氨基不是作为给电子基团出现,而是和金属钛共同作为Lewis酸对反应起作用的。

OBJECTIVE To obtain the key intermediate of almotriptan ,1-(4-Aminophenylmethane sulfonyl)pyrrolidine.

目的合成得到选择性5-HT1B/1D受体激动剂阿莫曲普坦的关键中间体对氨基苯甲磺酰吡咯烷。

A series of 5-bromopyrimidinyl-containing new sulfonylureas have been synthesized through bromination of 2-amino-4-methyl pyrimidine, followed by further modification and then coupled with sulfonyl isocyanate.

通过2-氨基-4-甲基嘧啶溴代反应以及进一步的衍生、磺酰基异氰酸酯的胺解,合成了一系列含有5-溴嘧啶基的新磺酰脲。

Treatment of 3-amino-4-chlorobenzoic acid with trimethoxymethane generated methyl 3-amino-4-chlorobenzoate in 80.0% yield.2-ethyl pivalate was oxidized by sulfuryl chloride,an...

所得中间体2-乙基特戊酸酯低温下经磺酰氯氧化,与中间体3-氨基-4-氯苯甲酸甲酯反应,所得产物经重排、水解和酰化反应得到目标化合物,总产率25.8%。

Objective To compare effect of the rectal suppository acetaminophenol with oral suspension in febrific children.

目的 比较对乙酰氨基酚直肠栓剂和口服混悬剂对发热患儿的疗效。

Clinicians should be able to recognize and treat significant toxidromes resulting from acetaminophen; anticholinergic agents including antihistamines and psychoactive drugs; anticoagulants such as warfarin or rat poison; cardiac medications including calcium channel blockers, beta-blockers, and digoxin; muscarinic cholinergic agents including carbamates, some mushrooms, and organophosphates; nicotinic cholinergic agents such as insecticides and nicotine; cyanide; ethylene glycol or methanol from antifreeze or rubbing alcohol; iron-containing products such as deferoxamine; opioids such as morphine, hydrocodone, or methadone; salicylate (aspirin-containing products); sulfonylurea; and sympathomimetic agents such as amphetamines, caffeine, cocaine, or ephedrine.

医师必须可以辨识与治疗乙醯胺酚;抗胆碱剂,如抗组织胺与精神作用药物;抗凝血剂,如warfarin或杀鼠剂;钙离子阻断剂、乙型阻断剂、毛地黄等心脏药物;蕈毒胆碱剂,如氨基甲酸酯盐、某些有毒蘑菇、有机磷农药;菸碱性胆碱剂,如杀虫剂与尼古丁;氰化物;抗冻剂或外用酒精的乙二醇或者甲醇;含铁产品,如 deferoxamine;鸦片类,如吗啡、hydrocodone、美沙冬;水阳酸;硫醯基尿素类降血糖药;拟交感神经药物,如安非他命、咖啡因、古柯碱或麻黄素等造成的明显中毒症候群。

The interaction between tRNA and aminoacyl-tRNA synthetase play an important role in life process.

tRNA与氨基酰tRNA合成酶在蛋白质生物合成及其它生命过程中起重要作用。

Aminoacyl-tRNA synthetase is a class of ancient proteins, catalyzing the first reaction of protein biosynthesis.

氨基酰-tRNA合成酶是一类古老的蛋白质,催化蛋白质生物合成中的第一步反应。

To develop an eco-friendly epoxy impregnating resin system for groundwall insulation of large generators, the curing reaction mechanism has been fully studied, the formulation and the curing techniques have been optimized, and the influence of different constitution on the curing reaction, microstructure, and final performances have been studied and characterized.In this paper, influences of different reactive organo-siloxanes on the curing reaction and performances of epoxy V.P.I.

本文研究比较了含有环氧基、氨基或乙烯基的反应性硅氧烷,包括:γ-缩水甘油醚氧丙基甲基二乙氧基硅烷、β-(3,4环氧环已基)乙基三乙氧基硅烷、γ-缩水甘油醚氧丙基三甲氧基硅、β-(3,4环氧环已基)乙基三甲氧基硅烷、γ-甲基丙烯酰氧基丙基三甲氧基硅烷、乙烯基三乙氧基硅烷和苯胺甲基三乙氧基硅烷对环氧V.P.I。

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