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氨化合物

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Employing CuI(5 mol%), N,N-dimethylglycine hydrochloride(10 mol%) and K_2CO_3(2 equiv.) in refluxing THF as the optimized reaction conditions,the four-membered 4-alkylidene-2-azatidinones could be efficiently synthesized.

当以3-溴-3-N-苯基-丁烯酰胺为底物,在5 mol%CuI为催化剂,10 mol%N,N-二甲基甘氨酸盐酸盐为配体,2当量K_2CO_3作碱,THF回流的反应条件下,可以高效的合成2-亚甲基-4-氮杂环丁酮类化合物。

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