氧氢基

The thesis aims at the studies on the synthesis of dihydroagarofuransesquiterpenes and the synthesis of the important intermediates —α-methoxylmethyl butenolide and α-methoxyl-methyl butadienolide in the synthetic approachto Germacranolide sesquiterpenes from α--Santonin.Ⅰ.

本论文以α--山道年为原料，对二氢沉香呋喃倍半萜的合成以及吉马型倍半萜合成中的重要中间体12-甲氧基-7(11)-烯-6，13-内酯及12-甲氧基-5(6)，7(11)-二烯-6，13-内酯的合成进行了研究。

These chemical shifts in the aromatic region of the resulting nucleophilic adduct 2-F were consistent with the counterparts of 9,10-dihydro-9-methoxy-9-(4-methoxyphenyl)-10-methylacridine, 17b which was proven to be the adduct of the 9-phenyl acridinium salt formed with an excess of MeOH (Figure S7 in Supporting Information).

在最终的亲核加成化合物2-F的芳香族区中的这些化学位移与9，10二氢-9-甲氧基-9-(4甲氧基苯基)-10-甲基吖啶的对应物是一致的，17b 这被证明是与过量的MeOH形成的9-苯基吖啶盐的加成化合物（支持信息中的图S7）。

Till today, we have extracted and purified alkaloids from from Macleaya Cordata, Chelidonium Majus L., Tripterygium Wilfordii Hook f., Sedum Sarmentosum Bunge, and obtained pure sanguinarine, ethoxysanguinarine, oxysanguinarine, chelidonine, chelerythrine, ethoxychelerythrine, chelilutine, chelirubine, protopine,α-allocryptopine,β-allocryptopine, coptisine, berberine, corysamine, bocconine; triptolide, tripdiolide, triptonide, wilforddine; N-methylisopelletierine, dihydro-N-methylisopelletierine, sarmentosin etc.

我们对博落回、白屈菜、雷公藤、垂盘草等天然植物进行了大量的提取和分离研究；并分离出了血根碱、乙氧基血根碱、氧化血根碱、白屈菜碱、白屈菜红碱、乙氧基白屈菜红碱、白屈菜黄碱、白屈菜玉红碱、原阿片碱、α-别隐品碱、β-别隐品碱、黄连碱、小檗碱、沙明碱、博落回碱，雷公藤内酯醇、雷公藤内酯二醇、雷公藤内酯酮、雷公藤碱，N-甲基异石榴皮碱、二氢- N-甲基异石榴皮碱、垂盘草甙等单体。

Bis vinyl phenyl terminated polydimethylsiloxane was synthesized by the hydrosilylation of bis dimethylhydrogen siloxyl terminated PDMS with m divinyl benzene. The structure of the VTPDMS was characterized by 1H NMR.

通过双二甲基氢硅氧封端的聚二甲基硅氧烷与间二乙烯基苯的硅氢加成反应制备了双乙烯基苯封端的聚二甲基硅氧烷，用1H NMR对其结构进行了表征。

The results of in situ DRIFTS on propylene oxidation show that the allyl species originated from α-H abstraction of propylene were located at the wavenumbers of 1454 cm~(-1) and 1427 cm~(-1). The rate-determining step is the abstraction of an α-H abstraction from a lattice oxygen linked to a bismuth ion to form a π-allyl intermediate coordinated to a molybdenum ion. The metal-oxo group then attacks the allyl intermediate forming a σ-bonded oxygen-allyl species, which is in a rapid equilibrium with the π- bonded species. The σ-bonded species then transforms to acrolein by further abstraction of α-H. Such species as formate, carboxylate, carbonate transform to deep oxidation products. The acetone was derived from propylene by an enolic species at lower temperatures.

丙烯氧化反应体系的原位漫反射红外光谱研究结果表明，由丙烯脱氢生成的烯丙基中间物种吸收峰在1454cm~(-1)和1427cm~(-1)处；基于此提出了较完整的丙烯氧化反应网络：丙烯选择氧化生成丙烯醛主要经历丙烯脱除甲基上的一个H，生成烯丙基物种，该物种嵌氧生成σ-O络合物，脱氢得到丙烯醛前驱体，脱附生成丙烯醛；完全氧化产物是由催化剂表面上生成甲酸盐、羧酸盐、碳酸盐等形式的中间物种转化而成；较低反应温度下丙烯氧化生成丙酮，通过烯醇式中间物种氧化生成丙酮前驱体得到。

In the presence of alkalinity and tetraethyl ammonium bromide, 2,4-dihydroxy benzophenone reacts with allyl glycidyl ether to form an ethylenic derivative of benzophenone, 2-hydroxy-4-(β-hydroxy-γ-allyloxy) propyloxy benzophenone, which can further undergo hydrosilylation with polyhydromethylsiloxane.

在相转移催化剂四乙基溴化按作用下，利用2，4-二羟基二苯甲酮与烯丙基缩水甘油醚在碱性水溶液中的开环加成反应，合成了中间体4-丙氧基－2-羟基二苯甲酮，将其进一步与聚甲基氢硅氧烷进行硅氢化加成反应。

The process comprises the subsequent steps a through e: a reacting phthalic anhydride with fluorobenzene or a derivative thereof in appropriate reaction conditions; b over reducing the product obtained in step a at the ketone moiety; c reducing the product obtained in step b with sodium dihydro-bis (2- 15 methoxyethoxy) aluminate to the corresponding alcohol ; d chlorinat ing the alcohol obtained in step c ; e inserting CO into the product obtained in step d through an appropriate Pd-containing catalytic system.

该方法包括以下步骤a～e：a使邻苯二甲酸酐与氟苯或者其衍生物在适当的反应条件中反应；b完全还原步骤a中获得的产品的酮部分；c用二氢-二(2-甲氧基乙氧基)铝酸钠将步骤b中获得的产品还原成相应的醇；d对步骤c中获得的醇进行氯化；e通过适当的含Pd的催化剂体系，将CO插入到步骤d中获得的产品中。

Methods 2-(piperazin-1-yl)-1-(pyrrolidin-1-yl)ethanone (2) was synthesized from pyrrolidine via amidation and substitution, followed by treating with chloroacetyl chloride and triphenylphosphine in a "one pot" manner to give the corresponding phosphonium chloride 3 in a stable and pure form after crystallization from isopropanol.

以四氢吡咯为原料，先与氯乙酰氯成酰胺，再与哌嗪发生取代反应制得中间体［（1-四氢吡咯基）甲基］哌嗪(2)；化合物2与氯乙酰氯和三苯基膦反应，经异丙醇重结晶得到稳定的有机鏻盐(3)；化合物3与3，4，5-三甲氧基苯甲醛发生Wittig反应，再与马来酸成盐得目标化合物马来酸桂哌齐特(1)。

The result of potassium malonyloxyborohydride as a new hydroboration reagent reacts with terminal alkenes and alkynes is described.

介绍新的硼氢化试剂丙二酰氧基硼氢化钾与链端烯炔烃的作用，烯烃的硼氢化物在PTC条件下，插入∶CCl2 ，可得饱和羧酸；炔烃则难以与之硼氢化。

Malonyloxyborohydride,a hydroboration reagent,is prepared by reaction of malonic acid and sodium borohydride,and is used to react with dihydromyrcene in THF.

用一种硼氢化试剂———丙二酸与硼氢化钠反应生成的丙二酰氧基硼氢化钠在THF中与二氢月桂烯反应制备香茅醇。

This one mode pays close attention to network credence foundation of the businessman very much.

这一模式非常关注商人的网络信用基础。

Cell morphology of bacterial ghost of Pasteurella multocida was observed by scanning electron microscopy and inactivation ratio was estimated by CFU analysi.

扫描电镜观察多杀性巴氏杆菌细菌幽灵和菌落形成单位评价遗传灭活率。