氧

The machine applies Faraday magnetic conductivity principle for the first time, utilizes the difference between oxygen of air andnitrogen, paramagnetism of oxygen and diamagnetism of nitrogen principles and adopted high-performance rare-earth permanent-magnet material, which creates 18 proprietary technologies that take polyoxier and helimagnetizer as core.

该机首次应用法拉弟导磁性原理，利用空气中氧、氮磁性之差，即氧的顺磁性和氮的抗磁性原理。采用高性能稀土永磁材料，创造了以"聚氧器"和"螺旋磁化器"为核心的16项专有技术。聚氧器利用氧的顺磁性，采用高梯度强磁场富聚空气中的氧，同时设有与离心叶轮同步高速旋转的双向扫射磁场，对富聚的氧予以充分的激活。

Methods Starting from 2-chloro-4-nitrophenol and 2- pyridine hydrochlorid, 3-chloro-4-(pyridin-2-ylmethoxy) aniline was obtained via etherization and reduction. The obtained aniline coupled with N-(4-chloro-3-cyano-7-ethoxyquinolin-6-yl) acetamide to give 4-[3-chloro-4-(2-pyridylmethoxy) phenylamino]-3-cyano-7-ethoxy-6-N-acetylaminoquinoline. And then it was deacetylated, followed by reacting with4- but-2-enoyl chloride to yield the target compound neratinib.

以2-氯－4-硝基苯酚和2-氯甲基吡啶为起始原料，经醚化、硝基还原得到3-氯－4-（吡啶－2-甲氧基）苯胺，3-氯－4-（吡啶－2-甲氧基）苯胺与3-氰基－6-乙酰氨基－7-乙氧基－4-氯喹啉反应得到3-氰基－6-乙酰氨基－4-［3-氯－4-（吡啶－2-甲氧基）苯氨基］－7-乙氧基喹啉，3-氰基－6-乙酰氨基－4-［3-氯－4-（吡啶－2-甲氧基）苯氨基］－7-乙氧基喹啉去乙酰保护基后，与-4-二甲氨基－2-丁烯酰氯经酰化反应得到ner-atinib。

They are 4-(2- hydroxy-3-butynlenoxy) benzoic acid (1, WA), 5-chloro-7, 8-dihydroxy-7-methyl- 6-oxo-3- [ -3, 4-dihydroxy-3, 5-dimethyl-l-heptylene] -1H-8, 8a-dihydrobenzo [2, 3-c] pyran (2, WB),-2-(2-methyl-2-dibutene diamido)-2-butenoic acid (3, B5262), 3, 4-dihydro-9, 10-dihydroxy-7-methoxy-3-methyl-1H-naphtho [2, 3- c] pyran-1-one (4, A73 semi-Vioxanthin), 8, 8'-bis (6, 9-dioxo-3,4-dihydro-10- hydroxy-7-methoxy-3-methyl-1H-naphtho [2, 3-c] pyran-1-one)(5, A122 Xanthomegnin), 2, 5-dioxo-3a-hydroxymethyl-3, 3a, 6, 6a-tetrahydro-furo [2, 3-b] furan (6, 1003-2), 7-acety1-5-chloro-6, 8-dioxo-7-methyl-3- [ -3, 5-dimethyl-1, 3- diheptylene] -4aH-benzo [2, 3-c] pyran (7, M2-2 sclerotiorin), respectively.

它们分别被命名为4-（2-羟基-3-丁炔氧基）苯甲酸（1，WA）、5-氯-7，8-二羟基-7-甲基-6-氧代-3-[-3，4-二羟基-3，5-二甲基-1-庚烯基]-1H-8，8a-二氢苯并[2，3-c]吡喃（2，WB）、-2-（2-甲基-2-丁烯二酰亚胺基）-2-丁烯酸（3，B5262）、3，4-氢-9，10-二羟基-7-甲氧基-3-甲基-1H-萘并［2，3-c］吡喃-1-酮（semi-Vioxanthin，4，A73）、8，8'-双（6，9-二氧代-3，4-二氢-10-羟基-7-甲氧基-3-甲基-1H-萘并［2，3-c］吡喃-1-酮）（Xanthomegnin，5，A122）、2，5-二氧代-3a-羟甲基-3，3a，6，6a-四氢-呋喃并［2，3-b］呋喃（6，1003-2），7-乙酰基-5-氯-6，8-二氧代-7-甲基-3-［-3，5-二甲基-1，3-庚二烯基］-4aH-苯并2，3-c］吡喃（Sclerotiorin，7，M2-2）。

By means of GPC,IR,GC-MS,~(13)CNMR,~1HNMR,Methylation analysisetc,structural properties of PST-1 were identified as follows:The Mwof PST-1 was 3.44×10~6 Da and its optical rotation was _D~(20)=+0.110°(c0.1, H_2O); PST-1 constituted 8 simple sugars and the molar ratio was 2,4-Dimethoxy-Mannose:Rhamnose:Ara-binose:Xylose:Galactose:D-Galacturonic acid:Mannose:D-glucuronic acid=2%:5%:24%:9%:3%:1%:46%:10%;The chief bone of PST-1 was 1,3,6-linked-β-D-Man residue and the side chains contained Furanoid and Pyranoid residues.

结合GPC、旋光度测定、IR、GC-MS、~(13)CNMR、~1HNMR、高碘酸氧化法、Smith降解以及甲基化方法等分析测试方法，得到PST-1的单糖组成及结构表征，实验结果如下：红豆杉多糖PST-1是重均分子量为3.44×10~6 Da的支链多糖，旋光度为20D=+0.110~0(c0.1，H_2O)；PST-1单糖组成为：2，4-Dimethoxy-Mannose：Rhamnose：Arabinose：Xylose：Galactose：D-Galacturonic acid：Mannose：D-glucuronic acid=2％：5％：24％：9％：3％：1％：46％：10％；PST-1的骨架结构为：具有1，3，6-连接的β-D-甘露糖残基骨架，侧链分枝包括非还原末端的呋喃型α-L-阿拉伯糖残基、吡喃型α-L-阿拉伯糖残基、β-D-木糖残基、β-D-甘露糖残基、2，4-二氧甲基-β-D-甘露糖残基和α-D-葡萄糖醛酸残基；侧链的糖残基也可能存在2，5-二氧-取代呋喃型α-L-阿拉伯糖基、3-氧-取代的β-D-木糖残基、6-氧-取代的α-D-半乳糖醛酸残基、6-氧-取代的α-D-半乳糖残基、4-氧-取代的α-D-葡萄糖醛酸残基和2-氧-取代的α-L-鼠李糖残基，同时后者也可能穿插在主链上。

The preparation of avermyctin emulsions in water was achieved by mixing the surfactants polyoxyethylene (10) octylphenyl ether (OP10), polyoxyethylene styrenated phenol ether (602), and polyoxyethylene (40) castor oil ether (EL-40) with polyoxyethylene (20) castor oil ether (EL-20), separatively. Emulsion stability was investigated by analyzing the hydrophile-lipophile balance, critical micelle concentration, and surface tension. Then, the surfactants of polyoxyethylene polyoxypropylene styrenated phenol ether (1601), block copolymer (L64), and octyl phenyl polyoxyethylene phosphonate were added to the emulsion made by blending EL-40 and EL-20, separatively. The stability of the emulsions was investigated further and discussed in terms of droplet size, surface tension, and zeta potential.

首先将辛基酚聚氧乙烯醚(OP10)、苯乙烯基酚聚氧乙烯醚(602)和蓖麻油聚氧乙烯(40)醚(EL-40)分别与蓖麻油聚氧乙烯(20)醚(EL-20)复配制备阿维菌素水乳剂，从亲水亲油平衡值、临界胶束浓度、表面张力等方面分析了二元表面活性剂复配对乳液稳定性的影响；其次，在EL-40与EL-20复配基础上，将苯乙烯基酚聚氧乙烯聚氧丙烯醚(1601)，嵌段共聚物(L64)和辛基酚聚氧乙烯醚磷酸酯分别添加到乳液中，从粒径、表面张力和zeta电势等方面考察三元表面活性剂复配对乳液稳定性的影响。

Objective:Observes the babies and infants use nasal cannulae or changed two-sided hole pipe attracts the oxygen effect,to evaluate the nasal cannulae and the changed two-sided hole pipe attracts the oxygen to the babies and infants oxygen treatment effect is whether same.

目的：观察婴幼儿双孔吸氧管吸氧和改良双侧孔导管吸氧效果，评价双孔吸氧管吸氧和改良双侧孔导管吸氧法对婴幼儿氧疗效果是否相同。

The observed EMF values of oxygen concentration cell coincided withtheoretical values perfectly, indicating that the ceramics were purely oxide-ionicconductors with oxygen ion transference number of 1 under oxygen atmosphere over thewhole temperature range. The electrochemical oxygen permeation rates determined were inaccordance with the theoretical rates calculated from Faradays law, verifying directexperimentally that the oxide-ionic nature of the conduction under oxygen atmosphere. Athigh oxygen partialpressure range pO_2=10~(-5～10~5 Pa, they were almost pure ionicconductors, which was consistent with the result by means of oxygen concentration cell.Whereas at low oxygen partial pressure range pO_2=10~(-5～10~(-15)Pa, the samplesexhibited mixed ionic and electronic conduction.

结果表明，氧浓差电池电动势的实测值与理论值吻合得很好，氧离子迁移数为1，表明该系列样品在该温度下氧气气氛中为纯氧离子导体；氧泵实验结果进一步证实了该系列样品在氧气气氛中为纯氧离子导体；在氧分压pO_2=10~(-5)～10~5 Pa的高氧分压气氛中，电导率与氧分压变化基本无关，表明在该氧分压范围样品为纯离子导体，这与氧浓差电池电动势测定结果相吻合：在低氧分压为10~(-5)～10~(-15) Pa范围，总电导率随氧分压降低而稍有升高，表明在该氧分压范围样品为氧离子与电子的混合导体。

In chapter three the performance and structure of components of oxygen probe were especially investigated. The Cr-Cr〓O〓 powder was overcome by treatments. The reason of occurrence of thermal peaks on the EMF curves was explained. A water glass based cement which high temperature insulation was around 10MΩ within 10 seconds at 1600℃ was developed for the use of oxygen probe. The effects of tip end thickness of ZrO〓 tube and amount of reference electrode on response time and thermal equilibrium in oxygen probe were investigated. The optimum tip end thickness of ZrO〓 tube and amount of reference electrode addition were determined. It is found that the heat transfer in oxygen galvanic cell is the rate limiting-step in the response process. The national oxygen probe WOS Ⅱ type was designed and manufactured. By three batches of industrial tests its specification reached the level of American Celox Ⅱ type oxygen probe.

在第三章中分别从参比电极、高温绝缘水泥、插接件等组元入手，着重分析了其性能和结构，开发出了适合于钢液定氧用的Cr-Cr〓O〓参比电极，解决了Cr-Cr〓O〓参比电极高温产生收缩问题，解释了电动势曲线产生峰值的原因；开发了适合于定氧测头使用的水玻璃基耐火水泥，其高温绝缘电阻在1600℃，10秒以内为10MΩ左右；同时对ZrO〓管头部厚度、参比电极量对响应时间的影响以及定氧测头中的热平衡进行了研究，得出了合适的ZrO〓管头部厚度和参比电极加入量，确定了氧浓差电池中的传热是响应过程的限速步骤；设计制造了国产WOSⅡ型定氧测头，进行了三次现场定氧测试，其技术指标达到了美国Celox型定氧测头的水平。

The results indicated that, when dissolved oxygen concentration varied from 6 mg/L to 9 mg/L, turbots in nano-metre pure oxygen system were higher on growth, survival rate and feed conversion efficiency than those of air system; A farming trial was conducted to determine growth difference of turbot between pure oxygen and air system. Length growth, weight growth, survival rate and FCE were better in nano-metre pure oxygen system than air system. The results suggested that nano-metre pure oxygen was better than aeration in turbot farming system when dissolved oxygen concentration was from 6~9 mg/L.

结果表明，微米纯氧Ⅰ组大菱鲆的体重增长、成活率、肥满度及饵料转化率高于机械增氧组；微米纯氧Ⅱ组各指标低于机械增氧组。7个月的大规模生产试验（800 m2水面，溶解氧6~9 mg/L）表明，采用微米纯氧气泡增氧养殖大菱鲆，各测定指标均显著高于机械增氧，可以加快大菱鲆生长，提高成活率和饵料转化率。

Complexes 7-12, 16, 22 and 23 are dimeric molybdatesor dimeric tungstates, the central metal with citrate or malate in a molar ratio of 1:1. Theanions of these complexes have two metal atoms and two ligands. Each ligand acts as atridentate fashion via theirα-alkoxy,α-carboxy andβ-carboxy groups coordinated to eachmetal atom. Complex 13 is a monomeric molybdate. The citrate ligand coordinates tomolybdenum with itsα-alkoxy,α-carboxy andβ-carboxy groups in a tridentate mode.

其配阴离子中都含有2个金属原子和2个配体，且配体均以α-烷氧基、α-羧基和β-羧基氧与中心金属三齿配位。13是单核柠檬酸钼配合物，柠檬酸也以α-烷氧基、α-羧基和β-羧基氧与钼三齿配位。17和21分别为苹果酸钼、柠檬酸钨单核配合物，其中苹果酸、柠檬酸配体均以α-烷氧基氧和α-羧基氧与金属双齿配位。

This one mode pays close attention to network credence foundation of the businessman very much.

这一模式非常关注商人的网络信用基础。

Cell morphology of bacterial ghost of Pasteurella multocida was observed by scanning electron microscopy and inactivation ratio was estimated by CFU analysi.

扫描电镜观察多杀性巴氏杆菌细菌幽灵和菌落形成单位评价遗传灭活率。