氟化反应

The effects of substituents on the nucleophilic reaction of benzyl halide and sodium azide were studied.

合成了叠氮苄、对氰基叠氮苄，对氟叠氮苄，对甲基叠氮苄和联苯二叠氮苄，研究了苯环上不同取代基对苄基卤代物与叠氮化钠经亲核取代反应生成苄基叠氮化物的反应的影响。

The paper discusses the process conditions of producing synthetic cryolite by carbonation method and the main factors affecting the yield rate of sodium fluosilicate.

本文探讨了碳酸化法合成冰晶石的工艺条件，确定了影响氟硅酸钠纯碱分解率的主要因素，试验结果表明：NaF溶液的精制和〔6F-〕/〔Al〕、反应温度等对冰晶石性能有显著的影响。

In the arylation reaction, the temperature was meliorated from -40℃ to -15℃, which could be easy controlled with ice-salt bath. Furthermore, the reaction could be carried out reposefully by adding the initiator.

其中在以2，5-二氟溴苯格氏试剂进行芳基化反应时，改进了反应条件，克服了文献使用的低温条件(-40℃)，简便了操作，同时通过加入合适的引发剂，使反应能够平稳进行。

Synthesis of the substance from aniline and hexafluoroacetone involves electrophilic addition ,acylation and reduction.

其合成一般是以苯胺和六氟丙酮为起始原料，经过亲电加成、酰化和还原三步反应。

The principle of preparation for white carbon black is described, the influence of the concentration of fluosilicic acid, the dripping velocity of ammonia water, the reaction temperature and the curing time on the specific surface area of white carbon black are studied.

论述了白炭黑的制备原理，研究了氟硅酸浓度，氨水滴加速率，反应温度，陈化时间对白炭黑比表面积的影响。

Methods 4-Hydroxy- benzonitrile was treated with sodium hydrogen sulfide and anhydrous magnesium chloride in dimethyl formamide to give thioamide, which was then directly cyclized with ethyl 2-chloroacetoacetate without separation to give ethyl 2-(4-hydroxyphenyl)-4-methylthiazole-5-carboxylate(2) in one-pot; then 2 was formylated with Duff reaction adopting hexamethylenetetramine in trifluoroacetic acid to give ethyl 2-(3-formyl-4-hydroxyphenyl)-4-methylthiazole-5-carboxylate(3); finally, the target compound was obtained by the treatment of 3 with hydroxylamine hydrochloride and sodium formate in formic acid.

采用&一勺烩&方法，以4-羟基苯甲腈为起始原料，首先与硫氢化钠和无水氯化镁在N，N-二甲基甲酰胺中反应，所得中间体不经分离，直接加入2-氯乙酰乙酸乙酯进行环合反应，得到2-(4-羟基)苯基-4-甲基-5-噻唑甲酸乙酯（2）；然后通过六亚甲基四胺/三氟乙酸进行Duff反应，得到2-(3-甲酰基-4-羟基)苯基-4-甲基-5-噻唑甲酸乙酯（3）；再经盐酸羟胺/甲酸/甲酸钠体系脱水得到目标化合物。

A new convenient synthesis of a series of 1-aryl-2-propanones using aromatic amine s as precursors, via diazo reaction and improved Meerwein arylation reaction under mild conditions, was achieved.

以芳香胺为原料，经重氮化和改进的Meerwein芳基取代反应，合成了一系列的1-芳基-2-丙酮，其中1-(3，5-二三氟甲基苯基)-2-丙酮是一个新化合物。

A new convenient synthesis of a series of 1-aryl-2-propanones using aromatic amines as precursors, via diazo reaction and improved Meerwein arylation reaction under mild conditions, was achieved. In addition, 1-[3,5-bisphenyl]-2-propanone is a new compound among the synthesized compounds. This approach is an efficient synthetic method for the aryl-propanones with the different substituting groups.

以芳香胺为原料，经重氮化和改进的Meerwein芳基取代反应，合成了一系列的1-芳基－2-丙酮，其中1-（3，5-二三氟甲基苯基）2-丙酮是一个新化合物改进后的方法简化了合成步骤，提高了收率，可方便地用于在苯环上具有不同取代基的芳基丙酮的合成。

Bis(4-fluorophenyl)phenyl phosphine oxide was synthesized by Grignard reaction, and sulfonated bis(4-fluorophenyl)phenyl phosphine oxide was prepared by sulfonation of BFPPO.

具体内容如下：通过Grignard反应合成了二(4-氟苯基)苯基氧膦单体，并将其磺化，合成了二(4-卤苯基)-3-磺酸钠苯基氧膦单体。

METHODS Dinitrofluorobenzene was used to induce the contact dermatitis in mouse ear, rhIL-11 0.375-1.5 mgkg^(-1)d^(-1) sc for 10 d, the degree of skin inflammatory reaction was observed. At the same time, the serum level of tumor necrosis factor-α and interleukin-6(IL-6) was measured by radioimmunoassay; the serum level of nitrogen monoxidum was detected by biochemical method and the expression of intercellular adhesion molecule-1(ICAM-1) was detected by immunohistochemical method.

采用2，4-二硝基氟苯致小鼠耳部皮肤接触性皮炎试验模型，观察sc rhIL-11 0.375~1.5mgkg^(-1)d^(-1)，连续10d后皮肤炎症反应程度，同时采用放射免疫分析法测定血清中肿瘤坏死因子-α和白细胞介素-6(IL-6)的水平，采用生物化学检测法测定血清一氧化氮的水平，采用免疫组化法测定皮肤中细胞间粘附分子(ICAM-1)的表达。

Singer Leona Lewis and former Led Zeppelin guitarist Jimmy Page emerged as the bus transformed into a grass-covered carnival float, and the pair combined for a rendition of "Whole Lotta Love".

歌手leona刘易斯和前率领的飞艇的吉他手吉米页出现巴士转化为基层所涵盖的嘉年华花车，和一双合并为一移交&整个lotta爱&。

This is Kate, and that's Erin.

这是凯特，那个是爱朗。