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氟化作用

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Both CaCN2 and urea inhibited the chlamydospore germination, mycelial growth and sporulation of the pathogen, but CaCN2 by using at the rates of 0.5 and 1.0%, had two inhibition zones for chlamydospore germination with time while urea had only one. Calcium cyanamide was also more effective on reducing mycelial growth and sporulation of the pathogen than urea did. Therefore, the suppression of pea wilt might be due to fungicidal effect of the intermediate products including hydrogen cyanamide and urea from calcium cyanamide.

由氰氮化钙(0.5及1.0%处理者)之抑制曲线在不同的时间出现两个抑制区,而尿素则仅有一个,及氰氮化钙对萎凋病菌菌丝生长及产胞的影响远较尿素为甚,显示氰氮化钙之所以能有效抑制萎凋病的主要因子,或许是来自其中间产物,包括尿素及氟酸的杀菌作用。

The application of fluor protector can restrain enamel demineralization and promote enamel remineralization.

氟漆的应用有明显抑制牙釉质脱矿及促进再矿化的作用。

In part one, the reactions of some active fluorine-containing compounds such as 2, 2-dihydropolyfluoroalkanoic acids and ethyl 2-hydropolyfluoroalkenoates were studied and various fluorine-containing heterocyclic compounds were synthesized. Using 2, 2-dihydropolyfluoroalkanoic acids as the starting material, 4-fluoroalkyl quinolin-2-ols, 2- [ -1-hydropolyfluoro-1-alkenyl] -4H-3, 1-benzoxazin-4-ones, 1-aryl -4, 9-dihydro-3-fluoro-alkyl-1H-pyrazo [3, 4-b] quinolin-4-ones, 5-fluoroalkyl-12H-quin olino [2, 1-b] quinazolin-12-ones, 4-fluoroalkyl-1, 3-dihydro-1, 5-benzodiazepin-2-ones and 4-fluoroalkyl-2H-pyrido [1, 2-a] pyrimidin-2-ones were synthesized through its condensation reaction with anilines, anthranilic acid, N'-aryl-o-aminobenzamides, o-nitro aniline, o-amino pyridine and their derivatives and the subsequent transformations. 5-Fluoroalkyl isoxazolidines, 3-fluoro-3-fluoroalkylisoxazolidino [4, 3-c] quinolin-4-ones, 3-fluoroalkylisoxazolino [4, 3-c] quinolin-4-ones and 2-aryl-3per fluoroacylindoles were synthesized by inter-and intramolecular 1, 3-dipolar cycloaddition of fluorine-containing olefins and nitrones.

第二部分,我们研究了α,α-二氟苄基卤类化合物的亚磺化脱卤反应、产物的转化及全氟烷基亚磺酸盐与芳环化合物的全氟烷基化反应,发现全氟苄基碘或溴及α,α一二氟苄基溴在保险粉等亚磺化脱卤试剂引发下可生成相应的亚磺酸盐;全氟苄基亚磺酸盐与氯气或溴反应可生成全氟苄基磺酰氯或磺酰溴;在烯烃存在下,全氟苄基碘则与烯烃发生加成反应,生成相应的1:1加成产物;在三价醋酸锰的作用下,部分芳香化合物如茴香醚,二甲氧基苯,吡啶,喹啉等可以和过量的全氟烷基亚磺酸盐发生双全氟烷基化反应,反应表现出一定的区域选择性,产率良好。

A process for preparingp-fluo-2-(2-methyl-3-propionyl)-4-oxy-N,3-diphenyl-phenylbutylamide includes such steps as Friedle-Craft acylating of newly prepared phenylacetyl chloride and fluorobenzene under catalysis of AlCl3 to obtain 4-fluoro-phenylbenzyl ketone, brominating at carbonyl alpha position under catalysis of less AlCl3 to obtain alpha-bromo-4-fluo-phenylbenzyl ketone, and condensing with isobutyryl acetanilide under action of sodium ethoxide.

本发明涉及一种制备对氟-2-(2-甲基-3-氧丙基)-4-氧-N,3-二苯基-苯丁酰胺(1)的方法,其包括以下步骤:新制的苯乙酰氯与氟苯在AlCl3催化下进行Friedle-Craft酰化反应,得到对4-氟-苯基苄基酮(4);化合物(4)在少量AlCl3催化下进行羰基α位溴化,得到α-溴-4-氟-苯基苄基酮(5);然后(3)异丁酰乙酰苯胺在乙醇钠作用下与化合物(5)进行缩合。

On experimental day , the rats were intratracheally instilled with bleomycin(5mg/kg body weight)or sterile saline, and then treated with the Fluvastain and saline until they were killed .5 rats of every group were executed in 7,14,28,42 day. Immunohistochemistry and Westernblotting were used to measure the expression of TGF-β, ERK_(1/2) p-ERK protein.

本实验利用博莱酶素诱导大鼠肺间质纤维化,以氟伐他汀为代表研究他汀类药物对肺纤维化大鼠模型的干预作用,并通过观察氟伐他汀对ERK信号通路中重要调节酶ERK_(1/2)的表达及活化的影响,探索肺纤维化的信号传导机制,并为临床提供新的治疗思路。

Sulfur compounds in the diesel were selectively derived into methylsulfonium salts by reacting with iodomethane in the presence of silver tetrafluoroborate, and characterized by positive-ion electrospray ionization fourier transform ion cyclotron resonance.

在四氟硼酸银的催化作用下,以碘甲烷对直馏柴油进行甲基衍生化反应,使其中的有机硫化物转变成极性较强的锍盐,再用电喷雾-傅立叶变换离子回旋共振质谱仪进行检测。

Using the MTT assay, agarose gel electrophoresis, transmission electron microscope, TUNEL method and immunohistochemistry (PCNA, bcl-2),it was studied in this experiment that the inducing APO, anti-proliferation and affection of expression of bcl-2 gene before and afterAPO of the Rubia Cordifolia L with the 5-fluorouracil(5-fu) for MGC-803 cells of gastric carcinoma.

本实验通过MTT法、琼脂糖凝胶电泳法、透射电镜观察法、TUNEL法、免疫细胞化学法(PCNA、bcl-2),研究了茜草提取物联用5-氟尿嘧啶(5-fluorouracil,5-Fu)对胃癌MGC-803细胞株的诱导凋亡、抗增殖作用及凋亡前后bcl-2基因表达的影响。

Some useful fluorine-containing intermedi-ates were synthesized by the reaction of activated methylenecompounds or silyl enol ether with 2,2-dihydropolyfluoro-alkanoates or 2-hydropolyfluoroalk-2-enoates in the presenceof different bases.

进一步研究表明,在氢化钠的作用下,苯乙腈,苄基苯基甲酮也可以与2-氢多氟-2-烯酸乙酯发生亲核加成反应,苄基苯基甲酮的加成中间体经多聚磷酸环化,得到了间位氟烷基取代的α-萘酚衍生物。

Objective In this paper the teratogenic potential of fluoride and methylmercury were studied.

目的 研究氟化钠、甲基汞对骨组织的作用,以探讨其致畸性。

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Lugalbanda 是神和被崇拜了一千年多 Uruk古埃及喜克索王朝国王。

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