毛细胞

The research is focus on develop a new drug that is better curativeness and fewer side-effects.

大量的研究表明，老年性耳聋与耳蜗微循环障碍有密切关系，故临床上使用改善微循环的药物治疗老年性耳聋本实验研究使用豚鼠自然衰老模拟老年性耳聋，探讨老年性耳聋的发病机制，观察耳蜗毛细胞的形态学改变和听觉生理学变化。

Neurotrophic factors is a kind of chemistry which can increase the survival rate of neurone and the growth of nerval spines, it is important in neurone development, neurite growth, transmitter synthesis and cell languish.

神经营养因子又具有促进听觉神经系统发育并维持其正常功能的作用，其作用贯穿于从听板形成直至Corti器毛细胞与传入、传出神经末梢纤维之间建立突触关系的全过程。

The results are: 1 the stricture of the capillaries of stria vascularis was observed in most cochleae of rickety rats and, segmental deletions of the outer hair cells on the first turn of cochlea were found in a small number of rickety rats; 2 the perilymphatic ionized calcium concentration significantly re- duced and the threshold of CAP (Compound Action Poten- tials of the eighth nerve) significantly rose in rickety rats in comparison with those of normal control; 3 gentamicin results in an increase of the perilymphatic ionized calcium concentra- tion in rickety rats; 4 the cochleae of the rickety rats appeared to be less vulnerable to the ototoxicity of gentamicin than the normal one.

研究包括两个方面，其一是&佝偻病的感觉神经性耳聋及其对庆大霉素耳毒性作用的耐受性&，系用大白鼠建立维生素D缺乏性佝偻病动物模型，发现：（1）佝偻病大白鼠耳蜗血管纹毛细血管狭窄，少数动物耳蜗底回外毛细胞有节段性缺失；（2）佝偻病大白鼠的耳蜗鼓阶外淋巴钙离子浓度降低，CAP（听神经复合动作电位，以下简称CAP）听阈提高；（3）庆大霉素可使佝偻病大白鼠耳蜗外淋巴钙离子浓度上升；（4）佝偻病大白鼠耳蜗在功能和形态上都比正常者更能耐受庆大霉素的耳毒性损害。

Methods: Fifteen guinea pigs were randomly divided into 3 groups, in which the guinea pigs were peritoneally injected with normal saline, gentamicin, and both gentamicin and Egb (Egb+GM group). Distort production of otoacoustic emission thresholds were measured before and after injection. The apoptosis of hair cells were detected by TUNEL method.

健康豚鼠15只，随机分为3组，I 组为生理盐水组； II 组为庆大霉素组，造成损伤模型； III 组为银杏叶提取物和庆大霉素组，观测3 组豚鼠不同时期畸变产物耳声发射的改变， TUNEL法检测3组豚鼠毛细胞凋亡。

The result indicated that the etiology of presbycusis is cochlea microcirculation handicap, which will induce free radicals cumulation, hair cell loss and cilia changes.

这些结果表明，老年性耳聋的主要病理机制可能主要是由于微循环障碍导致大量自由基堆积，毛细胞缺失和纤毛结构改变。

Being the main reason of sensorineural hearing loss,the mechanism of aminoglycoside antibiotic\'s ototoxicity has been researched in many aspects,such as morphology, protein expression,gene regulation,and electrophysiological etc.But,most of those researches are focus on inner/outer hair cell,cochlear striae vascularis and spiral ganglion neuron.

在我国，氨基糖甙类药物导致的听力损失位居各种致聋因素之首，作为引起感音神经性聋的主要原因，学者们从形态、蛋白质表达、基因调控、电生理记录等各个方面对其耳毒性机理进行了大量研究，但研究主要集中在耳蜗的内、外毛细胞、血管纹、螺旋神经元部位。

Objective To investigate the change of the ribbon synapses in inner hair cells by using gentamicin.

目的探讨庆大霉素对耳蜗内毛细胞带状突触数量的影响及其意义。

Objective To investigate the interaction between tectorial membrane and inner hair cell stereocilia in the condition of vibration of the organ of Corti.

目的 探讨在Corti器振动过程中盖膜与内毛细胞静纤毛的相互作用关系；进一步阐明感音传导过程中，内耳Corti器微观结构可能的存在状态。

Methods Two-2D finite-element models were built based on the electron microscopic images of the organ of Corti from the guinea pig with two models of coupled and non-coupled between the tectorial membrane and stereocilia.

以豚鼠耳蜗底回Corti器的电镜图像为原型，建立盖膜与内毛细胞最长静纤毛接触和不接触的两种二维计算模型各一个，并作力学分析比较。

The injury of vestibular hair cells is one of the important factor in the vestibular deseases.

前庭毛细胞损伤是引起前庭系统疾病的重要原因之一。

As she looked at Warrington's manly face, and dark, melancholy eyes, she had settled in her mind that he must have been the victim of an unhappy attachment.

每逢看到沃林顿那刚毅的脸，那乌黑、忧郁的眼睛，她便会相信，他一定作过不幸的爱情的受害者。

Maybe they'll disappear into a pothole.

也许他们将在壶穴里消失