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The first adjustment was to replace logarithmfunction by S function for modeling the inner hair cells in cochlea,and the other was distributing frequency bins on frequency axis with the width of frequency bin proportionably increasing.Furthermore,the basilar membrane was modeled by Gammatone filterbank.

利用S函数取代对数函数对耳蜗内毛细胞进行模拟,将频率箱按照频率范围等比递增的方式在频率轴上进行分布;同时,利用Gammatone滤波器组进行耳蜗基底膜的建模。

The semicircular canals are the primary sensors of angular motion, and the utricle and saccule contain the otolith organs, which sense both the linear motion of the skull and the orientation of the skull with re- spect to gravity.

头的倾斜可以引起耳石所致的毛细胞弯曲,后者将神经冲动通过前庭神经传送到大脑。

Results①Make clear of the general principal during the morphologicaldevelopment of the C57BL/6 mouse inner ear and reconstructed the 3D modelof E13 inner ear;②The mature time of many histological structuresassociated closely with the hearing setout of C57BL/6 mouse were madeclear as basilar membrane in D10, scala vestibular and tympanicD4, Cortis tunnel D12, inner sulcus D10, tectorial membrane D10, haircells D12, spiral ganglion neurons D12 and neurofilament in cochlear axisD12-D14.③Outlined the time table and the patterns of the expressionsof those proteins associated with the inner ear development which includedproneural committed proteins, neuronal differential proteins,neurotrophic factors and neuron special proteins.

结果①HE常规染色大体观上了解了C57BL/6小鼠内耳形态发育E8-Da期间的一般规律并且获得了E13的三维立体图像;②获得了各种听功能密切相关的结构的成熟时间点,基底膜(D10)、鼓阶前庭阶(D4)、螺旋器隧道(D12)、内螺旋沟(D10)、盖膜(D10)、毛细胞(D12)、螺旋神经元(D12)和蜗轴纤维(D12-D14);③完成了前神经决定蛋白、神经分化蛋白、神经营养因子和神经元特异性蛋白等内耳发育相关的蛋白的表达时限表并详细观察了其在内耳各个部位表达随发育变化的特点:④Calbindin在E16以后的螺旋神经元没有表达,但是在scarpa神经元持续表达。

Results①Make clear of the general principal during the morphologicaldevelopment of the C57BL/6 mouse inner ear and reconstructed the 3D modelof E13 inner ear;②The mature time of many histological structuresassociated closely with the hearing setout of C57BL/6 mouse were madeclear as basilar membrane in D10, scala vestibular and tympanicD4, Corti\'s tunnel D12, inner sulcus D10, tectorial membrane D10, haircells D12, spiral ganglion neurons D12 and neurofilament in cochlear axisD12-D14.③Outlined the time table and the patterns of the expressionsof those proteins associated with the inner ear development which includedproneural committed proteins, neuronal differential proteins,neurotrophic factors and neuron special proteins.

结果①HE常规染色大体观上了解了C57BL/6小鼠内耳形态发育E8-Da期间的一般规律并且获得了E13的三维立体图像;②获得了各种听功能密切相关的结构的成熟时间点,基底膜(D10)、鼓阶前庭阶(D4)、螺旋器隧道(D12)、内螺旋沟(D10)、盖膜(D10)、毛细胞(D12)、螺旋神经元(D12)和蜗轴纤维(D12-D14);③完成了前神经决定蛋白、神经分化蛋白、神经营养因子和神经元特异性蛋白等内耳发育相关的蛋白的表达时限表并详细观察了其在内耳各个部位表达随发育变化的特点:④Calbindin在E16以后的螺旋神经元没有表达,但是在scarpa神经元持续表达。

Calpain expression significantly increased in aging rats than those in younger rats in hair cells, spiral ganglion and stria vascularis.

不同程度耳聋的耳蜗毛细胞、神经元和血管纹的钙蛋白酶表达趋势相似。

Delivery of a plasmid vector expressing math1 to neonatal organ of Corti cultures produced supernumerary hair cells in vitro.

在一些动物模型中如豚鼠、大鼠以及灰鼠等,能够诱导前庭毛细胞的再生。

AIM To explore the effects of infrasound on auditory thresh old and morphology of cochlear hair cells in guinea pigs.

目的 观察慢性次声暴露对豚鼠听阈及耳蜗毛细胞形态学的影响和作用特点。

The neomycin possess the powerful capability of eleminating vestibular hair cells of adult rat;Neomycin intracochlear administration via scale tympani can develop an ideal vestibular dysfunction animal model.Ⅱ.

新霉素对大鼠前庭毛细胞具有毁灭性的破坏作用,新霉素耳蜗内注射的方法可以建立理想的前庭功能障碍动物模型。

In the cochlear model, the model of the anteroventral cochlear nucleus is used to get the sychrony spectrum, the model of the posteroventral cochlear nucleus is used to get the firing rate spectrum and to detect the pitch.

对于中枢听觉系统:提出一个上橄榄复合体到耳蜗外毛细胞的自适应反馈控制模型,这个反馈由同步谱制导,实现了对刺激频率的选择注意,自适应于环境和语音的变化。

Basilar membranes were cultured and the number of hair cells and the expression of caspase-9 were determined by immunofluorescent staining.

对耳蜗基底膜进行离体培养,用荧光染色方法对毛细胞数量和caspase-9的表达进行观察。

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As she looked at Warrington's manly face, and dark, melancholy eyes, she had settled in her mind that he must have been the victim of an unhappy attachment.

每逢看到沃林顿那刚毅的脸,那乌黑、忧郁的眼睛,她便会相信,他一定作过不幸的爱情的受害者。

Maybe they'll disappear into a pothole.

也许他们将在壶穴里消失

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但是因为该公司年轻的企业文化——大多数员工在40来岁的时候都被请出公司——一时间没有好的人选。