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Here, we report a case of 38-year-old woman with generalized argyria. Pathologically, there were numerous minute fine brownish-black pigments fairly uniform in size, which were observed in the dermal interstitium, around the hair follicles, sebaceous glands, eccrine glands and the walls of capillaries. Darkfield microscopy showed refractile white particles.

本文报告一例发生在38岁女性的全身性银质沈著症,病理可见在真皮间质、毛囊、皮脂腺、汗腺和微血管壁周围有许多细小的棕黑色色素,暗视野显微镜下见到白色小点。

The clinical manifestations of acne, namely the comedo, papule, pustule, and cyst, would not form, regardless of increased sebaceous gland activity, as long as the sebaceous duct and infundibular portion of the hair follicle remained patent and lipid and cell debris were able to reach the skin surface.

痤疮的临床表现,即粉刺、丘疹、脓疱、囊肿,如果不是皮脂腺功能活跃,只要皮脂腺导管和毛囊漏斗部保持开放、细胞碎片能够排出到皮肤表面就不会形成。

A chronic fungous infection which involves the sebaceous glands and hair follicles may result in alopecia.

累及皮脂腺和毛囊的慢性真菌性感染都会引起脱发。

Results 8 days after intracutaneous injection,fully developed pigmented hair follicle formed.2 weeks later,skin surface of injection site became black and evlevated, a grey sac formed lined with keratinized epithelium,lots of hair follicles formed with black hair shafts and fully developed sebaceous glands.

结果皮内移植后8天可见有完整的黑色毛囊形成,2周见移植区皮肤呈黑色隆起,移植物形成一个灰白色囊,内衬角化上皮,周围见大量新生毛囊及黑色毛干,新生毛囊呈向心性排列,伴发育良好的皮脂腺。

We herein report a case of sebaceous trichofolliculoma in an 18-year-old boy.

我们报告一例发生在一位十八岁男性的皮脂腺发毛囊瘤。

The plasmid of pEGFP-N1 was preserved in our laboratory.②The rat vibrissa follicles were dissected under a stereomicroscope. The dermal sheath was moved by incubated in dispase. The bulge regions of the hair follicles in anagen phase were carefully cut between the arrector pili muscle and the sebaceous gland, and then incubated with a mixture of trypsin and EDTA. The cell suspension was selected, and cultured in 10% fetal bovine serum DMEM/F12 FAD medium. After 7 days culture, HFSC was obtained by rapid adhering on collagen Ⅳ.

实验方法:大鼠在体视显微镜下分离出含真皮鞘的完整毛囊,dispase消化,将毛囊从真皮鞘中挤出,收集形态完好且处于生长期的毛囊,分别在毛球部上端、皮脂腺下端横切毛囊,取中间部分置于胰酶和EDTA中联合消化,向所得细胞悬液中添加含10%胎牛血清DMEM/F12完全FAD培养基,常规培养7 d后,采用IV型胶原快速贴壁法两次筛选以分离纯化大鼠毛囊干细胞。

Mites such as demodex folliculorum and demodex brevis are natural hosts of the human pilo-sebaceous follicle.

螨类,如毛囊蠕形螨和蠕形螨的自然宿主是人类pilo -皮脂腺毛囊。

The sebaceous gland is formed embryologically as an outgrowth from the upper portion of the hair follicle.

从胚胎学上来说,皮脂腺是从毛囊上部向外生长形成的。

However, hair follicle stem cells prefer hair destiny in vivo, unless the injury of epidimal or sytogland occurs. In 1990, Cosarelis et al. proposed "The Bulge activated hypothesis", they think the signal moleculars emit from the dermal papillar induce the downward migration and differentiation of hair follicle stem cells.

然而,体内正常情况下毛囊干细胞首先向毛发谱系定向分化,只有在表皮或皮脂腺受到损伤时,它们才进行程序重组而向表皮或皮脂腺方向分化。1990年,Cosarelis等提出毛囊的&隆突激活假说&,认为来源于毛乳头的信号因子触发了毛囊干细胞向下迁移并分化,从而维持了毛发周期的正常循环。

Results C/EBPαand C/EBPβexpressed differently in the outer root sheath,follicular papilla,hair matrix and sebaceous gland in embryonic period.The positive signals were chiefly distributed in the nucleˉuses.The expression of C/EBPαand C/EBPβwere found in the basal cell layer of outer root sheath and sebaceous gland in the new born and maturation phase,The expression in nucleuses of outer root sheat cells decreased with the differentiation but enhanced oppositely in the cytoplasm.

结果 C/EBPα和C/EBPβ分别在胚胎期毛囊外根鞘,毛乳头,毛母质及皮脂腺细胞的胞核内强表达;新生儿毛囊峡部下端外根鞘基底层细胞的胞核内也存在强表达,基底内层胞核阳性信号逐渐减弱;而成体毛囊核内阳性信号仅定位于峡部下端外根鞘基底层及皮脂腺基底层。

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On the other hand, the more important thing is because the urban housing is a kind of heterogeneity products.

另一方面,更重要的是由于城市住房是一种异质性产品。

Climate histogram is the fall that collects place measure calm value, cent serves as cross axle for a few equal interval, the area that the frequency that the value appears according to place is accumulated and becomes will be determined inside each interval, discharge the graph that rise with post, also be called histogram.

气候直方图是将所收集的降水量测定值,分为几个相等的区间作为横轴,并将各区间内所测定值依所出现的次数累积而成的面积,用柱子排起来的图形,也叫做柱状图。

You rap, you know we are not so good at rapping, huh?

你唱吧,你也知道我们并不那么擅长说唱,对吧?