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Protect integrity of lysosome in hairy cells of the cochlea, and prevent from autolysis of the hair cells, which may be one of the action mechanisms.

保护耳蜗毛细胞内溶酶体的完整性,防止毛细胞的自溶性损伤可能是当归的作用机制之一。

Morphological and flourescent changes were assessed using confocal microscopy in whole-mount organ of Corti preparations. Results (1) After the animals were exposed to broadband noise at 122 dB SPL in 4 h/day for 2 days, both apoptosis and necrosis appeared in OHCs. The single strand DNA in apoptotic OHCs were observed both in guinea pigs and mice.(2) In normal OHCs, EndoG was distributed outside of nuclei. EndoG translocated from outside to inside of the nuclei in both apoptotic and necrotic OHCs following noise exposure.(3) The MNNG cochlear perfusion and noise exposure both caused the transloctation of AIF from the mitochondria to the nuclei. The translocation of AIF took place in both apoptotic and necrotic OHCs.

结果 (1)暴露于120 dB SPL的白噪声环境中每天4小时,连续2天后引起豚鼠和小鼠耳蜗外毛细胞凋亡时,其细胞核内产生ssDNA,而在正常细胞内没有三ssDNA;(2)在正常情况下,EndoG分布于耳蜗毛细胞的细胞核外,在暴露于上述噪声后发生凋亡和坏死的豚鼠耳蜗外毛细胞中,EndoG从细胞核外转移到细胞核内,细胞核中的EndoG显著增加;(3)豚鼠耳蜗外淋巴灌流烷化剂MNNG后发生耳蜗外毛细胞凋亡和坏死,在凋亡和坏死的耳蜗外毛细胞中,AIF自线粒体转移到细胞核,其变化与噪声损伤引起耳蜗外毛细胞凋亡和坏死时一致。

The nucleotide polymorphism existed in the SSU nrDNA gene sequences of species of Chaetoceros.

角毛藻的SSU nrDNA基因组内存在多态性,旋链角毛藻的基因组内多态性平均为0.45%。

It took more than 80 hours to make one-off the suit from Arctic wool, qiviuk, and rare South American wool, vicuna. The qiviuk and vicuna wools were blended with pashmina to create a cloth known as Vanquish II.

这件手工缝制的独一套西装取自北极圈内的麝香牛毛和南美洲的极品骆马毛,两种毛再与帕什米纳绒混在一起,便制造出这种叫做Vanquish II的毛料。

Now we don't know how aminoglycoside antibiotics damages hair cells, but there are some theories about it, such as:(1)AmAn affects the transformation among phosphoinositoln, inositol- 3-phophate and glycerine-2-acyl, also, it can cause the change of Ca2+ concentration in endocellular.

氨基糖甙类抗生素(aminoglycoside antibiotics, AmAn)损伤毛细胞的机制尚不清楚,但有以下几种学说:(1)影响了磷酸肌醇、三磷酸肌醇、二脂酰甘油间转化从而导致细胞内钙离子浓度的变化;(2)抑制G蛋白和鸟氨酸脱羧酶活性;(3)氨基糖甙类抗生素能引起内耳毛细胞的凋亡。

Results The intramural capillary lymphatics of rat's rectum were observed in deep lamina propria of tunica membrane and the dermal papilla layer of anal pectin. The intramural capillary lymphatics and lymphatics were both observed in tela submucosa, reticular layer, hypodermis and intermuscular and serosa. The capillary lymphatics in rectums' wall have the similar ultrastructure feature to normal ones. Three kinds of endothelial cells junctions are overlapping junctions, embedding-junctions and end to-end-type junctions. About 21% of cell-junctions are opening types. There are normal organelles and many vesicals in the endothelial of capillary lymphatics.

结果 直肠壁内的毛细淋巴管见於黏膜固有层深部和肛梳区真皮乳头层;在黏膜下层和肛梳区的网状层、皮下组织以及肌层和浆膜层内均有毛细淋巴管和淋巴管,直肠壁内毛细淋巴管的超微结构具有一般毛细淋巴管超微结构的特点,内皮细胞连接有重叠、嵌插和端端连接3种类型,处於开放状态约占21%;胞质内含有一般的细胞器,幷含有大量的囊泡。

The actual hair shaft, as well as an inner and outer root sheath, develops from the mitotically active undifferentiated cells of the matrix portion of the hair bulb.

实际的毛干和内、外根鞘,是毛球的母质部分的未分化细胞活跃分裂的结果。

A non-lacerational technique to collect cells in an oral cavity utilizes a brush with bristles (40) which have an abrading surface that collect cells from the superficial, intermediate, and basal layers of the oral tissue.

一种用于采集口腔内细胞的不划破技术采用具有刷毛(40)的刷子,该刷毛具有用于从口腔组织的浅层、中间层和基层中采集细胞的研磨表面。

The cochleae of animals were dissected. propidium iodide, a dna intercalating fluorescent probe, was used to trace the morphological changes in ohc nuclei. f-actin staining was used to determine missing ohcs. the single strand dna in apoptotic ohcs of guinea pigs and mice, and apoptosis inducing factor and endonuclease g in ohcs of guinea pigs were examined by immunofluorescence method.

分离解剖耳蜗后,用碘化丙啶染色细胞核、pholloidin染色f-actin,免疫荧光抗体分别染色单链dna、核酸内切酶g和凋亡诱导因子(apoptosis inducing factors, aif),制备耳蜗铺片,激光共聚焦显微镜下观察凋亡和坏死毛细胞内的荧光信号变化。

S1398 proteinase. It is found that their varying rules are resemble, concentrations of them rise sharply at the first time when components between hair root sheath and hair pocket, hair-bulb and hair papilla are destroyed as a result of enzymes leading to remove hairs.

结果表明,它们三者的变化规律具有相似性,其浓度都在脱毛的最初阶段内出现急剧性的增长,此段时间也正好是酶作用毛根鞘与毛袋之间及毛球与毛乳头之间的组分,从而使毛脱落的时间。

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This one mode pays close attention to network credence foundation of the businessman very much.

这一模式非常关注商人的网络信用基础。

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