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Objective To isolate new conotoxins of Conus textile from the South China Sea,provide new conopeptides for drug discovery and design, and investigate the effects of living environment on toxin secretion by comparing the compositions of the conotoxins of this species from different areas.

目的从中国南海织锦芋螺中分离新的芋螺毒素,为药物发现、药物设计提供新的活性多肽或前体多肽,比较不同地域织锦芋螺毒素的构成,研究环境对织锦芋螺毒素分泌的影响。

Agkistrodotoxin, a presynaptic neurotoxin and one of the two neurotoxins from the snake venom of Agkistrodon halys Pallas, has been further purified by DEAF -cellulose and CM-Sephadex column chromatography and vertical slab polyacrylamide gel electrophoresis.

本文在前文的基础上,改进了蝮蛇神经毒素的分离方法,纯化了蝮蛇毒中的两个神经毒素之一,突触前神经毒素Agkistrodotoxin,并对其生化特性进行了分析。

Botox is the marketing name given to a neurotoxin called botulinum toxin A.

肉毒杆菌是一种叫肉毒菌毒素的神经毒素。

The objective of this study is to picture the signal tranduction pathway of apoptosis induced by MC so as to further investigate the impact of MC on transcription, expression and regulation of apoptosis gene and the related biological effects; illustrate the toxicological mechanism of MC; as well as discover the new biomarkers invovled.

本研究工作的目的是通过功能基因组分析的技术平台,探讨微囊藻毒素诱导肝组织细胞凋亡的信号转导通路,以便在此基础上,进一步深入研究该毒素对凋亡功能基因在转录、表达、调控水平上的影响,及由此引发的生物学效应;揭示微囊藻毒素的凋亡毒理机制,同时发现新的生物标记物。

The clavacin toxin generally exists in the concentrated apple-juice for export, especially in the middle and later period of the squeezing season, the risk the content of the clavacin toxin exceeds the standard is very big in the case that the decay ratio of the raw material of the apple is higher. In the practical examination and verification of HACCP food safety management system, people found various methods and paths for controlling the clavacin toxin in the production of the concentrated apple-juice, b...

棒曲霉毒素在出口浓缩苹果汁中普遍存在,特别是在榨季的中后期原料苹果的腐烂率较高时其质量分数超标的风险很大,在HACCP食品安全管理体系审核实践中,发现浓缩苹果汁生产过程中,控制棒曲霉毒素的方法和途径有多种,但不论哪一种或多种组合应用都应关注原料果的品种、生产季节和储存温度,因为这些因素是降低棒曲霉毒素质量分数和生产成本的关键因素。

In my search for a nail polish with less toxins I came across Loreal Jet Set and Loreal Steel Color which do not contain formaldehyde, toluene or dibutyl phthalate.

我对含少量毒素的指甲油做了一项调查,在调查中我偶然发现了欧莱雅速丽指甲油和欧莱雅时尚珍藏指甲油,它们不含甲醛,毒素或邻苯二甲酸二丁酯。

This project studied the mechanism of a newfound phytotoxin from Alternaria alternata Keissler that infects Crofton weed. According with the result from experiment, the project group drew a conclusion that the toxin did not inhibit respiration in mitochondrion, so the key problem was whether the toxin inhibited photosynthesis in chloroplast.

本项目重点研究新近分离纯化的紫茎泽兰致病型链格孢菌毒素的致病机理,项目组依据实验结果排除了毒素抑制线粒体呼吸作用的可能性,把重点放在毒素对叶绿体光合作用的影响上。

A heterotrophic organism that ingests other organisms or organic matter in a food chain .

随着毒素流经食物链,毒素的含量可能增加地可能降低。

Buckwheat, rapeseed, cottonseed cake and tapioca included some toxins, therfore feed by crush, immersion and silage fermentation without toxins.

含有某些毒素的荞麦、菜籽饼、棉籽饼、鲜木薯等,一般须经粉碎、浸水、发酵或青贮,待毒素去掉后方可生喂。

Antinociception and VGSC-modulation of BmK IT2 and BmK AS—1. The results from nociceptive flexion reflex and plantar radiation heat showed: BmK IT2 (a depressant insect-selective neurotoixn) and BmK AS-1 (a new-type β-1ike neurotoxin) have significant antinociceptive effects on rat peripheral nerve system. The antinociceptive effects of BmK IT2 on the carrageenan-inflamed rats were significantly stronger than those on the normal rats. Whole-cell patch-clamping showed: Both TTX-S and TTX-R Na〓 currents induced from rat DRG neurons were significantly inhibited by BmK IT2 and BmK AS—1, and BmK IT2 was more sensitive to TTX-R than TTX-S component. All the results suggested: the peripheral antinociception of BmK IT2 and BmK AS—1 might be attributed to the inhibitory effects of them on the TTX-S and TTX-R Na〓 channel located on the peripheral ends of rat DRG neurons with small diameter.

中文题名特异性钠通道调制剂-长链蝎神经毒素的药理功能研究副题名外文题名 The study of pharmacological function of the specific modulators on voltage-gate Na+ channel-long chain scorpion neurotoxin 论文作者谭智勇导师吉永华研究员学科专业生理学研究领域\研究方向学位级别博士学位授予单位中国科学院上海生命科学研究院学位授予日期2002 论文页码总数93页关键词神经毒素毒理学电压门控钠通道东亚钳蝎钠通道调制剂馆藏号BSLW /2003 /R338 /22 本论文工作利用细胞和行为药理技术系统地研究了东亚钳蝎长链神经毒素的抗伤害性效应、对电压门控钠通道的电生理调制作用、改变胞内离子浓度的效应,并分析了相关的药理功能机制。

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On the other hand, the more important thing is because the urban housing is a kind of heterogeneity products.

另一方面,更重要的是由于城市住房是一种异质性产品。

Climate histogram is the fall that collects place measure calm value, cent serves as cross axle for a few equal interval, the area that the frequency that the value appears according to place is accumulated and becomes will be determined inside each interval, discharge the graph that rise with post, also be called histogram.

气候直方图是将所收集的降水量测定值,分为几个相等的区间作为横轴,并将各区间内所测定值依所出现的次数累积而成的面积,用柱子排起来的图形,也叫做柱状图。

You rap, you know we are not so good at rapping, huh?

你唱吧,你也知道我们并不那么擅长说唱,对吧?