毒性

This study will assess elementarily the security and effectiveness of The root and leaf of Panicled Fameflower through the experimental studies on their pharmacodynamics and acute toxicology, provid possibly theorems and experimental foundations for Panicled Fameflower' s edibleness, planting and study.

本课题通过土人参根、叶的药效和急性毒性实验研究，对土人参根、叶治疗"脾虚"证、土人参叶"解毒消痈"的疗效和部分作用机制做出初步评价、并取得土人参根、叶急性毒性数据，为保健中药蔬菜土人参的食用提供客观的药效学和急性毒性的实验依据，以促其进一步推广应用、种植、研究。

In this paper,toxicity test using poison fish is spplied to momitoring the effluent from 121industrial dischargc points in conjumction with taking K2Cr2O2 as rcfcrcncc,aimed at quantifying the results of acure toxicity test.

运用鱼类急性毒性力法对抚顺市重点工业污染源21个污染排放口水样的毒性进行检测，以K2Cr2O7 作参比毒物，使此法所测得的急性毒性值定量化。

The toxic compound was traced by lettuce germination test guided fractionation and HPLC purification, and was identified as 3β-formyl usolic acid on the basis of 1H and 13C NMR experiments. It is the first time to find this compound from the order of Myrtaceae

用高效液相色谱对桉树凋落叶中毒性物质进行分离、纯化，以小麦、绿豆、大速生菜为指示植物，对分离到的物质进行毒性跟踪，分离到一个毒性较强的组分，经1H氢谱和NMR鉴定为3–β甲酰基–乌索酸。

Results ATP andEAA Neurotransmitter Gly were greatly increased in the bilirubin induced neurotoxicity brain; neuralcytosolic Ca2 + in the bilirubin precipitated brain tissue was significantly more than that in the controlgroup; NMDA receptor antagonist GAPA could significantly decrease the cytosolic Ca2+ overload.

结果 胆红素毒性脑组织ATP含量显著降低，细胞外Gly与细胞内Ca2+显著升高；GAPA不影响胆红素毒性脑组织ATP含量，但可显著降低细胞内Ca2+，减轻胆红素毒性脑水肿。

In these studies, gelsemium were obtained from suburb YuLin city, Guangxi province .The gelsemium total alkaloids which were the main toxicity constituents of the plant were extracted, isolated , identified .Acute toxic and subchronic tests on mice were further studied. The experiment established foundation of production and application of poisonous plant Gou-Wen.

本试验以广西玉林市郊外的钩吻植株为材料，提取、分离、鉴定其主要毒性成分钩吻生物碱，并进一步研究了钩吻生物碱对小鼠的急性毒性和亚慢性毒性作用，为有毒植物钩吻的生产应用提供了理论依据。

Daunorubicin is a potent anti-leukemia agent. However, it also has cardiac, genic and genital toxicities.

柔红霉素是强效的抗白血病制剂，但具有心脏毒性，基因毒性和生殖器官毒性。

Treated with high concentration of piperine （0.56 mmol/L） for 24 hours and 48 hours respectively, following a period of growth retardation, the cells of 24-hour-group could recover slowly while the 48-hour-group showed inconvertibility.

由此认为：胡椒碱对C6/36细胞株有毒性作用，但药物诱导的细胞凋亡在细胞毒性作用机制中不占主导地位；胡椒碱对C6/36细胞的作用有时间依赖性，延长作用时间，药物对细胞的毒性作用增强。

The biocompatibility of poly(3-hydroxybutyrate-co-hydroxyocatanoate), a new biodegradable co-polymer scaffold, was evaluated with a series of tests, including cytotoxicity test, acute systemic toxicity test, hemolysis test, pyrogen test, genetic toxicity test, intracutaneous stimulation test and subcutaneous implantation test.

文章选用细胞毒性实验、急性全身毒性实验、溶血实验、热源实验、皮内刺激实验、遗传毒性实验和皮下植入实验等7个生物相容性实验对生物可降解支架材料羟基丁酸与羟基辛酸共聚体的生物相容性进行评价。

The initial SAR studies indicated:(1) the presence of a linker of methene at the N-1 may be beneficial to anti-HIV activity, while longer chain could enhance toxicity;(2) substituted phenyl at the C-2 could reduce toxicity;(3) 6-substituted benzimidazoles generally showed higher anti-HIV activity than 5-substuted ones;(4) the presence of a halogenated benzyl ring at the N-l would enhance anti-HIV potency and decrease cytotoxicity.

初步构效分析提示：(1)苯并咪唑环1位侧链间隔基为亚甲基时活性最好，侧链延长，毒性增大；(2)苯并咪唑2位侧链无间隔基毒性相对较低；(3)苯并咪唑6位取代活性高于5位取代；(4)苯并咪唑1位芳环用卤素取代，毒性明显降低。

The initial SAR studies indica ted:(1)the presence of alinker of methene at the N-1may be beneficial to anti-HIV activity,while longer chain could enhance toxicity;(2)substituted phenyl at the C-2could reduce toxicity;(3)6-substituted benzimidazoles generally showed higher anti-HIV activity than 5-substuted ones;(4)the presence of ahalogenated benzyl ring at the N-l would enhance anti-HIV potency and decrease cytotoxicity.

初步构效分析提示：(1)苯并咪唑环1位侧链间隔基为亚甲基时活性最好，侧链延长，毒性增大；(2)苯并咪唑2位侧链无间隔基毒性相对较低；(3)苯并咪唑6位取代活性高于5位取代；(4)苯并咪唑1位芳环用卤素取代，毒性明显降低。

I am accused of being overreligious," she said in her quiet, frank manner,"but that does not prevent me thinking the children very cruel who obstinately commit such suicide.""

客人们在卡罗利娜·埃凯家里，举止就文雅一些，因为卡罗利娜的母亲治家很严厉。

Designed by French fashion house Herm è s, this elegant uniform was manufactured in our home, Hong Kong, and was the first without a hat.

由著名品牌 Herm è s 设计，这件高贵的制服是香港本土制造，是我们第一套不配帽子的制服。