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The azocyclotin is high to the ichthyotoxin, is extremely low to the honeybee toxicity, the birds take orally LD50 are 175-375mg/kg.

三唑锡对鱼毒性高,对蜜蜂毒性极低,鸟类口服LD50为175-375mg/kg。

MethodsThe antipyretic activity of SMPS was observed in rats with high temperature induced by dried yeast and 2,4-dinitrophenol; biliary duct cannula bile at 0.5,1,1.5,2,2.5 h after intraduodenal administration in rats was collected and counted to observe the effect of SMPS on biliary secretion;the weight of cholecyst in mice was counted to observe the effect of SMPS on the cholecyst of mice;the acute toxicity test of SMPS was done with mice.

目的研究玉米须多糖的清热利胆作用及急性毒性。方法采用干酵母、2,4二硝基苯酚致大鼠发热的模型观察玉米须多糖的解热作用;采用胆管引流法分别收集并计量给药后0.5,1,1.5,2 ,2.5 h的胆汁的方法观察SMPS对肝脏分泌胆汁的影响;采用测定小鼠胆囊重量的方法观察SMPS对胆囊的影响;对SMPS进行了小鼠急性毒性实验。

Results show that, following the leaching time extending, the leaching concentrations of heavy metals and lixiviate toxicity of heavy metals increase in the fly ash. When the ratio of liquid and solid add, the leaching concentrations of heavy metals obviously become big, and the Cd's leaching concentration is the biggest, when the ratio of liquid and solid is 90, the Cd's leaching ratio exceed the percent of 70. At the time pH is about 7, the leaching concentrations of heavy metals are the lowest. When the grain size is the bigger or little, the leaching concentrations of heavy metals are lower, however when the grain size is 250-900 μm, the concentrations are higher. After fly ash melt in the high temperature, the lixiviate toxicity of heavy metals greatly reduce, which explains that the effect of melting on heavy metals' stabilization is very good.

结果表明,随着浸出时间的增加,飞灰绝大部分重金属的浸出浓度增高,浸出毒性增强;液固比增加,大部分重金属的浸出率大大提高,其中重金属Cd的浸出率最大,在液固比为90时,飞灰中的Cd的浸出率达到70%以上;pH为中性左右的时候,医疗垃圾飞灰中的大部分重金属的浸出液浓度最低;颗粒尺寸在较大或者较小时,医疗垃圾飞灰中的大部分重金属浸出浓度较小,大部分重金属在颗粒尺寸250~900 μm时,重金属的浸出浓度较高;飞灰高温熔融后,重金属的浸出毒性大大降低,说明熔融对重金属有很好的固化效果。

In the acute toxicity experiments, the 96h-LC50 were 1.0×105 cells·mL-1 for the intact algal solution and 8.0×104 cells·mL-1 for the lysate. In a 7 day subacute experiment on the larvae, higher concentrations of algal solution inhibited S. macrocephalus larvae. The toxicity of the algal solution was higher than that of the lysate at the same concentration.

在仔鱼96h的急性毒性实验中,微小亚历山大藻对仔鱼的96h理论半致死浓度分别为1.0×105 cell·mL-1、8.0×104 cell·mL-1,而在7d的亚急性实验中,高浓度藻细胞液对仔鱼的生长发育有一定的抑制作用,且相同浓度下,藻细胞液产生的毒性较藻细胞破碎液大。

The bio-toxicity of the dinoflagellate Alexandrium minutum on black seabream was studied by observing the acute toxicity and subacute toxicity of A. minutum on the S. macrocephalus embryo and larvae. The presence of A.

通过微小亚历山大藻对黑鲷胚胎及仔鱼的急性和亚急性毒性的实验,研究了微小亚历山大藻其藻细胞液和细胞破碎液对黑鲷幼体的生物毒性效应。

In the acute toxicity experiments, the algal solution and breakup solution of the concentration of 96h-LC50 were 1.0×105cells/mL and 8.0×104cells/mL, respectively. In the subacute 7 days experiment of the larvae, higher of the algal solution has the inhibition effect on sparus macrocephalus larvae. The toxicity of algal solution was higher than that of breakup solution at the same concentration.

在仔鱼96h的急性毒性实验中,微小亚历山大藻对仔鱼的96h理论半致死密度分别为1.0105 cell·mL-1、8.0104 cell·mL-1,而在7d的亚急性实验中,高浓度藻细胞液对仔鱼的生长发育有一定的抑制作用,且相同浓度下,藻细胞液产生的毒性较藻细胞破碎液大。

The bio-toxicity effect of Alexandrium minitum cell solution and breakup solution on sparus macrocephalus was studied by the acute toxicity and subacute toxicity of Alexandrium minitum on the sparus macrocephalus embryo and larvae.

通过微小亚历山大藻对黑鲷胚胎及仔鱼的急性和亚急性毒性的实验,研究了微小亚历山大藻其藻细胞液和细胞破碎液对黑鲷幼体的生物毒性效应。

It is urgent and important for further understanding of these toxicities to develop adequate staging systems and mechanistically driven therapies, in which the quality of life and consistent antineoplastic therapy can be ensured.

了解这些皮肤毒性的机制,制定适当的毒性分期标准,进而给予正确的防治,对确保患者生活质量及抗肿瘤治疗的连续性都十分重要。

Various classes of organic chemicals and diverse molecular structures often indicate complexity and multiplicity of toxic modes of action. Thus developing QSARs that are both mechanistically significant and highly predictive for diverse classes of chemicals that involved multiple or mixed mechanisms of toxic action will be advantageous and preferable.

有机污染物的种类多种多样,毒性机制也复杂多样,因此发展既能够准确预测包括多种作用机制的化合物的毒性,又具有明确物理意义的理想QSAR模型是结构活性关系技术发展的必然方向。

Micronucleus test results exhibited that significant differences in micronuclear rates were determined between 0.4 mL bone cement and 0.4 mL microsphere-coated bone cement groups and negative control group, but no significant difference was detected among other groups. This revealed that this microsphere-coated bone cement leaching liquor did not show significant cell heredity toxic effects. Nevertheless, microsphere-coated bone cement in the high concentration and high dosage groups exhibited low toxic effects, mainly showing increased hemolysis rate and micronuclear rate. Thus, it was necessary to control the dosage and concentration of microsphere-coated bone cement.

微核实验结果显示除0.4 mL骨水泥组和0.4 mL微球骨水泥组的微核率与阴性对照组差异有显著性意义,其余各组差异无显著性意义,说明该微球骨水泥的浸提液无明显细胞遗传毒性作用,但是高浓度和高剂量组的微球骨水泥仍有较低的毒性作用,主要表现为溶血率和微核率的提高,因此在应用时要适当控制微球骨水泥的剂量和浓度。

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