死亡表

Interstitial pneumonia,carnification and haemorrhage existed in the lungs of all the died piglets.

死亡猪表现为严重的出血性、间质性肺炎，肢体远端皮表出血。

The expression level of metabolitic enzyme (CYP1A1, CYP1B1) and its correlation with cell differentiation /apoptosis were studied as well. The influence of resveratrol in cell cycle was determined with FCM. Results 1 Resveratrol not only suppresses the growth of medulloblastoma cells in a dose and time related fashion but also induces cell differentiation and apoptosis. Resveratrol promotes differention of UW228-1,-2 cells to forward glia, UW228-3 and Med-3 cells to neuron. A treatment of resveratrol in the concentration of 100μM for 48hrs comit most of cells die of apoptosis. 2 Among the four cell lines Fas and Caspase-3 were constantly expessed, whereas FasL was absent irrespective to the drug treatment. 3 ICC, RT-PCR, Western-blot hybridization and EROD enzymatic activity assay demonstrated that expression of CYP1A1 is different after treatment with resveratrol in four cell lines, up-regulated in three UW228 cell lines in a dose dependent manner but down-regulated in Med-3 cells. Suppressive effect of resveratrol on CYP1B1 expression is the same among four medulloblatoma cell lines. 4 Cell cycle distribution of UW228-3 was greatly changed after treatment.

结果：1、白藜芦醇以时间和剂量依赖性方式抑制髓母细胞瘤细胞生长，同时促进细胞的分化和凋亡：白藜芦醇促使UW228-1、-2靶细胞向神经胶质细胞方向成熟分化，UW228-3、Med-3细胞向神经元细胞方向成熟分化，以100μM作用48小时效果显著；2、四个细胞系均有Fas和Caspase-3表达，但无Fas-L基因表达和蛋白活性产生，因此难以形成Fas相关性死亡通路；3、白藜芦醇处理前后CYP1A1基因的表达在各细胞系略有不同：UW228-1，-2，-3三个细胞系白藜芦醇以剂量相关性方式上调CYP1A1的表达，而Med-3细胞系，白藜芦醇却抑制CYP1A1的表达；四个细胞系在白藜芦醇处理后CYP1B1的表达均受到抑制；4、UW228-3细胞系经白藜芦醇作用后细胞周期有较大改变，表现在G0/G1期在整个细胞周期中所占的比例增加，而其它时期则相应减少。

The C-terminal half is responsible for its binding ability as to homeodomains, HIRA-interacting protein 3(HIRIP3), and core histones. HIRA is well conserved during the long evolutionary pathway which indicates that this protein may be essential for life development.

HIRA在从酵母到人类的长期进化过程中高度保守，说明其在生命发育过程中起着重要作用。mHira基因敲除的小鼠胚胎表现出复杂的表型缺陷，原条扭曲，脊索和神经管发育异常，发育至孕中期时全部死亡。

Mouse models of this genetic defect have been unsatisfactory because homozygote null animals die early in development and heterozygotes do not exhibit a cardiac phenotype.

这种遗传缺陷的小鼠模型并不能令人满意，因为纯合子缺陷动物在发育早期就会死亡，而杂合子又不能显示心脏表型。

The mortality rate is the probability of the risk of human's death, and the mortality table is the statistical table which shows the mortality rate of each age.

死亡率是人类面临死亡风险的概率，而生命表则是死亡率按年龄归纳成的统计表。

Cytotoxic effect was demonstrated with nitrogen mustard, nitromin, sarcolysin, thio-TEPA and myleran at concentrations of 7, 10, 25, 35, 100, and 100μg/ml respectively.

氮芥及氧化氮芥在7—10微克/毫升，溶肉瘤素和新恩必恨于25—35微克/毫升，三乙酰硫代磷酰胺和丁二醇二甲磺酸酯在100微克/毫升，都出現了显著的細胞毒作用，使細胞很快死亡溶解；但6-巯基嘌吟和氨基喋吟未表現作用。

When already described standard neurodifferentiation protocols were used, cultures exhibited only transient neurodifferentiation followed by either redifferentiation into a fibroblast-like phenotype or massive cell death.

采用神经分化的标准方法，再分化为纤维样表型细胞或大量死亡之后有部分由部分向神经系统方向分化。

Gabriel Lopez-Berestein, M.D., professor of experimental therapeutics and study co-author, notes that the research also shows that the self-consuming cell death preented by TG2 is independent of a prominent molecular pathway also known to regulate autophagy called the mammalian target of rapamycin.

实验疗法部的教授，文章的共同作者，医学博士Gabriel Lopez-Berestein指出，这项研究同样表明了TG2保护自我消化细胞免于死亡是一条独立的重要分子旁路，也是雷怕霉素调节自噬作用的哺乳细胞靶点。

Take the blood specimen to measure the hepatic and renal function and the tissue biopsy after the active and motive abnormities called toxical manifestation such as posture changes, abnormal sound, uneasiness, quiet, thrill, ataxia, convulsion and so on with toxic dose. Measure the tissue biopsy after death with lethiferous dose. If no toxicity or death occur after the experiment of 12 weeks, measure the hepatic and renal function and the tissue biopsy. There was no rat which had the toxical manifestation such as active or motive abnormities and 3 rats died because of environment or others after the experiment of 12 weeks.

实验中分别测定治疗剂量组小鼠在用药4周，8周，12周后的肝肾功能，并进行组织病理检查；中毒剂量组小鼠在出现行为、动作异常，如改变姿势、叫声异常、不安、安静、震颤、运动失调、惊厥等中毒表现时，取血液标本测定肝肾功能，并进行组织病理检查；致死剂量组小鼠发生死亡后进行组织病理检查；若12周实验结束时无小鼠出现中毒表现或死亡，则取血液标本测定肝肾功能，并进行组织病理检查。12周实验结束时，无小鼠出现动作、行为异常等中毒表现，有3只小鼠因为环境或其它原因发生死亡，病理检查结果正常。

Thirty advanced cancer patients who resident in the hospital in certain areas of Taipei and their families (N=60) were recruited. Using the revised TRIG questionnaire collected data. Family caregivers were interviewed for the qualification of the case respectively when the patients were still in the hospital and one month after the patients died. The questionnaire was analyzed via software SPSS.

本研究之目的在探讨癌症末期病人死亡地点不同与家属哀伤反应的相关性及探讨癌症末期病人死亡地点如愿与否与家属哀伤反应的相关性，采前瞻性研究法，以台北巿某区域医院之30对住院癌症末期病人及家属(N=60)为收案对象，以修改后的TRIG量表为工具，针对符合收案条件者分别於住院时及丧亲一个月后进行访谈，并完成问巻，结果以SPSS套装软体进行资料之统计分析。

Breath, muscle contraction of the buttocks; arch body, as far as possible to hold his head, right leg straight towards the ceiling (peg-leg knee in order to avoid muscle tension).

呼气，收缩臀部肌肉；拱起身体，尽量抬起头来，右腿伸直朝向天花板（膝微屈，以避免肌肉紧张）。

The cost of moving grain food products was unchanged from May, but year over year are up 8%.

粮食产品的运输费用与5月份相比没有变化，但却比去年同期高8％。