步甲

METHODS:This compound was synthesize by steps of ammonolysis,hydrogenize,diazotization and coupling from 4-nitrobenzoyl chloride.

以对-硝基苯甲酰氯为原料，经氨解、氢化、重氮化及偶合四步反应得到了巴柳氮。

In this dissertation, we choosed anisole as starting material, via chloromethyla tion, cyanogenation, to prepare methoxybenzeneacetonitrile, then fractionated in a fractionating tower, and finally...

本论文也对两步的反应条件进行了探索，获得了比较理想的反应条件。文中还对对甲氧基苄氯自聚的原因与机理进行了探讨，并找到了比较理想的阻聚剂，使得粗品收率提高了10％。

A mechanism involved in the second [5 + 1] annulation step, includinga formal [5 + 1] annulation and accompanied chlorovinylation, chloroformylation,amination and aromatization reactions, is proposed.

并对第二步反应机理进行了推测，其中包括了一个一般的[5 + 1]加成反应及伴随此加成反应而发生的氯化乙烯化，氯化甲酰化，氨化和芳构化反应。

In the first step of thedouble annulation route, 2-amino-3-carbamoyl-5,6-dihydro-4-pyridones 2 werecreated in high to excellent yields by a formal [5C + 1N] annulation reaction ofketene--acetals 1 with ammonia.

第一步，二硫缩烯酮1和氨源通过[5C + 1N]加成反应产率极高的得到了2-氨基-3-氨基甲酰基-5，6-二氢-4-吡啶酮2。

In this thesis, a convenient and efficient synthesis of highly functionalizeddihydropyrido[2,3-d]pyrimidines via a double [5 + 1] annulation strategy startingfrom easily available α-alkenoyl-α-carbamoyl ketene--acetals 1 and cheapreagents (NH4OAc, DMF, and POCl3) has been developed.

本论文探索了一种简便有效的合成高度官能化的二氢吡啶并[2，3-d]嘧啶的方法，此方法由易得的α-乙酰基-α-氨基乙酰基二硫缩烯酮1和便宜的试剂(醋酸铵，二甲基甲酰胺和三氯氧磷)通过两步[5 + 1]加成而实现。

With the occurrence of H2/Pd-C and ethyl formic ester,the reduction of the nitro group and the formylation of the amino group could be finished in one step.

但是在甲酸乙酯存在下，用H2/Pd-C对Ⅶ的硝基进行还原，得到的Ⅷ中的氨基可当即被甲酰化，使由Ⅶ到Ⅳ的两步反应一步完成。

Dioxymethylene Mandelic Acid was synthesized by Benzo[1,3]- dioxole which was prepared from catechol .

以邻苯二酚为原料制备胡椒环，然后再从胡椒环合成3，4—亚甲二氧基苯乙醇酸，研究了第二步的反应温度、反应时间以及物料摩尔比对收率的影响，该步反应收率为88%。

Results The synthesis condition was improved. The method of methane sulfonic acid/DL-methionine was found an ideal substitute of BBr3 for less cost. While using hydrobromic acid, the O-demethylation and hydrolyzation could be combined in one stage.

结果 优化了纳洛酮的合成工艺，甲磺酸／DL-甲硫氨酸法试剂价格低廉，可降低生产成本；而氢溴酸法不但试剂价格更低，还可将去氧甲基化和水解合并为一步反应，使新工艺的总收率提高到59.90%，产品质量符合中国药典。

Bromo-5-formyl -3-methylpyrrole is an important intermediate of tolyporohin. On the base of introducing the present research and development of tolypo- rohin and pyrroles ramification at home and abroad, an emphasis was made on synthesis of 2-Bromo-5-formyl -3-methylpyrrole and the technical conditions of all steps, which was described as follows. Diethyl 3,5-dimethylpyrrole-2,4-dicarboxylate was made by nitrification, reduction and cycle of ethyl acetoacetate.

由于2-溴-5-甲酰基-3-甲基吡咯是合成托尼卟吩的重要中间体，本文在阐述了当前托尼卟吩及吡咯衍生物的国内外研究和开发的基础上，重点研究了2-溴-5-甲酰基-3-甲基吡咯的合成，并对各步反应进行了工艺研究，具体合成步骤如下：本文通过对乙酰乙酸乙酯的亚硝化、还原、成环，反应生成吡咯单环衍生物2，4-二乙氧羰基-3，5-二甲基吡咯。

Force, the infantry of both sides are heavily armored infantry spear, and bow and arrow using the composition of the light infantry, Joseph to enter into further divided into teams of infantry and even plain mountain infantry and infantry, the former to use the light of the Large Shield and the Tomahawk, which the use of spears.

双方的步兵步队都由披甲持矛的重装步兵以及使用弓箭的轻步兵组成，赫缔步队的步兵甚至分为山地步兵和平原步兵，前者使用轻便的圆盾和战斧，后者使用长矛。

I didn't watch TV last night, because it .

昨晚我没有看电视，因为电视机坏了。

Since this year, in a lot of villages of Beijing, TV of elevator liquid crystal was removed.

今年以来，在北京的很多小区里，电梯液晶电视被撤了下来。