次因子

IL 1β and IL 6 levels in supernatant of homogenates of cerebral cortices were measured by the Enzyme Linked Immunosorbent Assay.

28只C57BL/6J雄性小鼠接受MPTP 25 mg/kg ip注射连续5 d，对照组（10只）注射生理盐水，在最后一次注射的第1（10只），第3（8只）和第14日（10只）杀鼠，然后用酶联免疫吸附的方法检测大脑皮质匀浆液上清内细胞因子IL 1β和 IL 6的水平。

Specific gene expression of the pro-inflammatory cytokine IL-1β and the type II IL-1βreceptor (IL-1RII, 'decoy receptor') was studied in skin of rainbow trout Oncorhynchus mykiss (Walbaum, 1792) fry during infection with the ectoparasitic monogenean Gyrodactylus derjaini Mikailo, 1975. Cytokine expression was studied in both primary and secondary infections using a semi-quantitatie RT–PCR technique.

用半定量RT-PCR的方法，研究初次感染和二次感染体外寄生的单殖吸虫---三代虫后，虹鳟鱼苗的皮肤中促炎症细胞因子IL-1β及IL-1βII型受体（IL-1RII）的特异性基因表达。

Specific gene expression of the pro-inflammatory cytokine IL-1β and the type II IL-1βreceptor (IL-1RII, 'decoy receptor') was studied in skin of rainbow trout Oncorhynchus mykiss (Walbaum, 1792) fry during infection with the ectoparasitic monogenean Gyrodactylus derjavini Mikailov, 1975. Cytokine expression was studied in both primary and secondary infections using a semi-quantitative RT–PCR technique.

用半定量RT-PCR的方法，研究初次感染和二次感染体外寄生的单殖吸虫---三代虫后，虹鳟鱼苗的皮肤中促炎症细胞因子IL-1β及IL-1βII型受体（IL-1RII）的特异性基因表达。

The treatment group was given Qizhengxiaotong Emplastrum(0.75 g/kg),and the model group and blank group were given normal saline solution(0.5 mL/each)externally for 5 days on 10th day after the establishment of ...

末次给药后测量各组小鼠的痛行为，包括机械性痛觉超敏和热刺激痛觉过敏；将小鼠股骨进行X线摄片，影像学评估骨破坏；用免疫组化法检测各组局灶皮肤组织肿瘤坏死因子α、内皮素-1(ET-1)、白介素-1β(IL-1β)水平及脊髓后角P物质受体、c-fos及GFAP阳性反应神经元的表达。

This paper first discusses the theory of commercial bank credit management, then, brings forward the theory innovation that evaluates the performance of commercial bank credit management, analyses actualities of evaluating the performance of commercial bank credit management in home or fremdness.

本文在研究方法上，第一次把因子分析法运用在商业银行信用管理绩效评价中，并通过理论研究与实证分析形成统一整体，同时还采用了归纳分析法、比较分析法等研究方法。

Several anti-tumor cell lines and carbonic anhydrase Ⅱ model were established. More than 10000 compounds and extracts from plants were screened using these models and about 10 compounds showed strong inhibitory activities. Two species of plants Inula helianthus-aquatica and Saussurea deltoidea were chosen to investigate chemical and bioactivity constituents based on the results of screening of extracts and fractions. 58 compounds were isolated and identified from these two plants, 6 compounds were found to be new and 14 compounds showed anti-tumor activities. We also studied the anti-tumor mechanism of the compound bigelovin isolated from Inula helianthus-aquatica. Bigelovin was found with apoptotic activity against cell line U266 by lowering the amount of important transcription factor E2F-1 which inhibits the cell cycle at G0/G1 stage. Docking study on 7 natural new phenolic inhibitors of CA Ⅱ and 3D-QSAR study on 61 sulfonamide inhibitors of CA Ⅱwere also investigated. The calculated results were in good correlation with experimental results.

基于以上两种重要疾病和研究组方向，本论文工作开展了多个肿瘤细胞株和碳酸酐酶Ⅱ靶标模型的建立和筛选工作，累计筛选1万多个/次样品，发现10余个活性较强化合物；从粗提取物筛选结果中选取两种抗肿瘤活性强的菊科植物水朝阳旋覆花(Inula helianthus-aquatica)和三角叶凤毛菊进行了系统化学和活性成分研究，分离鉴定了58个化合物，发现6个新化合物和14个抗肿瘤活性化合物；通过合作对水朝阳旋覆花中活性较强的bigelovin进行了抗肿瘤作用机制研究，发现它可能是通过降低G2期重要的转录因子E2F-1，致使细胞周期阻滞在G0/G1期，引起多发性骨髓瘤U266细胞凋亡；开展了7个新的天然酚类CAⅡ抑制剂的对接研究和61个合成的系列磺酰胺类CAⅡ抑制剂的3D-QSAR分析，结果表明计算与实验一致。

Based on the fundamental theory of the cable-prestressed steel truss established in paper [1], the inversive iterative perturbation equations which can be used to determine the stiffeness of elements of the prestressed steel truss with elastic supports are put forward by using the principle of matrix perturbation and introducing the concepts of the combined elements and stiffeness factors.

本文基于文献[1]所建立的拉索式预应力钢桁架基本理论，通过引入组合单元和刚度变化因子，利用矩阵摄动原理建立了以结点竖向位移为约束，以确定弹性支承多次张拉预应力钢桁架各类单元刚度为目标的反演摄动迭代方程。

We have measured the 〓for some proton rich nuclei at intermediate energies on RIBLL. A larger enhancementof 〓 for 〓 has been observed than for its neighbors. The anomalous enhancementin the difference factor d for 〓 compared to its neighboring nuclei and the longtail of the proton density distribution extracted from the measured 〓 support theassumption of the proton halo structure in 〓.

我们在RIBLL上实验测量了中能区一些丰质子核在〓靶上的核反应总截面，第一次从反应截面的角度观察到〓的〓有较大的反常增加，同时通过差异因子的分析及从实验数据中提取核子的密度分布得出〓的质子密度分布有很长的尾巴，即得到了〓具有质子晕结构的实验证据。

The single factor tests and orthogonal experimental designs were applied to optimize the extraction conditions for the crude polysaccharides from Marasmius androsaceus.

通过单因子和正交实验确定安络小皮伞菌丝体粗多糖提取的最优条件为：料水质量体积比1∶30、提取温度70℃、提取时间2h、提取次数1次，在此条件下粗多糖的提取率达到11。

Objective To investigate the effect of 8 Hz infrasound on the expression of brain derived neurotrophic factor in the rat hippocampus.

目的研究频率为8 Hz，声压级分别为90，100和130 dB的次声作用对大鼠海马脑源性神经营养因子表达水平的影响。

Singer Leona Lewis and former Led Zeppelin guitarist Jimmy Page emerged as the bus transformed into a grass-covered carnival float, and the pair combined for a rendition of "Whole Lotta Love".

歌手leona刘易斯和前率领的飞艇的吉他手吉米页出现巴士转化为基层所涵盖的嘉年华花车，和一双合并为一移交&整个lotta爱&。

This is Kate, and that's Erin.

这是凯特，那个是爱朗。