横纹肌肉瘤

Some of the laryngeal MFH were difficult to be differentiated from carcinosarcoma, pleomorphic rhabdomyosarcoma , myxoid liposarcoma ,malignant neurilemmoma and myxoma without immunohistochemical aids .

喉恶性纤维组织细胞瘤常规组织学与癌肉瘤、多形性横纹肌肉瘤、粘液型脂肪肉瘤、恶性神经鞘瘤、粘液瘤有时易混淆，免疫组织化学有助于明确诊断。

Clinical diagnostic considerations ranged from benign entities such as rhabdomyoma, intramuscular lipoma, fibromatosis, myositis ossificans, proliferative myositis, inflammatory myofibroblastic tumor, and inflammatory myopathy to malignant entities such as rhabdomyosarcoma, leiomyosarcoma, liposarcoma, and lymphoma.

这些病例的临床考虑多样，有良性的横纹肌瘤、肌内脂肪瘤、纤维瘤病、骨化性肌炎、增生性肌炎、炎性肌纤维母细胞瘤和炎性肌病，也有恶性的横纹肌肉瘤、平滑肌肉瘤、脂肪肉瘤和淋巴瘤。

Of the rhabdomyosarcoma cases, 34 of 51 (67%) ARMS were immunoreactive whereas none of the 55 embryonal rhabdomyosarcoma cases stained.

横纹肌肉瘤病例中，51例ARMS中有34例（67%）染色阳性，而55例胚胎性横纹肌肉瘤无一例表达。

Objectie To explore the relationship between the expression of oncoprotein, proliferating cell nuclear antigen, histological type, degree of differentiation, recurrence and metastasis in rhabdomyosarcoma.

目的 探讨横纹肌肉瘤癌基因蛋白和增殖细胞核抗原的表达与横纹肌肉瘤的类型、分化程度和复发、转移的关系。

The expression of C-myc is widely high in Rhabdomyosarcoma of female genital system, and the high expression has relationship with tumor＇s histological grade and prognosis.

结论C-myc在横纹肌肉瘤中普遍高表达，并与肿瘤组织学分级和预后相关；在横纹肌肉瘤中，C-myc的表达可能不依赖Ras-MAPK途径调控。

To search for the significance of immunohistochemical markers for the differential diagnosis of rhabdomyosarcoma and the clinical impact of different subtypes of rhabdomyosarcoma on prognosis.

目的 ：探讨横纹肌肉瘤的诊断和鉴别诊断中免疫组织化学标记的意义及不同类型横纹肌肉瘤对预后的影响。方法：应用病理形态学和免疫组化方法对 47例横纹肌肉瘤进行研究。

Results Among the 52 cases, 30 cases were confirmed to fibrosarcomas, which were identical with primary dingnoses;22 cases were revised to malignant fibrous histocytoma (8 cases), malignant nerve sheath tumor (4 cases), monophasic spindle cell synovial sarcoma (3 cases), leiomyosarcoma(3 cases), rhabdomyosarcoma(2 cases) and abdominal desmmoid tumor (2 cases). Of the 18 cases, only two cases were misdiagnosed and were revised to malignant fibrous histocytoma and spindle cell synovial sarcoma, respectively.

结果：1980年前52例中维持原诊断30例，修改诊断22例(42.3%)，分别为恶性纤维组织细胞瘤8例、恶性神经鞘膜瘤4例、单相性梭形细胞滑膜肉瘤3例、平滑肌肉瘤3例、横纹肌肉瘤2例、韧带状纤维瘤2例；1980年后纤维肉瘤18例中，维持原诊断16例，修改诊断2例(11.1%)，分别为恶性纤维组织细胞瘤和滑膜肉瘤各1例。

There were 22 malignant tumors including 11 osteosarcomas, 5 chondrosarcomas, 2 malignant fibrous histocytomas, and one each of malignant osteoblastoma, alveolar sarcoma, rhabdomyosarcoma, malignant giant cell tumor of bone. 28 benign tumors included 27 giant cell tumors of bone and 1 benign fibrous histocytoma.

肿瘤类型：恶性肿瘤22例，其中骨肉瘤11例，软骨肉瘤5例，恶性纤维组织细胞瘤2例，恶性骨母细胞瘤、腺泡状肉瘤、横纹肌肉瘤、骨巨细胞肉瘤各1例；良性肿瘤28例，其中骨巨细胞瘤27例，良性纤维组织细胞瘤1例。

The most common histologic type of SC was rhabdomyosarcoma (n=24), followed by high-grade unclassified sarcoma (n=5), rhabdomyosarcoma admixed with high-grade unclassified sarcoma (n=2), angiosarcoma (n=1), and low-grade myxoid sarcoma (n=1). Clinical follow-up information was available for 27 patients.

SC最常见的组织学类型是横纹肌肉瘤（24例），其次为高级别未分类肉瘤（5例）、横纹肌肉瘤与高级别未分类肉瘤混合（2例）、血管肉瘤（1例）和低级别黏液样肉瘤（1例）。27例有随访信息。

Very rarely, features of high grade osteosarcoma, leiomyosarcoma, chondrosarcoma, rhabdomyosarcoma and malignant peripheral nerve sheath tumor are found.

罕见的情况下可以找见高级别骨肉瘤、平滑肌肉瘤、软骨肉瘤、横纹肌肉瘤和恶性外周神经鞘膜瘤的特征。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。