模拟实验

Linear solvation energy relation was firstly introduced in the paper, and the method and step of gaining the special parameters of solvent and solute were introduced in detail, and these special parameters were used to selection and optimization of extractive agent in extractive distillation. The model of predicting activity coefficient at infinite dilution was established by linear solvation energy relation. By the above theory, several candidate solvents were selected to separate C5 fraction, and by experiment of vapor-liquid phase equilibrium at atmosphere pressure, the mixture of N-methyl-pyrrolidone including 4% water was used extractive agent of separating C5 fraction. Then binary vapor-liquid phase equilibrium of the some compound in C5 fraction and N-methyl-pyrolidone were determined at atmosphere pressure and correlated by NRTL equation. Isoprene being objective compound, experiments were operated in the laboratory-scale column; the processes were simulated by RadFrac model in ASPEN PLUS. And by the combination of experiment and simulation, the new process of separation of C5 was established.

本文首先对线性溶剂化能关系进行了分析介绍，也介绍了采用溶剂化能关系得到溶质溶剂特性参数的方法步骤，并将这些参数用于萃取精馏萃取剂的选择与优化；也通过线性溶剂化能关系式建立无限稀释活度系数预测模型，取得了一定的预测精度；将通过上述方法初选的溶剂进行了常压汽液平衡的测定研究，通过实验研究选定含水4%的N-甲基吡咯烷酮溶液做为C5分离的萃取剂，测定了大量N-甲基吡咯烷酮与C5组分的二元平衡数据，并进行关联计算；以异戊二烯为目标产物在实验室规模的精馏塔内进行了C5分离的实验研究，取得大量塔内数据；通过选用合适的热力学模型，采用ASPEN中RadFrac模块对分离过程进行模拟研究，通过实验与模拟相结合，建立了C5分离的新工艺，为将来的工业化打下了坚实的基础。

As tail-suspended rats model can form an abnormal model of lipid metabolism as well as bone metabolism, We added three levels offish oil to the diets of rats of this model to determine the effects of n-3 polyunsaturated fatty acids on lipid and bone metabolism, so as to determine the interaction of these two chronic diseases and clarify the mechanism of these diseases.

尾部悬吊模拟失重大鼠模型能够同时造成大鼠脂质代谢与骨代谢失调，而应用此模型进行脂质代谢与骨代谢失调相关关系及膳食(n-3)多不饱和脂肪酸干预对模拟失重条件下脂质与骨代谢的影响的研究尚未见报道。本实验通过添加以鱼油为来源的不同剂量的(n-3)多不饱和脂肪酸作为膳食干预手段，研究其对模拟失重条件下构建的大鼠脂质代谢与骨代谢异常的调节作用，以加强对脂质代谢与骨代谢相互作用生理进程的深入了解为目标，为阐明中老年人群慢性疾病并发或多发的生理生化机制提供一定的实验依据。

The paper includes three parts: to design a tactile based simulated phosphene positioning system; to study the characteristic of simulated phosphene positioning based on the system; to consider experimental related psychophysical problems in order to set up a scientific training procedure.

本课题包括三个方面内容：建立基于触觉的模拟光幻视定位系统；在该系统上设计一系列科学实验来研究模拟光幻视点定位的特性；研究与实验相关的心理物理学问题，建立一套完善的模拟光幻视定位的训练方案。

Three dimension modeling technique includes three dimension finite element method, three dimension photoelasticity experiment method and modeling with other materials.

该技术包括三维有限单元计算数值模拟、三维光弹实验模拟和其它材料的工程实验模拟技术。

At last the result of a RIE process at a certain condition is compared with the results of simulation, the result of Lag effect is compared with result of simulation, the results of multiple processes are compared with the results of simulation, respectively, and they fit well.

最后比较了一定条件下的刻蚀结果和模拟结果，比较了Lag效应的实验结果和模拟结果，比较了多道加工工艺结合的实验结果和模拟结果，两者吻合的较好。

The regulation of gene expression is to have relations to the assembly of the DNA binding proteins which bind to DNA to initiate the transcription. Some of these proteins have the ability to promote bending or looping of DNA. The FIS protein regulates gene expression in Escherichia coli by this property of bending DNA. There are many researches to discover the mechanism of FIS protein binds to DNA. However the experiment data only show the supposititious results and figure out the model of FIS-DNA complex structure. This research uses molecular dynamics simulation to compute the detail of the interaction between FIS and DNA. We observed FIS prominently affects the DNA bending by the type of local bending. Analyzing the DNA structure properties, roll and slide, also demonstrates the local bending type and region. The hydrogen bonds between FIS and DNA are analyzed to compare with the experiment data. Finally we compute the binding free energy between FIS and DNA to estimate the result of simulation and compare with the value of λ-repressor-DNA complex.

基因的表现与结合於DNA促使DNA转录作用起始的DNA结合蛋白组装有关，一些这类的蛋白质具有促使DNA扭曲或将DNA形成环状的能力，FIS蛋白质即是藉由扭曲DNA的特性调控大肠杆菌基因的表现，目前已有很多的研究发现FIS与DNA结合的机转，然而这些实验的数据仅能显示推测性的结果，进而利用这些结果推论出FIS与DNA聚合体结构的模型，本研究利用分子动态模拟的方式计算FIS与DNA交互作用的细节，我们观察到FIS主要影响DNA的扭曲方式为DNA区域扭曲的类型，并且分析DNA结构特性roll与slide也指出扭曲方式为区域扭曲与其扭曲的区域，我们也分析FIS与DNA之间的氢键，并且与实验的资料作比较，最后我们计算FIS与DNA之间的结合自由能评估模拟的结果，并且计算出的值和λ-repressor与DNA聚合体结构的实验值作比较。

This article mainly simulates gradually damage destruction process of rock, major in determinationg the definition of rock three-dimensional damage tensor, simplify to the damage tensor and obtain its engineering calculation method, and obtains the basic expression form of equivalent stress by equivalent stress assumption, symmetrization to the actual stress, thus obtains construction relation of the festival principle of three-dimensional damage rock mass, finally couples elasticity- plasticity with damage in the finite element equation, with reference to elasticity-plasticity gradually degenerated method thought, simulates rock damage to advance gradually the destruction process in finite element method, draws up elasticity - plasticity and damage coupling two-dimension finite element procedure with the C language in the VC contact surface, by simulating experiment destroyed process, acquires destruction image and the axial load distortion curve of model, agreement with the experimental result.

本文主要模拟岩石渐进损伤破坏过程，确定岩石三维损伤张量的定义，对损伤张量进行简化计算并得出其工程计算方法，采用等效应力假设得出有效应力的基本表达形式，对有效应力进行对称化，得出节理损伤岩体的三维本构关系，在有限元方程中实现弹塑性和损伤耦合；借鉴弹塑性渐进退化方法的思想，采用有限元的方法模拟岩石损伤渐进破坏过程，用C++语言在VC界面编制了弹塑性和损伤耦合的二维有限元程序，通过模拟已有的实验破坏过程，得出模型的破坏图像和轴向荷载变形曲线，与实验结果基本一致。

Hot-humid climatic wind tunnel paper introduced can simulate above natural climate environmental elements according to the variant velocity of flow and simulated solar radiant intensity regulation.

介绍的动态热湿气候动态风洞实验台，在传统风洞风速模拟与控制实验技术基础之上，通过增加太阳辐射模拟和空气温湿度控制，初步实现了对室外自然气候中太阳辐射、风速及温、湿度环境的模拟控制。

The statistic results show that the cost of experiments doubled every ten years because the price of the laboratory apparatus and the cost of labor force increase. On the other hand, the cost of computer simulation decreases due to the improvements of the computer hardware and software technology. Thus more and more researchers focus their interests on the technology of computer simulation.

近年来随着实验仪器、劳动力成本的增加，人们做实验的花费也随之成倍增长，据估计每过十年实验的成本就要翻一番，另一方面，采用计算机来模拟实际体系的成本却随着计算机硬件和软件技术的进步而不断下降，因此分子模拟技术越来越受到相关领域研究人员的关注。

Ompare the experimental results with analytical results and sum up the factors which affect the flow front of underfill to find the method which can control the flow front, reduce the chance of short shot and air trap; therefore, enhance the reliable of underfill process of Flip-Chip.

AE(Computer-Aided-Engineering)模流分析模拟其流动情况；在完成实验与分析模拟之后，进行实验与模拟结果比较，归纳出影响底部充填波前形状的因素，并寻求控制底部充填流动波前形状的方法，降低短射与包风的发生，提高覆晶底部充填制程的可靠度。

She gently rebuff ed him, but agreed that they could be friends

她婉言拒绝了，但同意作为朋友相处。

If in the penal farm, you were sure to be criticized.

要是在劳改农场，你等着挨绳子吧！