模型眼

METHODS: Adult male Wistar rats, 9 weeks of age, were injected intraperitoneally with STZ to create diabetes. At 2 week after the models were created, BDNF protein was administered into the vitreous cavities of rats. At 4 week after the models were created, the rats were killed and the retina was removed for Western blotting and Whole-mount immunohistochemistry for TH to observe the changes of TH and dopaminergic amacrine cells in retina.

9周龄Wistar大鼠，链脲佐菌素（streptozotocin，STZ）腹腔注射，制成糖尿病模型，于模型建立2wk后，大鼠眼玻璃体内注射BDNF溶液，于模型建立4wk后，处死大鼠，取出眼球，取视网膜组织进行Western blotting及视网膜铺片免疫组织化学染色检测，观察视网膜中TH水平的变化，从而反映糖尿病大鼠视网膜中多巴胺能无长突细胞水平的变化。

The simulation results demonstrate the rightness and efficiency of FEM. Based on the studies above, the detective characteristics of FMI are examined, a few device structural parameters are numerical analyzed and optimized. The response of each type of formation model is simulated, and gray-scale images are used to express the resistivity results. Adopting 8 electrodes manner to measuring inclined bed, a full-bore resistivity image is obtained, and the relations between the image and the inclined bed are pointed.

在上述工作基础上，考察了全井眼地层微成象仪的探测特性；对有可能影响测量结果的仪器结构参数进行了分析和优化；模拟各种地层模型的测井响应，并用灰度图象表示电阻率井壁成象结果；采用8极板同时测量的方式，对倾斜地层进行模拟测量，得到了全井眼电阻率成象结果，并指出了成象特征与地层倾斜方向之间的关系。

This article that focuses on the systematic and in-depth research in the current primal problem about abnormal burst pressure reservoir depress burst pressure has procured following main fruits:1 It forms the method which could obtain massive vertical static state mechanics parameters.2 In a foundation of acquisition of rock mechanics parameters,apply bent lamella that as mechanical model along with characteristic of actual geologic characteristics to analysis curvature for anticlinal strcture, get homologous tectonic stress value throug relation between the curvature and stress and different principal curvature in anticlinal structure,consequently set up laminational stress model for anticline reservoir. The block lamination for existed fracturing date has formed method of setting up mechanical model of lamination terrestrial stress by abtaining the block tectonic stress coefficients which are got by complex utilization test, laboratory test and fracturing date playback.3 Analysesing the main reason which lead to high burst pressure by considering the characteristic of reservoir geology,reservoir,and rock mechanics and reservoir damage,etc.Establishing burst pressure quantitative prediction model which provide gist for depressing construction risk and optimizing construction craft under the condition of open hole completion ,gun-perforated completion and damaged reservoir.4 Provding theoretical basis for interpreting acidification pretreatment which could depress busrt pressure by finding the relation between the influencing factors and rock machanics parameters and analysing the factors that have effect on rock mechanics parameters. Expounding the mechanism of reaction of mixed monomineral and acid from the angle of microcosmic element, evaluating quantitatively acid sensilility of different kinds of mineral effectively, and determing the first-order reaction dynamical equation of each mineral.5 Revealing rock mechanics property chage as a result of acid flooding in different condition by sandstone traumata experiment in different temperatures which combined with rock mechanics triaxial stress experiment.6 Associating damage mechanics with sandstone acidizing, established sandstone damage mechanics model in the foundation of the recognition on the rock mechanics parametric variation which is caused by acid-rock reaction in both macroscopic view and microscopic view ,also demonstrated those processes and quantitative estimated the acid busrt pressure to direct the site operation.

本文针对目前异常破裂压力储层降低破裂压力的主要问题展开较为系统和深入的研究，取得了以下主要成果：1形成了利用测井资料，结合室内岩芯测试结果，获取静动岩石力学参数的相关性特征，从而获得纵向上大量静态力学参数的方法。2在获取了岩石力学参数的此基础上，利用弯曲薄板作为力学模型，结合区块实际地质特征对背斜构造进行曲率分析，通过曲率与应力的关系，利用背斜构造不同部位的主曲率求得相应的构造应力值，从而建立起背斜储层的分层应力模型；对已有压裂资料的区块分层，形成了综合利用测试、室内实验、压裂资料反演获得该区块构造应力系数，建立起分层地应力的力学模型的方法。3综合考虑储层地质、油藏、岩石力学特性和储层伤害等因素，分析造成高破裂压力的主要原因，综合利用岩石力学、弹性力学等知识，建立了裸眼完井、射孔完井条件下以及储层受到伤害后的储层破裂压力定量预测模型，为降低施工风险和优化施工工艺提供了依据。4完成了物性、岩性影响岩石力学参数的因素分析，找出了各影响因素和岩石力学参数之间的关系，为从机理上解释酸化预处理降低破裂压力提供了理论基础；从微观元素的角度阐述了单矿物与酸反应的机理；并在此基础上，有效评价了各种矿物的酸敏感性，定量确定了岩石中各矿物的一级反应动力学方程。5完成了不同温度下的酸液类型、酸液浓度、注酸量等一系列砂岩损伤实验，结合岩石力学三轴应力实验，系统揭示了在不同条件下注酸而引起的岩石力学性质变化。6将损伤力学与砂岩酸化相结合，在宏观、微观两个方面认识酸岩反应引起岩石力学参数变化基础上，建立了砂岩损伤力学模型，并对其进行验证，在此基础上定量计算酸化后的破裂压力，有效指导现场施工

In our study, the approach of the chorioretinal venous anatomosis in the model eyes with branch retinal vein occlusion, are induced by different surgical anastomosis procedures, in order to invest the effectiveness and safety and make a pilot clinic treatment exploration.

对照组：用眼内电凝方法建立兔眼的视网膜分枝静脉阻塞模型：单纯穿刺吻合组：在建模完成后，用200针直接穿刺切开距阻塞点以远2/3一IPD的淤滞状态静脉管壁和其下方的视网膜和Bruch's膜；吻合联合不吸收材料植入组：在同Ta组选定的吻合部位，用MVR刀切开视网膜和Bruch's膜和静脉管壁，在视网膜切口植入一小段7一0 prolene不吸收缝线。

In view of the destructional problem of open-off cut , the type of open-off cut surrounding rockmass is summed up and the basic model of open-off cut surrounding rockmass is obtained.

针对目前切眼围岩破坏的问题，对切眼围岩类型进行总结，得出切眼围岩的基本模型。

IOP was elevated by electrocoagulation of at least 3 episcleral and limbal veins in the right eye of each rat in the ocular hypertension group.

采用电凝鼠眼巩膜表面至少三组静脉及角膜缘周围血管，减少房水静脉回流建立鼠眼青光眼模型。

Methods］ 36 twomonthold rabbits with white feather and black eyes,half male and half female,were randomly divided into 6 groups:normal group,model group,xiangsha liujun pill group, lizhu changle group, lowdose leweiyintreated group,highdose leweiyintreated group.except the normal group, others were made into ibs model of spleen deficiency which was induced by damp heat stress and gavage with fanxieye as well as method of either hunger or gorge.the drug groups were administered preventively from the mediumterm of the model reproduction to the end of modeling.the rabbits of each group were observed.no,nos,mda,sod in serum and sp in colonic membrane were detected.

方法］两月龄白毛黑眼兔36只，雌雄各半，随机分为6组：正常组、模型组、香砂6君丸组、丽珠肠乐组、乐胃饮低剂量组、乐胃饮高剂量组。除正常组外，其余whbe兔采用湿热环境应激联合番泻叶灌胃加饥饱失常复合方法致脾虚泄泻型ibs模型。从模型复制的中期开始各用药组预防给药，至造模结束。观察各组1般情况，测定血清no、nos、mda、sod含量及结肠黏膜组织中sp含量。

Elaborated the punching components formation principle, the basic dies structure and the rate process and the principle of design; and designed some conventional punching die:the die for big diameter three direction pipe which solved the problom of traditional machining,the drawing and punching compound die with float punch-matrix,代写医学论文,the drawing and cutting compound dies with unaltered press,the compound die for the back bowl of the noise keeper,the design of the compound die which could produce two workpieces in one punching,the bending die for the ring shape part ,the bending die which used the gemel ,automate loading die for cutting, the drawing,punching and burring compound dies with sliding automated loading,the punching die for the long pipe with two row of hole,the drawing die for the square box shape workpiece and the burring die for the box shape workpiece.

本文对于冷冲压技术的分类、特点及发展方向作了简略概述；论述了冲压零件的形成道理、基本生产模型结构与运动历程及其设计道理；对于典型的冲压件生产模型进行了设计：大直径三通管冲压复合模设计盖世了大直径三通管的加工难题、带有浮动凸凹模的拉伸冲孔复合模设计、适力压边式落料拉伸切边复合模设计、消音器后补碗落料、拉深、冲孔、翻边复合模设计、一模两件落料拉伸冲孔翻边复合模设计、环形屈曲件的生产模型设计、铰链卷圆成形工艺及生产模型设计、半自动送料切角装置设计、滑板式送料拉深、冲孔、翻边模设计实现自动送料、长管多孔冲模设计、带凸缘台阶方盒形零件拉深模以及盒形件侧壁孔眼翻孔模。

Improving vertical resolution for density curves is by means of restructuring the response from large and small spacing sondes and borehole effect correction factor and coherence factor are used. Form the principle of GR logging, calculate volumes in investigating areas taken by borehole, formation, up and low shoulder beds, along with distance between center of gravity of the four unit bodies and detector. Based on the above, the weighting function of each unit body to GR signal contributions are established, thus realizing processing of GR logs with high resolution. The resistivity logging model uses "resolution matching" method to improve the resolution of the logs. After the process, PNN model is made to recognize the oil-gas-water bed. Compared with BPNN, the net work is featured swiftness, accuracy and ease of practical application.

提高密度测井曲线垂直分辨率是通过对重新组合长、短源距探测器响应的算法来提高补偿密度曲线的垂直分辨率，并加入井眼影响校正因子和相关性因子；自然伽马测井模型从基本原理出发，扣除井的影响，计算井筒、地层及其上下围岩所占探测球域体积及其重心到探测器的距离，以此建立各单元体对伽马测井信号贡献的权函数，通过权函数逐层计算不同厚度地层条件下各的单元体权因子，实现自然伽马曲线高分辨率处理；电阻率校正模型应用&分配率匹配&模型，应用低分辨率曲线提高为高分辨率曲线：曲线校正后，利用常规测井资料并且结合校正后的密度、伽马、电阻率等三个对判断油水层有利的指标，通过概率神经网络模型识别储层流体性质，较以前的模型，不仅极大的提高识别正确率，同时与普通神经网络相比较，提高了网络的运行速度和实用性。

When I'm satisfied with the general volume a shell modifier helps me to give thickness to the piece. In this phase, I don't usually bother that much about every single rivet, hole or cut, I just try to develop a good quad topology of the main volumes. Of course the topology is done by taking count of the main cuts and holes, but the rest can be done easily with a normal or bump map. It's up to you to decide how much a single detail is worth to be modeled or can it be put into a bump map. I usually adopt a "comfortable" criteria...it means that if something looks tricky to me to be carved or extruded into an existing geometry I usually put it into a normal map. When you make something for production, you don't usually have much time to model everything, so you need to set priorities.

当我对整个盔甲的体积感满意之后，一个shell修改器就可以帮我给整个盔甲添加厚度，在这个阶段，我通常不会考虑太多那些细小的铆钉，洞眼或者切边，我只是给整个的模型确立一个好的四边形拓扑结构，当然拓扑是通过重视主要的切割和打洞来形成的，但其余那些细小的部分可以用一个normal 或者bump贴图很容易地模拟出来，这由你来决定到底一个细节是值得建模还是放到一个bump贴图里面，我通常采用一个&舒服&的标准，也就是说，如果有什么东西对我来说，在已有模型上再挤出或者开洞是非常麻烦的，那么我就通过Normal贴图来表现，而当你为商业生产制作模型时，你通常都没有足够的时间来把任何东西都建出来，因此你需要设置重点。

As she looked at Warrington's manly face, and dark, melancholy eyes, she had settled in her mind that he must have been the victim of an unhappy attachment.

每逢看到沃林顿那刚毅的脸，那乌黑、忧郁的眼睛，她便会相信，他一定作过不幸的爱情的受害者。

Maybe they'll disappear into a pothole.

也许他们将在壶穴里消失