棘细胞

Pathological changes of the organization, mainly the epidermal cuticle significant parakeratosis, acanthosis cell layer thickening, epidermal sudden downward extension of in-depth dermis.

本型组织病理改变，主要是表皮角质层有显著角化不全，棘细胞层增厚，表皮突向下延展，深入真皮。

He positive cells of TIMP-2 were observed in the prickle and basal layers.

IMP-2在基底细胞层和棘细胞层有少量表达；我了解到了那令人恐惧的事实，顿时感到不寒而栗

Results The expressions of IGF IR protein and mRNA were located on the basal cell layers and prickle cell layers.

结果IGFIR蛋白与mRNA表达在银屑病患者基底层和棘细胞层，IGFIR蛋白与mRNA相对积分光密度值在正常对照组与银屑病组间存在极显著性差异（P＜0.01）。

Spinous layer: the innermost prickle cells are polygon, and from the inside to outside, they become more and more flat, they are connected to granular cells with some space between, besides the spinous process, under normal condition, there is cell tissue fluid that could help the metabolism of cells in between.

棘层：棘细胞自里向外由多角形渐趋扁平，与颗粒细胞相连，各细胞间有一定空隙，除棘突外，在正常情况下，还含有细胞组织液，辅助细胞的新陈代谢。

No expression of WAF1 /CIP1 mRNA in normal skin of 4 individuals, and overexpression of WAF/CIP1 mRNA in lesional psoriatic epidermis of 28 cases were observed.

发现WAF1／CIP1mRNA在4例正常对照皮肤中不表达，在28例银屑病患者表皮中呈高表达，WAF1／CIP1mRNA主要在银屑病患者表皮棘细胞层上部和颗粒层细胞中表达，在基底细胞层则基本不表达。

From the outside to the inside , the body skin is divided into the stratum corneum , stratum lucidum , stratum granulosum , stratum spinosm and stratum basale , after through stratum corneum , stratum lucidum , stratum granulosum , stratum spinosm EGF can reach the stratum basale: accelerate the basal cells prpliferation and differentiation , reverse matured cells' differentiation to make stem cells that will form a " stem cells island " with a certain amount , which accelerate the generation of new cellls , make senescent cells keratinize and shed rapidly , make broken and denatured collagen fibers and elastic fibers repaired , so the skin's elasticity increase , and the wrinkles calm down or disappera gradually .

体表皮由外及里共分为角质层、透明层、颗粒层、棘细胞层、基底层，EGF可以通过透明层、颗粒层、棘细胞层深入肌肤基底层，加速基底层细胞增殖分化，将已经分化成熟的细胞逆分化成干细胞，当达到一定量时，便会形成&干细胞岛&，加速新细胞的生成，让衰老细胞快速角化、脱落，已断裂、变性的胶原纤维和弹性纤维得到修复，皮肤弹性增加，皱纹逐渐平复、消失。

Results There were 52 cases (63%) of LA and 30 cases (37%) of MA, among which 49 cases (60%) presented with pyknotic nucleus of the basal keratinocytes above the amyloid in the upper dermis and 18 cases (22%) presented with pagetoid dyskeratosis cells among their prickle cells. More amyloid in LA and more severe incontinent of pigment in MA.

结果 82例患者中，52例(63%)为LA，30例(37%)为MA；有49例(60%)在淀粉样蛋白沉积上方基底细胞内出现核固缩现象；18例(22%)棘细胞层出现帕杰样角化不良细胞。

RESULTS: Transplanted AS had a favorable fusion between tissue-engineered skin and self-skin on the 3rd day after grafting with a few of ingrowths of capillaries.

结果：AS组在移植第3天，移植的组织工程皮肤与自体皮肤能够很好地融合，有少量毛细血管长入移植物，皮肤移植物颜色与自体皮肤颜色接近；随着时间的延长，移植物中毛细血管的数量逐渐增多，表皮层清晰可见基底层、棘细胞层、颗粒层和角质层，角化现象加强，有角化物脱落；真皮层细胞数量增多，网架逐渐降解，分泌的细胞外基质成份增多；第14天，创面基本愈合；修复区皮肤颜色与正常皮肤颜色非常接近，瘢痕很小，无需进行二次植皮。

In head and neck cancer positive cells that were general 3～5 layers looked like a band in the basilar part and prickle cell layer.

头颈部恶性肿瘤中elF4E阳性细胞在受累的鳞状上皮层呈带状分布于基底层及相邻的棘细胞层，一般为3～5层。

HPV was also detected in the granular ladyer and whole prickle cell layer of 11 cases of CA with no typical koilocytes.

鼵A中，10例具典型组织学特征的CA均有HPV分布，主要位于表皮浅层，另 11例缺乏典型空泡细胞的 CA在颗粒层或棘细胞全层测得 HPV。

With Death guitarist Schuldiner adopting vocal duties, the band made a major impact on the scene.

随着死亡的吉他手Schuldiner接受主唱的职务，乐队在现实中树立了重要的影响。

But he could still end up breakfasting on Swiss-government issue muesli because all six are accused of nicking around 45 million pounds they should have paid to FIFA.

不过他最后仍有可能沦为瑞士政府&议事餐桌&上的一道早餐，因为这所有六个人都被指控把本应支付给国际足联的大约4500万英镑骗了个精光。