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Furthermore, abnormal morphology, shrinkage and reduced density of dendritic spines and defects in LTP were observed in brains of the patients suffering from mental retardation and neurodegenerative diseases; many mutant genes found from these patients encode component proteins of signal transduction for neuronal plasticity. These studies on synaptic plasticity would certainly promote making the effective prevention and treatment procedures for mental and neurodegenerative diseases.

此外,在精神迟滞性疾病和神经退行性疾病患者脑内记录到异常的LTP,并发现神经元的树突棘数量减少,形态上产生畸变或萎缩,同时发现,产生突变的基因大多编码调节突触可塑性的信号通路蛋白,故突触可塑性研究也将促进精神和神经疾病的预防和治疗。

Results There were nNOS-immunopositive never endings in fibrous coat of capsule of cervical zygapophyseal joints, flava ligament, interspinalia ligament, supraspinale ligament and annulus fibrous of intervertebrale disc. These nerve endings present arborization or beads.

结果 人颈椎关节突关节囊的纤维层、黄韧带、棘间韧带、棘上韧带和椎间盘的纤维环内均有nNOS免疫反应阳性神经末梢的存在,这此神经末梢呈树枝状或念珠状,其走行与结缔组织层平行。

Because dendritic spines are the sites of connection between neighbouring nerve cells, the increased number may mean more activity in the fathers' brains than in those of the non-fathers.

由于树突棘是领近神经细胞之间相接触的地方,因此树突棘数量的增多可能意味着父绒猴大脑内的活动比非父绒猴的要多。

Tetanic synaptic stimulation induced a rapid delivery of tagged receptors into dendritic spines as well as clusters in dendrites.

强的突触刺激诱导标记受体迅速转移到树突棘和树突簇上。

Long-term modulation of spine density, but not number of primary dendrites, by BDNF was gated by cAMP.

研究表明,BDNF 对突触后树突棘密度的长时程作用也受cAMP 的门控调节,但是BDNF 对神经元一级树突数目的调节并不受cAMP 的调控。

NO takes part in transmission of sensation message among capsule of cervical zygapophyseal joints, flava ligament, interspinalia ligament, supraspinal ligament and annulus fibrous of intervertebrale disc.

结论一氧化氮参与人颈椎关节突关节囊、黄韧带、棘间韧带、棘上韧带和椎间盘的纤维环等结构的伤害性感觉信息的传递。

NO takes part in transmission of sensation message among capsule of cervical zygapophyseal joints, flave ligament, interspinalia ligament, supraspinal ligament and annulus fibrous of intervertebrale disc.

氧化氮参与人颈椎关节突关节囊、黄韧带、棘间韧带、棘上韧带和椎间盘的纤维环等结构的伤害性感觉信息的传递。

Spines were tested first intact, then after complete C5-C6 discectomy with posterior longitudinal ligament resection and ACDF with a wedged bone graft and a rigid locked plate, and finally after complete release of the supraspinous, interspinous, and intertransverse ligaments; the facet capsules; and ligamentum flavum.

首先在完整的颈椎上进行检测,此后将C5-C6椎间盘完全切除、后纵韧带切除后使用坚强锁定钢板及楔形植骨行ACDF,最后完全松解棘上、棘间、横突间韧带及关节囊和黄韧带,在上述情况下分别进行检测。

Under stimulation of glutamic acid, [Ca2+]i in soma increased from 100 nM to 1 μM, and [Ca2+]i in spines increased from 50 nM to 300 nM. These results prove that monitoring calcium concentration in spine with Cameleon is feasible.

吹加谷氨酸来研究了神经元的胞体和树突棘的钙动力学,在100 μM 的谷氨酸的刺激下胞体内钙离子浓度从100 nM 上升到1 μM 左右,而树突棘内钙离子浓度从50 nM 上升达到500 nM。

It can be used in studying the calcium dynamics, in addition it\'s applicable for real-time, less damage and long-playing observation. It might be important to study calcium of spine with stimulations of neurotransmitter and action potential.

结果表明,利用Cameleon 的FRET 比值变化来定量监测树突棘钙动力学的方法是切实可行的,并可以进行实时、无损、长时间的监测,为研究神经递质、动作电位等刺激对树突棘内钙信号影响提供一种重要研究手段。

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