棘手

It is a very tough and unpleasant work.

这是一份非常棘手而且令人不快的工作。

When the skin suffers to the serious burns, wound, infection and diabetes unprogressive skin ulcerates etc, it become hard problem to repair and rebuild the big area skin defect.

当皮肤遭受严重烧伤、创伤、感染及糖尿病顽固性皮肤溃疡等损害时，大面积皮肤缺损的修复成为棘手的难题。

By emphasizing the extraordinary he seeks to challenge his profession's often unreflective reliance on technology and restore the doctor-patient relationship, the touchy-feely human connection, to the center of medical practice.

通过强调非凡，他尝试挑战自己职业中关于科学技术的利用及医患关系的恢复中那些通常没有反馈的信赖；以及对于医疗实践中心而言，棘手的人际关系。

For these reasons,the following study work has been finished in this paper.(1)Basic equation of saturated-unsaturated seepage is built based on seepage continuity and motion Equations,which take saturation zone and unsaturation zone into account together and avoid difficult problems of traditional numerical solution,such as solution of free surface of seepage etc.

对此，本文主要完成了以下研究工作：(1)从渗流连续性方程和渗流运动方程出发，阐述了饱和—非饱和流统一的渗流基本方程，将饱和区和非饱和区统一来考虑就避免了求解渗流自由面等传统的数值求解的棘手问题。

But it is Annans destiny to be handed the very worst problems after they have been unsuccessfully addressed by others.

但是，安南注定要处理这些棘手的问题，而这些问题是由别人的失败造成的。

Fortunately, the overwhelming majority of us never run off the moral rails in remotely as awful a way as serial killers do, but we do come untracked in smaller ways.

"他者"对智人来说是一个棘手的概念。社会生物学作为一种过于简约的科学已被批判，它将所有生物的行为归因于只不过是一种让基因尽可能地流传到下一代的努力。

And the recent upturn may make it harder for political leaders to get their voters to understand this.

而近期的经济好转使得让选民们明白这一点对各国的政治领导者来说都是一个棘手的难题。

However, tricky to set up and not user-friendly.

然而，棘手的建立和并不方便。

With the developing of automachinism, skin trauma is more and more popular and the wound becames more and more complex, so it is harder to be treated, especially some patient with diabetes or varicosity.

随着交通、建筑等行业的快速发展，皮肤的外伤性创伤越来越多见，并且伤情越来越复杂，治疗起来更加困难，尤其是患者本身患有糖尿病、静脉曲张等疾病，其创面治疗更加棘手。

Numerous bacteria, viruses, and protozoa have been implicated as etiologic agents for NGU, although definitive proof for causation with most of these agents is lacking. Therefore, managing cases with recurrent or persistent NGU is one of the most difficult problems in venereology.

在临床上常见的是迁延不愈以及衣原体、支原体均为阴性的NGU患者，对于该类患者的治疗已成为性病学上较为棘手的问题，并引发了人们对于其他病因研究的兴趣。

She gently rebuff ed him, but agreed that they could be friends

她婉言拒绝了，但同意作为朋友相处。

If in the penal farm, you were sure to be criticized.

要是在劳改农场，你等着挨绳子吧！