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New antifungal agents have been developed over the past years based on the discovery of many new target sites of Candida albicands. For example, Echinocandins, aiming at the cell wall of Candida albicands, showed strong antifungal activities to fluconazole resistant candidas and fungal biofilm. Moreover, because β-glucan synthase does not exist on the cell membrane of mammalian cells, Echinocandins has a low toxicity and a promising clinical future. Though the mechanism of Histatin is not clear, it has strong activity not only on candida resistant of polyene and azole, but also to Candida parapsilosis, Candida krusei and Cry ptococcus neoformans. Berberine and Ocimum gratissimum L. were also found to have prominent anti-fungi activities.

近年来相继提出了许多抗白念珠菌药物作用的新靶点并成功开发出一些活性强大，疗效确切的抗真菌药，如以真菌细胞壁为靶点开发出棘白菌素类药物卡泊芬净、米卡芬净等，该类药物主要抑制β-葡聚糖合成酶，体外对氟康唑耐药的念珠菌属及真菌生物被膜表现出强大的抗菌活性，又由于β-葡聚糖合成酶在哺乳类动物细胞内不存在，故具有高效低毒的临床效果，是一极具前途的新型抗真菌药；以真菌细胞膜为靶点开发出Histatin类药物，虽然作用机制目前还不完全明了，但其作用不同于临床常用的多烯类和氮唑类，并已经发现Histatin5对两性霉素B和氮唑类耐药的念珠菌有效，并且对非白念珠菌如光滑念珠菌、克柔氏念株菌、隐球菌等也有杀灭作用；通过对植物药物的研究发现黄连素和丁香罗勒Ocimum gratissimum L。

Granulosus in Xinjiang and there was no nucleic acid sequence difference of Eg95 antigen among the protoscolex, oncosphere and adult worm of E. granulosus.

结论Eg95基因在新疆株细粒棘球绦虫不同发育阶段均有表达，其基因序列无差异。

Eg95 antigen cDNAs were amplified by PCR from protoscolex, oncosphere and adult worm cDNA libraries of E. granulosus, respectively and were cloned into pUCm-T plasmid, and sequenced. The sequences were analyzed by DNAman and GenBank/BLAST biosoftware.

方法根据Eg95基因序列设计引物，用PCR方法分别从新疆株细粒棘球绦虫3个不同发育阶段所构建的cDNA文库中克隆获得Eg95目的基因，将其克隆至pUCm-T载体、测序并进行序列分析。

As for the ovalization-curvature curve, it can be observed that the ovalization increases in a ratcheting manner with the number of the bending cycle. When the magnitude of the ovalization reaches a critical value, the tube buckles.

至於在椭圆化－曲度的曲线图中显示，椭圆化会随著循环弯曲的圈数渐增且呈现对称棘齿的变化，当椭圆化值增加到某一极限时，薄壁圆管便会发生皱曲破坏。

Owing to the progressive accumulation of the ovalization of the tube cross-section during cyclic bending, the tubes buckle eventually.

从椭圆化－曲度的实验曲线中显示，在对称曲度循环弯曲负载时椭圆化会渐增且呈对称棘齿的变化，椭圆化会一直增加直到钢管发生皱曲。

For the ovalization-curvature curve, the ovalization exhibits the unsymmetric-increasing ratcheting manner with the number of cycles. It is shown that the width does not affect the aforementioned curve, however, the deeper the sharp-notch, the larger amount of the ovalization to bend the tube to a certain magnitude of curvature.

至於椭圆化-曲度的曲线图中显示，椭圆化会随著循环圈数呈现非对称棘齿状的增加，而凹槽宽度对上述曲线没有太大的影响，但尖锐凹槽的深度越深，弯曲至某固定曲度时所产生的椭圆化量就越大。

Objective: To review literature data and investigate the method of process of extraction, of identification, and determination of content in polysaccharide of Oxytropis myriophylla.

目的：考察文献资料方法，探讨提取多叶棘豆中多糖，并鉴别多糖及含量测定的方法。

ICP-AES method was applied for the determination of the trace elements in Oxytropis Ochrocephala Bunge and for the analysis of the relationship between the contents of and its toxicology.

采用ICP-AES测定了黄花棘豆中的微量元素及其含量，分析了微量元素含量与其毒理学的关系。

New taxa of the genus Oxytropis DC. from China.

标题 中国棘豆属新分类群。

New taxa of the genus Oxytropis DC.

Title 中国棘豆属新分类群。

I didn't watch TV last night, because it .

昨晚我没有看电视，因为电视机坏了。

Since this year, in a lot of villages of Beijing, TV of elevator liquid crystal was removed.

今年以来，在北京的很多小区里，电梯液晶电视被撤了下来。