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Objective: To observe the effects of Cinnamyl aldehyde on NIH3T3 cell cycle and explore the possible mechanism further.

中文摘要:目的:观察肉桂主要成分桂皮醛对小鼠成纤维瘤细胞株NIH3T3细胞周期及相关蛋白的影响。

objective to determine the contents of eucalyptol, camphor, synthetic borneol, menthol, methyl salicylate, cinnamaldehyde and eugenol in shexiang qufengshi adhesive plasters by gc method.

目的建立气相色谱法同时测定麝香祛风湿膏中桉油精、樟脑、冰片、薄荷脑、水杨酸甲酯、桂皮醛、丁香酚等7组分的含量。

Results the resolution and linearity of eucalyptol, camphor, synthetic borneol, menthol, methyl salicylate, cinnamaldehyde and eugenol were good with the recovery rate of eucalyptol at 98.7 %(rsd=1.1 %) camphor at 99.0 %(rsd=1.0 %), synthetic borneol at 99.4 %(rsd=0.8 %), menthol at 99.7 %(rsd=0.4 %), methyl salicylate at 99.6 %(rsd=0.5 %), cinnamaldehyde at 99.5 %(rsd=0.8 %), eugenol at 99.5 %(rsd=0.9 %), respectively.

结果在该色谱条件下桉油精、樟脑、冰片、薄荷脑、水杨酸甲酯、桂皮醛、丁香酚的分离度和线性关系良好,平均回收率(n=6)分别为98.7 %(rsd=1.1 %)、99.0 %(rsd=1.0 %)、99.4 %(rsd=0.8 %)、99.7 %(rsd=0.4 %)、99.6 %(rsd=0.5 %)、99.5 %(rsd=0.8 %)、99.5 %(rsd=0.9 %)。

Chinese Cinnamaldehyde Cinnamaldehyde alias, Lauraceae plants are dry skin and cinnamon bark obtained by steam distillation of volatile oil in the main component of research in recent years are more root canal sterilization drug, it can seriously undermine the bacterial cell surface structure, and thus has a wider antibacterial spectrum and strong antibacterial activity; gallnut hundred, also known as worms, insect species are Schlechtendalia Schlechtendalia or times aphid eggs in their parasitic plants Anacardiaceae Rhus chinensis, Green bran Yang Yang, such as bran or red tree gall formation, the main ingredient for gallnut tannin, can solidification microbial protoplasts and a variety of body enzymes, a wide range of bacteria, fungi, yeasts are inhibited.

中药桂皮醛别名肉桂醛,是樟科植物肉桂的干皮及树皮经水蒸气蒸馏得到的挥发油中的主要成分,是近年来研究较多的根管消毒药物,它能够严重破坏细菌细胞表面结构,从而具有较广的抗菌谱和较强的抗菌活性;五倍子又名百虫,是倍蚜种昆虫角倍蚜或倍蛋蚜在其寄生漆树科植物盐肤木、青麸杨或红麸杨等树上形成的虫瘿,其主要成分为五倍子鞣质,能够凝固微生物体内的原生质及多种酶,对多种细菌、真菌、酵母菌都有明显的抑制作用。

Chinese Cinnamaldehyde which also named Cinnamaldehyde alias, is the main component of volatile oil which obtained by steam distillation from dry skin and cinnamon bark of lauraceae plants . It is researched as a root canal sterilization drug in recent years, it can seriously undermine the bacterial cell surface structure, and thus has a wider antibacterial spectrum and strong antibacterial activity; gallnut hundred, also known as worms, it is a kind of gall that be formatted by Schlechtendalia species of insects including Schlechtendalia and times aphid eggs in their parasitic plants Anacardiaceae Rhus chinensis, Green bran Yang or red bran Yang, the main ingredient for gallnut tannin, can solidification microbial protoplasts and a variety of body enzymes, a wide range of bacteria, fungi, yeasts are inhibited.

中药桂皮醛别名肉桂醛,是樟科植物肉桂的干皮及树皮经水蒸气蒸馏得到的挥发油中的主要成分,是近年来研究较多的根管消毒药物,它能够严重破坏细菌细胞表面结构,从而具有较广的抗菌谱和较强的抗菌活性;五倍子又名百虫,是倍蚜种昆虫角倍蚜或倍蛋蚜在其寄生漆树科植物盐肤木、青麸杨或红麸杨等树上形成的虫瘿,其主要成分为五倍子鞣质,能够凝固微生物体内的原生质及多种酶,对多种细菌、真菌、酵母菌都有明显的抑制作用。

Interestingly at l2h Cinnamylaldehyde could increase HUVEC adherence to THP-1.(5) At 4h and l2h Muscone decreased PMN-HUVEC adhesion, as well as inhibited ICAM-1, VCAM-1 and CD44 expression on TNF-primed HUVEC. But it markedly increased HUVEC adherence to THP-1 at 12h.

结果提示:黄芪多糖、川芎嗪、桂皮醛和麝香酮可以抑制PMN与HUVEC粘附并抑制HUVEC表面粘附分子的表达,桂皮醛和麝香酮能明显促进THP-1与HUVEC粘附。

It was found that the content of cinnamaldehyde was decreased with the rise of temperature and ethanol contents.

结果表明:桂皮醛含量随乙醇体积分数、温度的升高而降低,随振荡时间延长而增加,但4h后桂皮醛含量基本不再发生变化。

The effects of solvent, temperature, and shaking-time on the content of cinnamaldehyde in the microcapsules were also studied.

桂皮醛为客体,β-环糊精为主体,研究了乙醇体积分数、温度、振荡时间对悬浮液法制备微胶囊中桂皮醛含量的影响。

The purpose of this study was to develop the optimal microemulsion formulation using cinnamon oil as model drug. Cinnamaldehyde is the highest content in cinnamon oil and selected as the indicator for analysis by gas chromatography.

本研究以精油中之桂皮油为研究主题,由於其为一混合物组成复杂,为能正确进行定量分析,便以在桂皮油中含量最高之桂皮醛作为分析指标成分,利用气相层析仪建立其定量分析方法。

The cinnamaldehyde level in the blood wasn't detected, so the concentration of hippuric acid was substituted by GC method in the urine. In addition, the skin irritation was measured by colorimeter, and the result was exhibited that the formulations of cinnamon oil microemulsion didn't cause the obvious skin irritation.

慊/cm2/hr。体内经皮实验结果显示,经由动物皮肤给予时,体内及皮内可测得之桂皮醛浓度并不多,推测处方中部份桂皮油可能会经体内快速代谢并经肾脏排除,此外在该微乳剂处方对皮肤之刺激性评估,由色差仪所测定之结果显示,经制备所得之桂皮油微乳剂处方对皮肤不具有明显刺激性。

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