核酸酶

The main products as follows: aprotinin, chymotrypsin, trypsin, deoxyribonuclease, kallikrein enzymes and enzyme products.

主要产品为：抑肽酶、糜蛋白酶、胰蛋白酶、脱氧核糖核酸酶、激肽释放酶等酶类制品。

However, the oligonucleotide is easy to be discomposed by nuclease and difficult to reach the target.

肽核酸既不是典型的核酸也不是典型的蛋白，它能抵抗核酸酶和蛋白酶的分解。

Based on the sources, molecular weights, pI, characters of chromatography and electrophoresis, substrate specificities of these enzymes, it can be concluded that many kinds of nuclease-like enzymes have been found in the tissues of Lumbricus Bimastus.

根据这些酶的来源、分子量、等电点、层析和电泳等行为以及底物特异性等，初步证明，我们新近发现了双胸蚓组织中存在着多种核酸酶样酶。

DNA methyltransferases, homing endonucleases, nicking enzymes, specificity subunits and control proteins are also included.

还包括DNA甲基转移酶、趋巢性内切核酸酶、切割酶、专一亚单位和控制蛋白质。

The pathogen of gas gangrene mainly exist and live in local place, and seldom enter blood system to cause blood poisoning, but than can form lots of toxins, this toxins can harm blood system, kidney system, and also the tissue can putrescence and the wound will enlarge step by step, all tissue putrescence and toxin can make these bacteria easier to live and reproduce, all these situation if not being control in time will lead a serious situation that multiple organs dysfunction and then died

气性坏疽的病原菌主要在伤口内生长繁殖很少侵入血液循环引起败血症。产气夹膜杆菌产生α毒素、胶原酶透明质酸酶、溶纤维酶和脱氧核糖核酸酶等，红细胞破坏引起溶血血红蛋白尿、尿少、肾组织坏死水肿、液化，肌肉大片坏死使病变迅速扩散、恶化。糖类分解产生大量气体使组织膨胀；蛋白质的分解和明胶的液化，产生硫化氢，使伤口发生恶臭由于局部缺血，血浆渗出，及各种毒素的作用伤口内的组织和肌肉，进一步坏死和腐化，更利于细菌的繁殖使病变更为恶化。

It is a very basic, single-chain protein with molecular weight about 14 kD. It shares 33% sequence identity with bovine pancreatic RNaseA and has structurally equivalent counterparts for the two histidines and one lysine that comprise the catalytic residues for ribonucleolytic activity.

它是由123个氨基酸组成的分子量约为14kD的单链碱性蛋白质，与牛胰核糖核酸酶有33％的同源性，两个组氨酸和一个赖氨酸残基组成了血管生成素核糖核酸酶活性中心。

By using lysozyme, RNase A and protein disulfide isomerase as model proteins, we present a hypothesis that protein cross-linking can be accomplished in three concerted steps:(1) a change in protein conformation;(2) formation of interchain disulfide bonds; and (3) formation of interchain isopeptide cross-links.

我们以溶菌酶、核糖核酸酶A和蛋白质二硫键异构酶为模型对异肽键进行了体外详细的研究，提出了解释异肽键形成机理的假说：1蛋白质发生构象变化包括二级结构的改变；2蛋白质形成分子间二硫键：3二硫键的形成帮助蛋白质形成了分子间异肽键。

In addition,ribozymes can also be artificially designed. For all these reasons,the discovery of the ribozymes provide more specific methods of gene therapy on the human cancer.

研究表明，核酶具有较单链的反义核酸更为稳定和简单的空间结构，不易受到核酸酶的破坏，因结构简单，可以人工设计。

The beauty of zinc-finger nucleases lies in their simplicity. Where other methods are long, arduous and often messy, it is relatively easy to switch off genes using this method.

锌指核酸酶的美妙之处就在于其简单性，比起其它费时、费力又麻烦的方法来，利用锌指核酸酶的方法能够相对容易地沉默基因。

Because artificial nucleases can cleave nucleic acids at specific sequnce or site, it can be used as very important tools in molecular biology, can be applied to gene therapy, purity of proteins, anti-sense PCR technique, DNA footprinting and chemical probe, and so on.

由于人工核酸酶可在核酸底物的特定部位将其断裂，所以它可以作为重要的分子生物学工具，可应用于疾病的基因治疗，蛋白质分离纯化中去除核酸，还可用于反义PCR技术、DNA足迹技术、化学探针等。

Breath, muscle contraction of the buttocks; arch body, as far as possible to hold his head, right leg straight towards the ceiling (peg-leg knee in order to avoid muscle tension).

呼气，收缩臀部肌肉；拱起身体，尽量抬起头来，右腿伸直朝向天花板（膝微屈，以避免肌肉紧张）。

The cost of moving grain food products was unchanged from May, but year over year are up 8%.

粮食产品的运输费用与5月份相比没有变化，但却比去年同期高8％。