核质酵素

These two series of probes differ in their mechanism of action. The first series exploits the concept of suicide substrate. When the probe is hydrolyzed by the target sulfatase, it will release an intermediate that undergoes elimination to form a reactive quinone methide which in turn reacts with nearby nucleophiles. The second series belongs to an electrophilic reagent which utilizes a cyclic sulfamate moiety serving both as the recognition unit and the trapping device.

这二系列标示分子的主要差异在於其标示机制，第一系列是源自於自杀性受质的概念，利用水解后的中间体会生成高反应性的quinone methide，来达到标示的效果；第二系列则是属於亲核性试剂型，采用环状胺基磺酸衍生物做为辨识端及捕捉机制，预期在其进入酵素的受质结合区后能与酵素催化中心形成共价键结。

Breath, muscle contraction of the buttocks; arch body, as far as possible to hold his head, right leg straight towards the ceiling (peg-leg knee in order to avoid muscle tension).

呼气，收缩臀部肌肉；拱起身体，尽量抬起头来，右腿伸直朝向天花板（膝微屈，以避免肌肉紧张）。

The cost of moving grain food products was unchanged from May, but year over year are up 8%.

粮食产品的运输费用与5月份相比没有变化，但却比去年同期高8％。