核苷酸

By phylogenetic analysis of 5'NC, E and NS5B region, HCV can be divided into 6 major genotypes and each genotype has several subtypes.

根据HCV基因组5'NCR、C、NS5B区核苷酸序列的同源性，HCV可分为6个主要基因型，每个型又可分为若干亚型。

Recently, the cDNA encoding PTA1 has been cloned from activated Jurkat cells by Sherrington and show it to be a novel member of the immunoglobulin superfamity with the unusual structure of two V domains only. This result provided a fundamental base for further study on PTA1 functions and its ligand identification.

从核苷酸推导的氨基酸序列表明PTA1由334个氨基酸组成，先导序列18个氨基酸，成熟PTA1分子为316氨基酸，胞膜外区232个氨基酸有两个Ig样结构域，属于免疫球蛋白超家族成员，胞浆区59个氨基酸中，含有3个酪氨酸，6个丝氨酸和6个苏氨酸，有PKC和PTK作用的基序，这些特征都与PTA1分子的功能密切相关，因此PTA1 cDNA克隆成功为进一步深入研究PTA1分子的作用机理奠定了坚实的基础。

Sendai virus ; genome ; nucleotide sequence analysis

仙台病毒；基因组；核苷酸序列分析

Objective: The aim of this study was to investigate the effects of ginsenoside Rg3 and ginsenoside Rg3 combined with cisplatinon the growth of nude mice cervical cancer, and to explore the possible mechanism of ginsenoside Rg3 and ginsenoside Rg3 combined with cisplatinin cells and molecules levels. The growth of human cervical cancer Hela cell, apoptosis of tumor cells , expression of CD31and PeNt were observed with optic microscope, radio-immunity immunological histo chemistry, terminal deoxynucleotidy transferase-mediated dUTP nick end labeling, and immunohistochemical staining. The purpose of this study is to provide a new way of medication to eure cervical cancer in clinic.

目的：本实验通过建立子宫颈癌裸鼠病理模型后，以此为研究对象，运用光镜、免疫组化及末端脱氧核苷酸转移酶介导的dUTP缺口末端标记技术，观察人参皂甙Rg3[20—Ginsenoside Rg3]和顺铂单独及二者联合应用对人宫颈癌Hela细胞裸鼠移植瘤生长的影响，重点研究肿瘤的生长、肿瘤细胞的凋亡及PCNA、CD31的表达情况，以期从细胞及分子水平揭示人参皂甙Rg3和顺铂单独及二者联合应用对人宫颈癌Hela细胞的作用机制，为临床上药物治疗与预防宫颈癌寻找更加完善的途径。

Results A Tru9 I restriction fragment length polymorphism in the 5′ flanking region of the FⅨ gene was first identified in Guangxi.

结果 首次在广西人群中发现FⅨ基因5′侧翼698位核苷酸存在Tru9 I多态性，该多态性由83 bp/58 bp+25 bp组成，二者的基因频率在受检的180个FⅨ基因中，分别为0.622和0.378，女性杂合子频率为0.473。

The sensibility and specificity of the method were evaluated with the amplification and by sequencing randomized Rh-negative and Rh- positive controls.

序列特异性引物方法扩增RHD 基因特异的外显子及其侧翼序列，PCR产物直接序列分析测定核苷酸的变异。

Results Both Src and Fyn antisense ODNs showed a protective role against neuronal cell death induced by cerebral ischemia/reperfusion. Furthermore, administration of Src antisense ODNs had more protective effect on the neuronal death than Fyn antisense ODNs.

结果 Src、Fyn反义寡核苷酸对脑缺血再灌注后海马CA1神经细胞均有明显保护作用，以Src AS ODNs保护作用更明显，与缺血组比较约有50%细胞存活(P.05)。

Antisense oligonucleotide of Gqα has no effect on Gs and Gi mRNA expression.

Gqα反义寡核苷酸对Gs和Gi的mRNA表达没有影响。

Breath, muscle contraction of the buttocks; arch body, as far as possible to hold his head, right leg straight towards the ceiling (peg-leg knee in order to avoid muscle tension).

呼气，收缩臀部肌肉；拱起身体，尽量抬起头来，右腿伸直朝向天花板（膝微屈，以避免肌肉紧张）。

The cost of moving grain food products was unchanged from May, but year over year are up 8%.

粮食产品的运输费用与5月份相比没有变化，但却比去年同期高8％。