核苷酸

This advance represents an improvement of two orders of magnitude over traditional Sanger sequencers in terms of the number of nucleotides per unit time, allowing even small groups of researchers to obtain huge volumes of genomic data over fairly short period.

按照在单位时间产生的核苷酸的数目来讲，这个进步比传统的Sanger测序仪提高了两个数量级，允许小的研究组在相当少的时间内，获得大量的基因组信息。

The advent of high-throughput DNA sequencers has increased the pace of collecting enormous amounts of genomic information, yielding billions of nucleotides on a weekly basis.

高通量DNA测序仪的出现提高了收集大量基因组信息的速度，每周产生十亿的核苷酸。

With same concentration and same bases, the blocking efficiency of PNAs sames better than ODN's.

相同碱基组成、相同作用浓度下肽核酸的反义封闭效果明显优于寡核苷酸。

They are, says Joshua Mendell, M.D., Ph.D., an assistant professor in the McKusick-Nathans Institute of Genetic Medicine at Hopkins, like "molecular rheostats that fine-tune how much protein is being made from each gene."

有关这个看似&离经叛道&核苷酸序列以及它们在细胞中神秘移动的秘密都写在了1月5日发表的《Science》杂志上。

Nucleotide Sequence Analyses of Provirus Gene of Human T-Lymphotropic Virus Type Ⅰ from an Inhabitant of Shaotou Region in Southeast China

中国汕头地区一株人类嗜T细胞病毒Ⅰ型前病毒的核苷酸序列分析

In a summary,in this study,the entire provirus genomes of EIAV L and DLA-EIAVprovirus were cloned and sequenced.Speculation about the function and structure of EIAVgenome was drawn upon the comparison of EIAV L,DA-EIAV,DLA-EIAV and other alienEIAV strains.

总之，本研究首次获得了我国DLA-EIAV和L株前病毒全基因克隆，确定了DLA-EIAV和L株前病毒基因组核苷酸全序列，并对EIAV L株、DA-EIAV、DLA-EIAV及国外相关的EIAV毒株进行了比较分析。

To elucidate the molecular basis of the attenuation ofDLA-EIAV in virulence thus provide theory foundation for designing HIV vaccine, thewhole genomes of DLA-EIAV and EJAV L provirus were cloned and sequenced. Aninfectious molecular clone derived from DLA-ELAV was constructed and characterized.Three DLA-EIAV/ L chimeric viruses were constructed. Promoting efficacy of the longterminal repeat of the DLA-EIAV was charactenzed.

为了揭示我国马传贫弱毒疫苗毒力致弱及免疫保护的分子机制，为人免疫缺陷病毒及其它慢病毒的免疫预防提供借鉴，我们对马传贫驴白细胞弱毒及其亲本马强毒EIAV L株前病毒进行了全基因克隆和序列测定，比较分析了二者的前病毒基因组核苷酸序列，在此基础上构建了EIAV驴白细胞弱毒株的感染性分子克隆和三株含有EIAV强/弱毒嵌合病毒基因组的重组质粒，并对EIAV弱毒株长末端重复序列的启动子活性进行了初步研究。

To elucidate the molecular basis of the attenuation ofDLA-EIAV in virulence thus provide theory foundation for designing HIV vaccine,thewhole genomes of DLA-EIAV and EIAV L provirus were cloned and sequenced.Aninfectious molecular clone derived from DLA-EIAV was constructed and characterized.Three DLA-EIAV/L chimeric viruses were constructed.Promoting efficacy of the longterminal repeatof the DLA-EIAV was characterized.

为了揭示我国马传贫弱毒疫苗毒力致弱及免疫保护的分子机制，为人免疫缺陷病毒及其它慢病毒的免疫预防提供借鉴，我们对马传贫驴白细胞弱毒及其亲本马强毒EIAV L株前病毒进行了全基因克隆和序列测定，比较分析了二者的前病毒基因组核苷酸序列，在此基础上构建了EIAV驴白细胞弱毒株的感染性分子克隆和三株含有EIAV强/弱毒嵌合病毒基因组的重组质粒，并对EIAV弱毒株长末端重复序列的启动子活性进行了初步研究。

Results The proband had a del-aa at nucleotide 72045 in exon 5, both of her parents and sister were correspondingly heterozygotes at the same nucleotide.

结果 先证者第72045位缺失两个核苷酸A，位于外显子5；先证者的父母及先证者的姐姐分别在DNA水平相同位点呈杂合缺失。

In accordance with oligonucleotides immobilization, the presences of new chemical structures at different stages were also identified in this study.

对於寡核苷酸引子固定在SAMs上，各阶段新的化学结构变化也给予验证。

Breath, muscle contraction of the buttocks; arch body, as far as possible to hold his head, right leg straight towards the ceiling (peg-leg knee in order to avoid muscle tension).

呼气，收缩臀部肌肉；拱起身体，尽量抬起头来，右腿伸直朝向天花板（膝微屈，以避免肌肉紧张）。

The cost of moving grain food products was unchanged from May, but year over year are up 8%.

粮食产品的运输费用与5月份相比没有变化，但却比去年同期高8％。