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核苷酸

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The prestent invention discloses the cDNA sequnce of a new human reduced NADH: ubiquinone oxidoreductase 14 KDa subunit (NADH-CoQ14KDa subunit). The protein coded with the sequence is the homolog of ox's NADH-CoQB14.5b subunit.

本发明提供了一种新的人还原型烟酰胺腺嘌呤二核苷酸-辅酶Q氧化还原酶14千道尔顿亚基(NADH:ubiquinone oxidoreductase 14 kDa subunit,简称为&NADH-CoQ 14 kDa亚基&的cDNA序列,该序列编码的蛋白是牛NADH-CoQB14.5b亚基的同系物。

Those little tykes, just 24 nucleotides long, are somehow responsible for methylation of DNA sequences that match the sequence of the siRNAs, but not without a lot of help from their friends.

这些siRNAs,仅仅具有24个核苷酸的长度,负责甲基化与它自身序列配对的DNA序列,这种过程是在其他&朋友&的帮助下进行的。

Those little tykes, just 24 nucleotides long, are somehow responsible for methylation of DNA sequences that match the sequence of the siRNA s, but not without a lot of help from their friends.

这些 siRNA s,仅仅具有24个核苷酸的长度,负责甲基化与它自身序列配对的DNA序列,这种过程是在其他&朋友&的帮助下进行的。

In the first part of this dissertation, positional distributions of overlapping trimers are focused. Artificial neural network , genetic algorithms and Markov model have been applied to DNA sequence motif finding problems by developing neural network model and Markov model for recogniting these DNA sequence motif.

本文第一部分采用人工神经网络、遗传算法和马尔科夫模型这三种模式识别算法,对启动子、外显子和内含子序列中核苷酸联体的分布特性作深入探讨,发现其中的某些普遍规律,并建立识别这些DNA序列基元特征模式的神经网络模型或马尔科夫模型,已成功用于未知序列的预测。

AIM: To investigate the effect of exogenous nucleotides on the repair of damaged DNA in mouse thymocytes in vitro.

目的:探讨外源核苷酸对受损小鼠胸腺细胞DNA修复的影响。

To investigate the methods to effectively and simply assess the CAG repeat size of HD gene which was necessary for gene diagnosis of Huntington disease, the sequence including polymorphic CAG repeat of HD gene was amplified by PCR with TaKaRa LA Taq DNA polymerase and GC buffer. PCR products were analyzed on polyacrylamide gel to distinguish normal alleles from HD alleles. The DNA fragments of affected alleles were recovered from polyacrylamide gel as templets for secondary PCR. The secondary PCR products were cloned into T vector for sequencing analysis to determine CAG repeat size. A total of 20 normal individuals and 3 members from a HD pedigree were included in this study.

为了简单高效检测HD基因开放阅读框5'端n三核苷酸重复序列,建立快速准确的亨廷顿病(Huntington disease, HD)基因诊断方法,应用TaKaRa LA Taq DNA聚合酶配合GC buffer扩增HD基因包含n重复序列的目的片段,非变性聚丙烯酰胺凝胶电泳检测后回收n拷贝数异常增多的目的片段,再次PCR扩增后将产物连接至T载体,进行DNA测序确定CAG的拷贝数。

At last, we determinated those templates by means of dideoxy method, and further analyzed the sequence information with bioinformatics softs, such as Bioedit, Mega, etc..

最后将获取的测序模板使用双脱氧法测定核苷酸序列。

The most common version of this,(shown be-low) uses a one-letter code for each nucleotide and a three-letter code for each amino acid.

最常见的版本,,使用一个字母代码为每个核苷酸和三个字母代码为每个氨基酸。

The most common version of this,(shown be-low) uses a one-letter code for each nucleotide and a three-letter code for each amino acid.

此的最共同的版本,为每核苷酸使用一个一信件代码和一个三信件代码为每氨基酸。

They analyzed 500,000 one-letter ariations, or single nucleotide polymorphisms, in their DNA to look for commonalities. They then confirmed possible culprits in two separate studies of Germans and French-Canadians.

为了找出共同特征,他们分析了他们DNA中500,000个单基因突变或者单核苷酸多态性,最终在关于德国人和法籍加拿大人的两个独立的研究中确定了可能的致病突变。

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然而,正如其名字所指出的那样,CD盘不能写,也不能用任何方式改变其内容。

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