核小体

These variants change the conformation and stability of nucleosome to facilitate transcriptional activation or deactivation, DNA repairing, heterochromatin formation, and others.

这些变体通过改变核小体的空间构象和稳定性，决定基因转录的激活或沉默，DNA的修复，染色体的异染色化等。

An attractive hypothesis has been a semiconservative mechanism in which parental histones are combined with newly synthesized histones within the same core nucleosome.

一个有吸引力的假说是半保留的机制，在这一机制中，亲本的组蛋白和新合成的组蛋白共存于同一核小体核心中。

Core particles ) Particles resulting from micrococcal nuclease digestion of nucleosomes, consisting of 140-bp DNA and the histone octamer of a nucleosome.

在真核生物中，双螺旋的 DNA 分子围绕一蛋白质八聚体进行盘绕，从而形成特殊的串珠状结构，称为核小体。

In the study, a set of near isogenic lines of CMS-S, S-Mo17Rf3Rf3 and S-Mo17rf3rf3, were adopted, and TdT-mediated dUTP nick-end labeling, in situ immunolocalization of cytochrome c and DNA ladder assay were employed to study the programmed cell death process on cytology and DNA level. The microscope observation evidenced that tapetal cells of fertile anthers kept intact until microspores, and then were disintegrated on later developmental stage.

S型细胞质雄性不育系的一对近等基因系S-Mo17Rf3Rf3 和S-Mo17rf3rf3为材料，采用TdT介导的dUTP DNA末端标记、细胞色素C免疫原位杂交和DNA寡聚核小体片段电泳等方法，分别在细胞学水平和DNA水平上研究了玉米CMS-S小孢子败育的细胞程序性死亡过程。

Results: Compared with that treated with anti-thyroid drugs alone, after the combined therapy, the size of thyroid decreased significantly, P＜0.01. Typical apoptosis appearance, such as vacuolated cell, marginal nuclei, chromatin condensation and nuclear fragmentation, could be seen under light microscopy. The apoptotic rate before and after adding Chinese herbs was (2.11±1.78)%and (18.66±20.01)%respectively (P＜0.01). TUNEL positive cells were detectable for up to 2-20 weeks after Chinese herbal treatment.

结果：与单纯抗甲状腺药物治疗比较，患者经抗甲状腺药物与中药联合应用治疗2-10周后，甲状腺组织明显缩小(P＜0.01)；光镜下可见细胞发泡、核着边、核固缩、核小体、核分裂等凋亡细胞的典型形态；加中药治疗前后甲状腺细胞凋亡比率分别为(2.11±1.78)%和(18.66±20.01)%(P＜0.01)；末端标记呈阳性。

In eukaryotes, DNA left-handed chirality by the way, wrapped around histone octamer around, the formation of a stable nucleosome structure.

在真核生物中，DNA按左手手征性的方式，缠绕在组蛋白八聚体的周围，形成稳定的核小体结构。

In eukaryotic cells, the fundamental unit of chromatin is nucleosome, which is composed of a histone octamer with two copies of H2A, H2B, H3 and H4 and 146 base pairs of DNA.

真核细胞中，核小体是染色质的基本单位，它由两个拷贝H2A、H2B、H3和H4所组成的核心组蛋白八聚体，及缠绕于其上的146bp DNA构成。

Which combinations of histones form " histone-fold " dimers with each other in the nucleosome?

在核小体中，每个组蛋白二聚体分别由哪几种组蛋白组成？

The general features of nucleosome structure appear to be similar in all eukaryotes.

核小体结构的一般特性似乎在所有的真核生物中都很相似。

High mobility group protein; enhanceosome ; nucleosome ; regulation of gene expression

高迁移率族蛋白；增强体；核小体；基因表达调控

I can not make it blossom and suits me

我不能让树为我开花

When temperatures are above approximately 80 °C discolouration of the raceways or rolling elements is a frequent feature.

当温度高于 80 °C 左右时，滚道或滚动元件褪色是很常见的特征。