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In this thesis the process of constructing the non-perturbative Hamiltonian theory is de-scribed and is applied to estimate the vacuum condensate. It contains the following contents:At the very beginning, by using the path integral method and eliminating the gluon freedom, aGCM action 〓 of current quarks including lower order current-current coupling was derivedfrom the QCD Lagrangian and the effective Hamiltonian operator that could hardly be doneby the normal methods was derived. After doing this, the broken vacuum is introduced whichincludes quark-antiquark condensate through the generalized Bogoliubov-Valatin transformation,the effective Hamiltonian of constituent quark was derived. The detailed formulas containingthe spatial current-current coupling term for the effective Hamiltonian and gap equations wasworked out by parameterizing the correlation kernel as a quadratic potential. And then, the gapequation was solved and the quark-antiquark condensate of vacuum was studied both in the casesof instantaneous interaction and retarded interaction. In the end, the effective Hamiltionian withtwo-body quark-quark interaction was derived with one-body approximation, and with the helpof the functional integral method the coupling non-linear dynamic equations for systems withnuclear matter was derived. Finally, these equations were solved by selfconsistent method andthe effect of nuclear matter on vacuum condensate was studied. The spatial current-current coupling term is too difficult to handle, hence the correlationkernel is assumed to be not important and usually omitted in the pure vacuum condensate, andthe instantaneous interaction generally is adopted. Retaining the spatial current-current termand partial retardation effect, the quark pairs condensate in pure vacuum was studied, and theeffect of quark mass was also studied. At present, little study is focused in the case with nuclearmatter and spatial current-current term also omitted. Under the approximation with partialspatial current-current term, the effect of nuclear matter on vacuum condensate was studied.

本论文描述了量子色动力学整体色对称模型哈密顿量方法的构建过程,得到了反映正反夸克对凝聚真空结构的关于组分夸克的有效哈密顿量算符,它隐含了胶子作用,并且准确至流-流耦合项;接着,通过参数化哈密顿量中的夸克作用关联核,导出平方禁闭势参数化选择的哈密顿量的具体公式和能隙方程;随后,应用公式,编程求解,考察了瞬时作用下和部分延迟作用下真空的正反夸克对凝聚,在计算中保留了空间流-流耦合作用;之后,导出瞬时势和延迟势下包含二体作用项的哈密顿量公式,并采用单体化近似,通过泛函变分方法得到核物质存在时耦合的非线性动力学方程;在保留部分空间双流耦合作用的近似下,求解核物质的动力学方程,考察核物质密度对真空凝聚的影响,以往考察真空凝聚,对关联核的选用,由于空间流-流耦合项不易处理,也认为作用不大,常忽略该项,并且常采用瞬时作用;本文保留空间双流项和部分延迟作用,考察了真空情形的夸克对凝聚,还考察了夸克质量对纯真空凝聚的影响,以往对核物质存在情形的真空凝聚考察很少,也都忽略空间流-流项,本文在考虑部分空间流-流项近似下,考察了核物质存在对真空凝聚的影响。

The bonding energy of the mixed covalent/metallic Ti-Al bond for the Ti-terminated Al/TiB_2 interface is larger than that of the polar covalent Al-B bond with partial ionic-like feature for the B-terminated interface. Metallic bond between Al atoms forms across the Al/AlB_2 interface, which results in weaker interfacial adhesion than that for the Al/TiB_2 interface. The interfacial energy for Al/TiB_2 depends on the interfacial chemical potential.

Al熔体中仅存在TiB_2粒子,而无多余溶质Ti时,α-Al在TiB_2粒子上异质形核产生的Al/TiB_2界面能大于α-Al从Al熔体中直接形核时的液-固界面能,不满足TiB_2粒子充当α-Al有效异质形核核心的能量条件,这从理论上解释了Al熔体内仅存在TiB_2粒子时无晶粒细化效果的实验现象。

E. , ACTH antagonizes the analgesia mediated byμand δ opioid receptors, but notκreceptor;(2) The antagonizing effect of ACTH on opioid analgesia is proposed to be mediated by ACTH receptors, although the latter has not been characterized;(3) A contradictory interaction on intracellular cAMP content may constitute one of the postreceptor mechanisms underlying ACTH antagonism of opioid analgesia;(4) Another proposed mechanism of the anti-opioid effect of ACTH is that ACTH can modulate opioid-induced suppression of calcium influx;(5) ACTH has been shown to induce Fos protein expression in selected areas of the rat brain including the nuclei involved in pain regulation as well as the ependyma of the third ventricle and the aqueduct.

根据以上实验结果,本论文首次提出以下论点:(1)ACTH在脊髓水平对抗阿片镇痛具有受体选择性,即ACTH可对抗μ受体和δ受体介导的镇痛,不对抗κ受体所介导的镇痛;(2)由于ACTH与阿片μ受体的肽类配体的结合位点仅有很低的亲和力,与μ受体的非肽类配体的结合位点以及δ受体无亲和力,推测ACTH是通过中枢内的ACTH受体介导发挥抗阿片效应的;(3)ACTH抗阿片作用的受体后作用机制之一是在cAMP信使通路水平与阿片发生相互作用;(4)ACTH抗阿片作用的另一受体后机制是在〓水平影响阿片的效应;(5)通过Fos蛋白的诱导揭示:ACTH可以作用于脑内多个核团,其中包括许多与痛觉调制有关的核团,推测ACTH可能通过激活这些核团的神经元而发挥其中枢效应。

Results Many neuronal cell bodies and fibers with dense mGluR7-like immunoreactivity were intensely distributed in the island of Calleja,hippocampus,dentate gyrus,medial habenular nucleus,olivary pretectal nucleus,zonal layer of the superior colliculus,superficial layers of the caudal spinal trigeminal nucleus,paratrigeminal nucleus,raphe magnus nucleus,raphe nucleus pallidus,locus coeruleus,superficial layers and lateral spinal nucleus of the spinal cord.

结果 mGluR7阳性浓染的神经元胞体和纤维主要密集分布于Calleja岛、海马、齿状回、内侧缰核、橄榄顶盖前核、上丘带状层、三叉神经尾侧亚核浅层、三叉旁核、中缝大核、中缝苍白核、蓝斑、脊髓背角浅层和外侧脊核。

The results showed that in addition to ACTH_(1-39)-immunoreactive neurons found in the infundibular nucleus of the hypothalamus which were identical with the previous reports, negafivt ACTH_(1-39)immunoreactive neurons were also found in paraventricular and supraoptic nuclei.

结果表明除了在下丘脑漏斗核观察到的ACTH_(1-39)免疫反应神经元胞体和以往文献报道一致外,在室旁核、视上核内也有ACTH_(1-39)免疫反应细胞体。

Yu C G%Ma M%Ding T%Hetrick F,Hsu H T Biochemical characterization and time course analysis of Lymantria dispar nuclear polyhedrosis virus with monoclonal antibodies Canadian Journal of Microbiology , 1992,null

王根 棉铃虫核型多角体病毒多角体蛋白基因的克隆和核苷酸序列分析病毒学报, 1997,(1)吴柏春 1990中国棉铃虫核型多角体病毒VH A273毒株多角体蛋白某些理化特性的研究病毒学杂志, null,null

It introduced the classical theory of bubble nucleation during the process of foam plastics , and presented the calculation formulas about the radius of critical nucleation , required Gibbs free energy and nucleation rate of some kinds of nucleation. It reviewed the development of classical theory of bubble nucleation , including the influence of free volume and oversaturation on bubble nucleation , and pointed out the existing deficiencies in explanation of classical theory of bubble nucleation to bubble nucleation of dynamic polymer melt.

介绍了泡沫塑料加工过程中气泡成核的经典理论,给出了几种成核方式的临界成核半径、所需克服的吉布斯自由能及成核速率的计算公式;评述了经典成核理论的发展,包括自由体积和气体过饱和度对气泡成核的影响,并分析指出了经典成核理论对动态聚合物熔体气泡成核解释存在的不足。

Finally, the cytotoxic and antibacterial activities of the oxamido-bridged binuclear complexes were studied in vitro.. This dissertation consists of three sections as follows:1. The crystal structure of a oxamide dinitrate,(1) [H_4dmaeoxd](NO_3)_2 H_2dmaeoxd = N,N\'-bis[2-ethyloxamide, has been obtained. The diversity of complexes with different structures is carried out by successful synthetic strategy of controlling species of metal ions, counter anions, pH values and solvents in the course of synthesis. Four dinuclear complexes bridged by trans-dmaeoxd2-: [Cu_2_2](ClO_4)_2 (2), [Cu_2_2](ClO_4)_2 (3),、[Cu_2(Me_2phen)_2](ClO_4)_2 (4), [Cu_2_2(H_2O)_2] (5); Four dinuclear complexes bridged by cis-dmaeoxd2-: [NiNi_2](ClO_4)_2 (6), [CuNi_2](ClO_4)_2·2CH_3OH (7), [CuZn_2]-(ClO_4)_2·2H_2O (8), [Cu(H_2O)Ni_2](ClO_4)_2.0.5CH_3OH (9); three 1-D polynuclear complexes: [Cu_2]_n·nH_2O (10), [Cu_2(H_2O)_2-]_n·4nH_2O (11), [Cu_2(H_2O)]_n(NO_3)_n·2nH_2O (12); one 2-D polynuclear complex,[Cu_6_3(μ_3-OH)_2(H_2O)_2]_n(ClO_4)_(4n).2nH_2O (13); the others: [VO(H_2O)]·2H_2O (14), [Zn_2_4](ClO_4)_2·H_2O (15), [Cu_2]·2DCM (16) have been synthesized and characterized by X-ray single crystal diffraction, elemental analysis, IR spectra.

本论文主要包括以下三部分:一、合成得到了一个草酰胺配体硝酸盐的单晶结构,[H_4dmaeoxd](NO_3)_2 (1);通过调控金属离子的种类、端基配体、抗衡阴离子、溶剂、pH值等条件定向合成了四个反式草酰胺桥联双核铜配合物:[Cu_2_2](ClO_4)_2 (2)、[Cu_2_2](ClO_4)_2 (3)、、[Cu_2(Me_2phen)_2](ClO_4)_2 (4)、[Cu_2_2(H_2O)_2] (5);四个顺式草酰胺桥联同/异双核配合物:[NiNi_2](ClO_4)_2 (6)、[CuNi_2](ClO_4)_2·2CH_3OH (7)、[CuZn_2]-(ClO_4)_2·2H_2O (8)、[Cu(H_2O)Ni_2](ClO_4)_2.0.5CH_3OH (9);三个一维聚合物: [Cu_2]_n·nH_2O (10)、[Cu_2(H_2O)_2-]_n·4nH_2O (11)、[Cu_2(H_2O)]_n(NO_3)_n·2nH_2O (12);一个二维聚合物: [Cu_6_3(μ_3-OH)_2(H_2O)_2]_n(ClO_4)_(4n)。2nH_2O (13);单核钒配合物[VO(H_2O)]·2H_2O (14)、草酸根桥联双核锌配合物[Zn_2_4](ClO_4)_2·H_2O (15)、美洛西康铜配合物[Cu_2]·2DCM (16),利用元素分析、摩尔电导、红外光谱、电子光谱和单晶X-射线衍射对上述所得化合物进行了结构表征,探讨了结构影响因素,并研究了其超分子结构。

The formation of secondary phase in the non-equilibrium peritectic reaction was observed by precise transmission electron microscopy analysis. The microstructural evolution and phase selection regularities under different solidification velocities were constructed from the laser resolidification experiments. A new phenomenon involving two-phase coupled growth was firstly detected in the rapidly solidified Ti-Al peritectic alloy. The Ti-45Al-2Cr-2Nb alloy with fully lamellar structure ( a 2+ g ) was taken as an object to investigate the possible preparation of bulky metastable g phase materials based on both adjusting the competing nucleation relation and changing the growth kinetics condition.

首先通过过冷合金微观组织分析界定了各包晶合金熔体中各竞争相以初生相出现的过冷度区间;结合高温区的相图计算,从各相形核孕育时间角度揭示了过冷熔体中亚稳相与稳定相的竞争形核关系;通过精细微观组织分析,阐明了远离平衡时包晶反应中次生相的形成机理;在激光重凝快速凝固实验中建立了不同凝固速度下合金的组织与相形成规律,并对包晶合金中两相共生生长行为进行了深入分析;最后选取初生相为 a 的全层片 Ti-45Al-2Cr-2Nb 合金,从调整各相竞争形核关系和改变晶体生长动力学条件两个方面探索了块状亚稳 g 相材料的制备和控制。

In order to get the information of interaction between metal complex and DNA and select metal complexes which can cleave DNA effectively, twenty seven transition metal complexes containing O/N coordinate atoms have been synthesized in this thesis. We report the synthesis, crystal structure and properties of the complexes. One of the complexes is the first μ〓-oxalato tetranuclear Cu complex, in which there is ferromagnetic interaction between the copper atoms bridged by oxalate ions. Two trinuclear copper complexes containing partial cubane Cu〓O〓 cores have been synthesized and discussed the magnetic properties.

为了解金属配合物与DNA的相互作用及筛选能有效切割DNA的金属配合物,为无机药物合成及应用提供基础信息,本文利用十个含N、O原子的多齿配体设计合成了二十七个未见文献报道的过渡金属配合物,并解析了它们的晶体结构:其中包括首例μ〓-草酸根的四核铜配合物;合成了两个具有μ〓-OH〓三核缺角立方烷结构的Cu配合物;以HCBP衍生物为配体合成了七个过渡金属配合物;以SCN〓、N〓,C〓O〓等为桥联配体,以dmpyen为端基配体合成了十一个配合物。

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