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This study was designed to investigate the mechanisms of histone deacetylase inhibitors (sulfonamide anilide compound referred as the Compound') with antitumor activity against human bladder cancer cells. MATERIALS AND METHODS: Treated with different concentrations of the Compound and HCPT for different periods of time, human bladder cancer cell line BIU-87 growthwas measured by MTT assay.

材料与方法:以不同浓度的Compound和羟基喜树碱作用于体外培养的膀胱癌BIU-87细胞株;采用MTT法检测细胞生长抑制率;以流式细胞术测定不同浓度的Compound和HCPT作用前后膀胱癌细胞的调亡情况及细胞周期的变化;应用RT-PCR分析Compound和HCPT作用前后膀胱癌细胞中P21(上标 waf/cif1)mRNA表达的变化。

Sulfonamide anilide compound could inhibit human bladder cancer cell growth in vitro, most likely through induction of P21(superscript waf/cif1) mRNA expression and subsequent arrest of cell cycling at G1 phase.

Compound在体外能有效抑制对传统化疗耐药的人膀胱癌细胞生长,其抗肿瘤生长机制可能是通过上调P21(上标 waf/cif1)mRNA水平从而使细胞阻滞于G1期所致。

Effect of parameters including current density, temperature, acidity of anolyte and catholyte, concentration of nickel and NaCl in anolyte on preparation of nickel chloride solution is investigated.

研究了以镍基废合金板为原料,电流密度、温度、阳极液和阴极液的酸度、阳极液中NaCl和Ni(上标 2+)的浓度对电解制备氯化镍溶液的影响。

Report from our correspondent the mark on net inn is worn " taste really ", it is anonym card however actually.

本报讯网店上标着"真品",其实却是假名牌。

Concentration of Eu(superscript 3+) had different effects on anthraquinone production of roots.

Eu(上标 3+)浓度对不同类型大黄根的蒽醌产量有不同影响。

Using potassium antimonite technique, the development of the tapetum and Ca(superscript 2+) distribution in a genic-cytoplasmic male sterile line of Zhenshan 97A and its maintaining line Zhenshan 97B was studied.

利用焦锑酸钾沉淀法研究了野败不育系珍汕97A及其保持系珍汕97B绒毡层细胞的发育过程及其细胞中Ca(上标 2+)的分布变化。

There are few exceptions to this rule, and sometimes a crescendo is marked after an appoggiatura or dissonance; usually this dynamic is indicated in the text.

对这些规则有少数例外,有时在一个倚音或不谐和音后面标一个渐强记号;通常击键的力度也标明在乐谱上。

Hydroponics experiments was conducted to study the effect of Cd(superscript 2+) treatment (0, 0.01, 0.10, 0.50, 1.00 mmol/L respectively) on plant growth and some physiological and ecological identities of peanut Arachis hypogea L.

通过溶液培养,研究不同浓度镉Cd(上标 2+,0~1.00mmol/L对花生幼苗生长及生理生态特性的影响。

The flotation behavior of marmatite and arsenopyrite and the effects of Cu2 and organic depressant PALA on their floatability were studied.

通过浮选试验研究铁闪锌矿和毒砂在丁黄药作用下的浮选行为,以及Cu(上标 2+)和有机抑制剂PALA对它们可浮性的影响。

Those tribes are multiple and sometimes operate at cross purposes,and so figuring all that out is going to be much more of a challenge.

这些部族是多元化的,有时在管理上是有分歧的。所以*****有很多的挑战。所标出的不知如何翻译。

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However, as the name(read-only memory)implies, CD disks cannot be written onorchanged in any way.

然而,正如其名字所指出的那样,CD盘不能写,也不能用任何方式改变其内容。

Galvanizes steel pallet is mainly export which suits standard packing of European Union, the North America. galvanizes steel pallet is suitable to heavy rack. Pallet surface can design plate type, corrugated and the gap form, satisfies the different requirements.

镀锌钢托盘多用于出口,替代木托盘,免薰蒸,符合欧盟、北美各国对出口货物包装材料的法令要求;喷涂钢托盘适用于重载上货架之用,托盘表面根据需要制作成平板状、波纹状及间隔形式,满足不同的使用要求。

A single payment file can be uploaded from an ERP system to effect all pan-China RMB payments and overseas payments in all currencies.

付款指令文件可从您的 ERP 系统上传到我们的电子银行系统来只是国内及对海外各种币种付款。