染色质的

The types of histone methyltransferases, the relationship between methylation of Lysine 9 of H3 and the formation of heterochromatin, gene regulation in euchromatin, and that with DNA methylation, were mainly introduced.

主要阐述了组蛋白甲基转移酶的类型，组蛋白H3中第9位赖氨酸甲基化与异染色质的形成、常染色体中基因表达的调控，以及与DNA甲基化之间的关系，说明了组蛋白甲基化与组蛋白乙酰化、磷酸化的相互关系，指出组蛋白甲基化对维持细胞各种状态的平衡起到极其重要的作用。

Barrier is a kind of boundary elements, which blocks the spread of heterochromatin and insulates the neighboring active genes from repression effects.

障碍子就是边界元件的一种，它可以使活性基因的表达免受异染色质的的作用，防止基因沉默。

HIRA may function in regulating chromatin structure, nucleosome reassembly and cell cycle progression by the interactions of its different domains with different proteins.

HIRA可通过其不同的结构域与不同的蛋白质相互作用，来参与调节核小体的组装、染色质的结构及细胞周期的进程等。

Observ ed with transmission electron microscope and scanning electron microscope, t he apoptotic nuclei showed the typical morphological feathers of apoptosis: cond ensation and margination of chromatin, bubbling of nuclear membrane and apoptoti c bodies.

在透射电子显微镜和扫描电子显微镜下都观察到凋亡的细胞核呈现典型的凋亡形态学特征，例如染色质的凝集及趋边化，细胞核表面形成空泡化结构并有大量的凋亡小体结构出现。

All date above showed that SDG714 was involved in heterochromatin stability and the mechanism of histone methylation controlling DNA methylation was conserved in monocot.

表明SDG714影响异染色质的功能和染色体的稳定性，H3K9组蛋白的甲基化控制DNA的甲基化这一特性，在水稻中同样具有保守性。

The authors proposed that heterochromatin change in genome might play an important role in balancing the germplasms between maize and its distant relatve after cross and parthenocarpy.

这种变异不仅存在于表型不稳定的早代孤雌系中，而且还存在于表型稳定的高代系中，造成这种变异的原因可能是因为远缘种质的引入影响到遗传平衡进而引起染色体发生结构重排并引起染色质的变化，这种变化与玉米染色体组中非同源染色体间存在的同源片段和因此造成的减数分裂过程中非同源染色体配对有着直接的关系。

Spermiogenesis is a crucial process for germ cell formation, which ensures the efficient transmission of the paternal genome by the spermatozoa to the ooctyte at fertilization.

它包括染色质的压缩、顶体和鞭毛的形成以及去除多余的细胞质，是精子发生的一个重要环节，确保了成熟精子具有正确的形态和完整的功能。

Only Lamin A was observed to be able to be co-immunoprecipitated with 8B7 spectrin.Lamin A is a component in lamin and functions as a common anchoring site for many proteins.It plays important roles in maintaining normal morphology of nuclear envelope,presenting anchoring site for chromatin and reconstructing of nucleus.8B7 spectrin may function through interaction with Lamin A.

Lamin A是核纤层的组成成分，由LMNA基因编码，是核内许多蛋白分子的共同锚定物，在维持核膜的正常形态，提供染色质的锚定位点以及在核的重组过程中可能发挥重要作用。8B7血影蛋白可能经由Lamin A发挥功能。

In summary, the BRD7 gene acted as a candidate of tumor suppressor gene with NPC. The overexpression of BRD7 can partly reverse malignant phenotype of NPC cell line. The suppression effect of BRD7 on NPC tumorigenesis my be achieved by recognizing acetylated histone peptide through their motif-bromodomain, then modulating gene transcription by taking part in histone acetylating and chromosome remodeling, finally influencing signal-transduction pathways.

综上所述，BRD7基因作为一个重要的鼻咽癌抑瘤基因侯选者，在鼻咽癌细胞中的过表达后，可导致鼻咽癌细胞 HNE蛋白质表达谱发生改变，逆转其恶性表型，其作用机理可能是：BRD7基因通过其功能域彭聪硕士学位论文10Bromodomain与乙酚化的组蛋白特异性结合，参于染色体的乙酚化，染色质的组装，从而影响基因转录的调控，最终影响细胞内的信号传导通路并实现对细胞周期的调控，从而发挥抑制鼻咽癌细胞生长的作用。

DNA fluorescence dye Hoechest 33342 was used tomonitor the condensation of chromatin during germinal vesicle breakdown.

采用直接取核法获取卵母细胞生发泡，用同步化的HeLa细胞裂解液构建非细胞体系，将游离的生发泡培养在裂解液中，并加入荧光染料Hoechest 33342，观察染色质的变化情况。

With Death guitarist Schuldiner adopting vocal duties, the band made a major impact on the scene.

随着死亡的吉他手Schuldiner接受主唱的职务，乐队在现实中树立了重要的影响。

But he could still end up breakfasting on Swiss-government issue muesli because all six are accused of nicking around 45 million pounds they should have paid to FIFA.

不过他最后仍有可能沦为瑞士政府&议事餐桌&上的一道早餐，因为这所有六个人都被指控把本应支付给国际足联的大约4500万英镑骗了个精光。