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Autoradiography of aortas demonstrated uptake of the agent into macrophage-rich atheromata identified by Oil Red O staining of lipid deposits.

对主动脉的放射自显影证实该成像剂被通过脂质沉积物的油红O染色鉴定的富含巨噬细胞的动脉粥样硬化部位摄取。

During the PCD, condensation of nucleus, marginalization of chromatin, nuclear membrane shrinkage and destruction apparently occurred, and many vesicles appeared in the cytoplasm, which may be related to the degradation of cell substances.

正在凋亡的细胞核染色质固缩、趋边、核膜破裂或皱缩、细胞质囊泡化并将降解的物质运到周围细胞,从而保证了其它细胞正常发育以及生长的细胞对物质和能量的需求。

During the two critical periods—gametogenesis and preimplantation development, there are genome-wide epigenetic reprogramming in gametes and embryos, which plays important roles in the erasion or creation of imprinting, gene silencing and tissue-specific gene expression.

其中关键时期是配子形成期和胚胎植入前期,最主要内容是全基因组DNA"CpG岛"甲基化和染色质组蛋白乙酰化的有规律变化,结果是配子遗传印记的消除与重建、植入前胚胎大范围基因的静默和组织特异性基因表达的确定。

Nuclei are quite scattered and have only small, granular clumps of blue heterochromatin.

高倍镜显示平滑肌的胞浆嗜酸性,细胞核散在,核内有细小的颗粒状的蓝色的异染色质。

Recombination suppression in the sex-determining region and accumulation of deleterious mutations lead to degeneration of the Y chromosomes in many species with heteromorphic X/Y chromosomes.

这个问题一直困扰着科学家,在2008年最后一期的世界著名杂志《基因组研究》上,王秀娥和张文立博士发表了《番木瓜原始Y染色体的雄性特异区中DNA甲基化和异染色质化》的研究论文,初步揭示了性染色体的起源变化机制。

The apoptotic effects of LPS are detected by various skills such as fluorescence staining, TUNEL reaction, DNA agarose gel electrophoresis, electron microscopy and fluorescence activated cell sorting. Our results demonstrated that fish lymphocytes would be apoptotic under different LPS concentrations(above 10μg/ml) and different time(above 6h) inducing, which is characterized by condensation and margination of chromatin, the formation of apoptotic bodies.

结果显示,在10μg/ml以上浓度的内毒素作用18后或以100μg/ml浓度的LPS作用6h以上,淋巴细胞即可出现明显的凋亡形态学变化,表现为染色质凝集和周边化,核断裂,形成凋亡小体,DNA发生特异降解产生典型的"梯状"电泳图谱,呈现TUNEL阳性标记等,并通过流式细胞术证实这种凋亡具有时问和剂量的依赖性。

The spiny eel , belonging to Perciformes, Osteichthyes, is a kind of little freshwater fish distributed in Southern China. In 1998, Our lab detected XX/XY differentiated sex chromosomes in this specie with karyotypic analysis, and then with chromosomal binding and SC observation, we identified that its two largest metacentric chromosomes were X, Y sex chromosomes in 1999. X, Y chromosomes differ each other not only in the distribution of heterochromatin but also in their shapes, which make them could be recognized directly under the light-microscope without any banding treatment.

刺鳅,属鲈形目、刺鳅科(Perciformes,Mastacembelidae),是广泛分布于中国南方的小型淡水鱼类。1998年,我室通过核型分析,首次发现该物种具有明显分化的异形性染色体,其性别决定类型为XX/XY型。1999年,本室通过染色体显带、精母细胞联会复合体观察,再次确认刺鳅染色体组中最大的一对中部着丝粒染色体为X、Y性染色体,两者不仅已经出现结构异染色质分布上的不同,同时在外部形态上也存在明显差异,识别特征鲜明,在光镜观察下无需显带即能清晰辨认性染色体。

Cytology reveals cells with clear to lightly basophilic cytoplasm and round or indented nuclei with fine chromatin and indistinct nucleoli.

细胞学分析可见透明至浅染的酸性细胞质和圆形或缩进的细胞核含有正常的染色质和模糊的核仁。

Particular attention will bepaid in the field of gene expression regulation to high-throughput screening andidentification of cis-acting elements within the genome and to investigation ofinteraction manners of these regulatory sequences with regulatory proteins in theconditions of in vivo chromatin contexts.

如何在体内的染色质环境下,高通量、大规模地筛选与检测基因组内的顺式作用元件并研究其与反式作用因子间的相互作用,是当前和今后一个时期内基因表达调控领域内的研究重点之一。

In other words, researchers have to prove that the disruption of this function, either genetically through mutation, or epigenetically through DNA methylation or chromatin modification, causes the initiation or progression of cancer.

换句话说,研究人员必须证明这些功能的中断,或者是通过遗传上的突变,或者是通过表观上的DNA甲基化或染色质修饰,导致癌症的发生以及进一步恶化。

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This one mode pays close attention to network credence foundation of the businessman very much.

这一模式非常关注商人的网络信用基础。

Cell morphology of bacterial ghost of Pasteurella multocida was observed by scanning electron microscopy and inactivation ratio was estimated by CFU analysi.

扫描电镜观察多杀性巴氏杆菌细菌幽灵和菌落形成单位评价遗传灭活率。

There is no differences of cell proliferation vitality between labeled and unlabeled NSCs.

双标记神经干细胞的增殖、分化活力与未标记神经干细胞相比无改变。