染色质的

Euchromatin Network was created by John H. Frenster of USA. It is designed to help researchers and others interested in the latest developments in our studies of this most active part of the genome within the cell nucleus including Ultrastructural Probes of Active DNA Sites, and the RNA Activators of DNA.

该网络由美国人约翰·H·弗兰斯特创建，旨在为动植物染色质研究人员及对该领域感兴趣者提供有关细胞核中基因组研究的最新信息，包括激活位点的超级探针、DNA的RNA激活子。

In fact, the first evidence that histones might be involved directly in formation of heterochromatin was provided by the discovery that

SIR3的C端与核的蛋白质薄层有着相似性并且可以起将异染色质束缚在核周围的作用。

It contains the largest autosomal block of heterochromatin, which is heteromorphic in 6–8% of humans, whereas pericentric inversions occur in more than 1% of the population.

它具有最大的常染色体异染色质区域，其在6-8％的人群中为异型的，然而中心周围倒位在人群中出现率大于1％。

It showed that thymidine could have special effect on cells in that replication in cells suffering thymidine treatment slow down substantially but do not stop DNA synthesis. This phenominon of leakiness in replication blockage provided chances for oligonucleotide to mediate repair.

通过检测上述三种抑制剂作用于细胞后不同时间的细胞周期分布，发现thymidine在抑制DNA合成的同时，存在着缓慢的渗漏作用，即染色质DNA上复制叉缓慢移动。

RESULTS: There were many vacuoles and cracks in the cells, with heterochromatin margination, nuclear pycnosis and nuclear fragmentation. The high intensity pulsed electric fields caused damage in K562 cells, and the apoptotic percentage went up with the increase in frequency and intensity of PEF.

结果：经过高电压脉冲电场处理后的K562细胞，胞内出现大量空泡及裂隙，核内染色质向核周边聚集形成凋亡小体，呈典型细胞凋亡形态学改变；K562癌细胞的凋亡比例随着脉冲个数和电场强度的增加而增加。

Methylation is negative correlation with genetic transcription , and the mechanism is probably as follows : directly interfere the combination of specific transcripton and recognition site of each promoter ; mediated transcription inhibition by change the construction of chromatin; induced gene silencing by combination of methylation site and transcription inhibition. P16 gene is also called multiple tumor supresser gene , which is the best easily to methylate in the anti-oncogenes. P16 gene locates in 9p21 of mankind-chromatosome , and it's total length is 8.5kb .

甲基化与基因转录呈负相关，其机制可能是[3]：直接干扰特异的转录子和各自启动子识别位点的结合；通过改变染色质结构，介导转录抑制；甲基化DNA位点直接与转录抑制子结合，诱导基因沉默。p16基因又称为多肿瘤抑制基因( multiple tumor suppressor 1 ，MTS1) [4] ，是肺癌中最易发生甲基化的抑癌基因，该基因位于人类染色体9p21上，全长8.5kb ，由两个内含子和三个外显子组成。

As we know, SWI/SNF is a global, untargeted chromatin remodeler which influence transcription, it perform gene-specific regulation by interacting with some selective activators. On the other hand, no known DNA-binding domain is found in BEX1. So we come to a conclusion that BEX1 may mediate activators interact with hSNF5, and this result in the transcription of specific sets of genes that control the cell cycle.

由于BEX1本身并未发现能与DNA直接结合，而hSNF5所在的染色质重塑复合体单独存在时作用没有特异性，我们推测，BEX1可能作为接头分子，介导了其它蛋白与hSNF5的作用，导致控制细胞周期相关基因的转录激活或抑制。

According to the change of chromatin and morphology of cells, the spermatogenesis could be divided into five stages: spermatogonium, primary spermatocyte,secondary spermatocyte, spermatid and spermatozoon.

利用透射电镜观察秀丽白虾的精子发生，并根据染色质及细胞形态的变化将精子发生的全过程划分为五个时期，即精原细胞、初级精母细胞、次级精母细胞、精细胞和精子。

Most endothelial cells fell off, elastic fibre autolyze; the number of SMC decreased, some SMC nucleus contracted completely or depressed, typical apoptosis body were seen in later stage, muscle silk autolyzed and disappeared mostly; in outer layer saw much collagenic fiber, arranged unorderly; inflammation cells were seen in the aneurysm wall(hypertrophy cell et al.).

多数瘤壁的内皮细胞溶解脱落，不连续，弹力纤维自溶；动脉瘤血管壁均可见SMC明显减少，较多SMC染色质边聚、固缩，部分SMC核全部固缩或出现不规则凹陷，SMC核胞浆或胞核部分出现脱落或裂解成碎片，晚期可见典型的凋亡小体出现，肌丝大都自溶消失：外膜可见大量的胶原纤维，排列较紊乱；瘤壁还可见炎性细胞浸润。

Using tertiary trisomes and hypoploids of a set of B-10L translocations, the CL-repeat signals and the variants in each of the three distal heterochromatic regions were identified.

利用一系列的B-10L易位染色体所产生的三级三染体和亚倍体，可以判断CL-repeat讯号及其变异产物在三个远端异染色质区(DH1， DH2， DH3)上的分布位置。

Lugalbanda was a god and shepherd king of Uruk where he was worshipped for over a thousand years.

Lugalbanda 是神和被崇拜了一千年多 Uruk古埃及喜克索王朝国王。

I am coming just now,' and went on perfuming himself with Hunut, then he came and sat.

我来只是现在，'歼灭战perfuming自己与胡努特，那麼，他来到和SAT 。