染色质

In light and electronic microscopy, they appeared cell shrinkage, cell density increasing and eosinophilic, aggregation of cytoplasmic organelles, nucleolus fragmentation, and chromatin margination, condensation, and fragmentation. Those changes could be detected by TUNEL method.

在光镜和电镜下癌细胞凋亡表现为细胞体积缩小，胞浆浓缩嗜酸性，胞浆出泡、细胞器缩小或减少，核仁松解，染色质聚集、靠边、浓聚、断裂，在TUNEL法检测凋亡癌细胞时也可观察到相应的形态特点。

The ultrastructural changes of the embryos cell in group Ⅳ were observed by transmission electronmicroscope,which showed condensation of the nuclear chromatin with margination,mitochondria swelling.etc.

照射30 min组小鼠胚胎细胞电镜检查发现染色质浓缩边集、线粒体肿胀等超微结构变化。

Methylation is negative correlation with genetic transcription , and the mechanism is probably as follows : directly interfere the combination of specific transcripton and recognition site of each promoter ; mediated transcription inhibition by change the construction of chromatin; induced gene silencing by combination of methylation site and transcription inhibition. P16 gene is also called multiple tumor supresser gene , which is the best easily to methylate in the anti-oncogenes. P16 gene locates in 9p21 of mankind-chromatosome , and it's total length is 8.5kb .

甲基化与基因转录呈负相关，其机制可能是[3]：直接干扰特异的转录子和各自启动子识别位点的结合；通过改变染色质结构，介导转录抑制；甲基化DNA位点直接与转录抑制子结合，诱导基因沉默。p16基因又称为多肿瘤抑制基因( multiple tumor suppressor 1 ，MTS1) [4] ，是肺癌中最易发生甲基化的抑癌基因，该基因位于人类染色体9p21上，全长8.5kb ，由两个内含子和三个外显子组成。

All date above showed that SDG714 was involved in heterochromatin stability and the mechanism of histone methylation controlling DNA methylation was conserved in monocot.

表明SDG714影响异染色质的功能和染色体的稳定性，H3K9组蛋白的甲基化控制DNA的甲基化这一特性，在水稻中同样具有保守性。

The occurence of cytomixis or intercellular migrating chromatin substance exists widely in the pollen mother cell...

花粉母细胞间染色质穿壁转移现象在高等植物中广泛存在，但就其产生的原因素有争议。

In addition, ChIP assays showed that NaBu treatment increased the binding of Sp1 to ALAS2 gene promoter.

染色质免疫沉淀实验还发现NaBu的处理能增加ALAS2基因启动子上Sp1因子的结合。

They are often morphologically distinct from A chromosomes, being smallerand more highly heterochromatic in most cases. B chromosomes do not pair with Achromosomes, and they are inherited in a non-Mendelian way, exhibiting meiotic andmitotic instability and nondisjunction. However, B chromosome DNA is quiteidentical to the corresponding sequence on the A chromosome complement. So far afew B chromosome specific DNA sequence have been identified. Specific DNAsequences on B chromosome have been the attractive research area on Bchromosomes.

现已在千余种植物和近三百种动物中被发现。B染色体与物种中正常染色体不同：独立于整倍体基因组之外，减数分裂时不与A染色体发生联会和配对，细胞分裂后期不分离，非孟德尔遗传，富含异染色质，不含对宿主主要性状有影响的基因等。B染色体DNA的分子组成既与A染色体极为相似，具有A染色体DNA分子组成的一般特征：富含重复序列和转座成分，染色体三大功能组件DNA高度同源；又与之相区别，含有B染色体特异的DNA序列，这些DNA序列可以为探讨B染色体的起源和进化提供有价值的信息。

Generation of spheroplasts and chromatin hydrolysis with micrococcal nuclease.

代spheroplasts和染色质水解微球菌核酸。

Cells from control embryos consist of a nucleoid core with zero or minimal DNA migrating into the tail region, while cells from treated embryos with much more DNA migrating into the tail region.

染色质浓缩边集和分割是细胞凋亡的典型形态学变化，绝大多数凋亡细胞在电泳时会出现DNAladder，也是DNA片段化检测中较传统的方法。

Results:Typical apoptotic cellular changes were found after As2O3 treatment,transmission electron microscopy showed nucleole disappeared,chromatin condensated under nucleonic membrane.

结果：经As2O3作用后VSMCs出现典型的凋亡变化，透射电镜下可见细胞核仁消失，染色质浓缩聚集于核膜下。

This one mode pays close attention to network credence foundation of the businessman very much.

这一模式非常关注商人的网络信用基础。

Cell morphology of bacterial ghost of Pasteurella multocida was observed by scanning electron microscopy and inactivation ratio was estimated by CFU analysi.

扫描电镜观察多杀性巴氏杆菌细菌幽灵和菌落形成单位评价遗传灭活率。