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Histone acetylation and deacetylation are crucial in the regulation of gene expression.

组蛋白乙酰化和去乙酰化对基因表达的调控至关重要,基因表达的动态变化将会影响染色质的结构。

To extrahepatic cholangiocarcinoma and gallbladder carcinoma, the rate of excision is low and the sensitivity to chemotherapy and actinotherapy is poor.

我们的研究表明,胆道癌表遗传的改变能够通过对染色质基因转录的调节来影响癌细胞的增殖进程,而表遗传的改变与蛋白信号的传导密切相关。

In the treatment group, the bone cells were normal, the endoplasmic reticula were abundant and the cellular nuclei were of normal shape.

治疗组细胞正常,内质网丰富,细胞核呈正常形态;激素组骨细胞体积缩小,核固缩,染色质边聚,骨陷窝扩大。

The inducible type isolations and their constitutive type changers were put into the same group.

对每组细菌的质粒ampC基因和染色质ampD基因进行扩增、测序和序列比对。

In spermatids, there are many IFs and the NM is concealed beneath the clumps of chromatin.

精子细胞中,中间丝丰富,核基质结构被致密的染色质团簇所掩盖。

Results:Compared with the untreated fibroblast from hypertrophic scar, the rough endoplasmic reticulums were decreased, the ribosome were appeared degranulation and depolymerization and lysosomes were lncreased respectively.

结果:Mat可使增生性瘢痕成纤维细胞的超微结构发生变化;细胞内粗面质网减少,核糖体有部分脱粒、解聚现象,溶解体酶,核染色质浓缩集聚至核膜周边,出现凋亡早期的改变。

Most sperm nuclei eventually developed into the male pronuclei, just like the normal sperms, except sperm nuclei in a few zygotes kept dense throughout the fertilization process. Dense chromosome body was seen at the nuclear area during the prophase of first mitosis, and in the middle of spindle at metaphase of first mitosis.

精子入卵后形成精核,大多能够逐渐解凝、液化并膨大,最终形成形态正常的雄性原核,但在第一次卵裂早期退化成浓缩的染色质小体,并在胞质分裂时随机地分配到其中一个子细胞里的分裂沟附近。

After the ChIP assay was performed for phosphorylated Pol II using antibodies highly specific for certain phosphorylated serine residues of the CTD, the extension of short primer was carried out and then the samples were analyzed using matrix-assisted laser desorption ionization time-of-flight.

采用PCR-RFLP方法对HepG2细胞印迹基因SNRPN基因组DNA和cDNA进行基因分型,利用PolⅡ CTD末端Ser5特异性抗体进行染色质免疫沉淀,针对SNP位点两侧序列设计PCR引物和延伸引物,以外侧引物进行PCR扩增,采用延伸引物进行VLET引物延伸,产物纯化后经MALDI-TOF质谱鉴定。

Results After the treatment with 15 μmol·L~(-1) of evodiamine for(24 h,)A375-S2 cells exhibited typical characteristics of apoptosis:loss of membrane microvilli,cytoplasmic hyp...

结果经15μmol.L-1吴茱萸碱处理24 h的A375-S2细胞表现出典型的凋亡特征,即细胞表面微绒毛消失、胞质空泡化、染色质浓集、边聚。

Results: From the second days of the operation, the brain swellen overtly. RBC and phagocyte can be seen in the cerebral interstitial space. The adventitia of the brain arteries and the perivascular Virchow ̄Robin space dilated irregularly. The neuronal number of hippocampal CAI sector decreased evidently. In some neuron both the nucleus and cytoplasm condensed, chromatin gathered near the nuclear membrane.

结果: 自术后第二天可见脑组织水肿,红细胞溢出及吞噬细胞浸润,小血管壁外膜及Virchow ̄Robin间隙增宽,内含大量水肿液,海马CAI区正常神经元数量明显下降,且排列及不整齐,细胞皱缩,核固缩、深染,核染色质聚集,核周囊膨大,胶质细胞增生。

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你知道吗,我需要你回来

Yang yinshu、Wang xiangsheng、Li decang,The first discovery of haemaphysalis conicinna.

1〕 杨银书,王祥生,李德昌。安徽省首次发现嗜群血蜱。

Chapter Three: Type classification of DE structure in Sino-Tibetan languages.

第三章汉藏语&的&字结构的类型划分。