染色体结合

EDTA was used in plant together with other aberrant factors in order to increase the frequency of chromosome aberration.

EDTA的使用也多数是和其他诱变因素结合使用，以达到提高染色体畸变频率的目的。

Methylation is negative correlation with genetic transcription , and the mechanism is probably as follows : directly interfere the combination of specific transcripton and recognition site of each promoter ; mediated transcription inhibition by change the construction of chromatin; induced gene silencing by combination of methylation site and transcription inhibition. P16 gene is also called multiple tumor supresser gene , which is the best easily to methylate in the anti-oncogenes. P16 gene locates in 9p21 of mankind-chromatosome , and it's total length is 8.5kb .

甲基化与基因转录呈负相关，其机制可能是[3]：直接干扰特异的转录子和各自启动子识别位点的结合；通过改变染色质结构，介导转录抑制；甲基化DNA位点直接与转录抑制子结合，诱导基因沉默。p16基因又称为多肿瘤抑制基因( multiple tumor suppressor 1 ，MTS1) [4] ，是肺癌中最易发生甲基化的抑癌基因，该基因位于人类染色体9p21上，全长8.5kb ，由两个内含子和三个外显子组成。

The transcription-associated effects contribute to the overall skew through the uneven distribution of the coding sequences on the leading and lagging strands; the replication-associated effects, on the other hand, through the entire chromosome.

其中结合转录的效应对整体不对称性的贡献主要是藉由蛋白质转录序列在复制双股之间的分布所造成；结合复制的效应的贡献则遍及整条染色体。

Further, by in situ hybridzation with the same probe, it showed that the v ariant of the marker had specific autoradiographic silver grains.

结果表明，常规显带与染色体原位杂交等分子生物学技术相结合对于鉴定人类染色体的微小结构畸变具有重要的应用价值。

The gene controlling powdery mitdewresistance is preliminarily allocated on the H.villosachromosome 〓 by morphological and characteristic identifica-tion combined with cytogenetical analysis.

将性状鉴定与细胞学分析相结合，基本探明簇毛麦的V〓染色体上带有抗白粉病基因，控制簇毛麦护颖频脊簇状刚毛性状的基因在〓和〓染色体上。

Methods Cell cultures of8HNSCC cell lines were stained with haematoxylin and eosin,to analyze mitotic cells with anaphase bridge morphology.

用荧光结合 3 核酸探针以荧光原位杂交方法检测细胞分裂中期染色体末端端粒表达，计算平均每细胞中端粒缺失染色体末端。

Objective To study the technique and diagnostic value of fluorescence insitu hybridization in chromosome abnormality for prenatal diagnosis. Methods Amniocenteses were performed in 34 pregnant women of 16～23 gestational weeks with indications for prenatal diagnosis. The amniotic fluid samples were cultured in Chang's medium.

荧光原位杂交(fluorescence in situ hybridization， FISH)是分子杂交与组织化学相结合的一项新技术，近年来用于人类染色体分析，它能快速、准确地确定在传统方法中无法判别的染色体异常，特别对来源不明的标记染色体能作出正确诊断［1，2］。

SATB1 folds and remodels the chromatin -- the intertwined DNA and proteins that form chromosomes -- into new shapes, bringing even distant parts of the genome together for coordinated control of gene expression_r and regulation.

SATB1打开并重新改型这些染色体——使DNA和蛋白质缠绕而形成同源染色体——变成新的形状，使位置较远的基因组结合从而协调基因的表达和调控。

The aims of this dissertation is combining new theory and method about artificial neural network into numerical computing, cell genetics and chromosome banding technology, to solve the problem which is automatic analysis and recognition of high resolution band of plant chromosome and improve its analysis speed, quality, accuracy and automation.

本文研究的目的是将神经网络的新方法、新理论与计算数学、细胞遗传学和植物染色体分带学相互结合解决植物染色体纹理的高分辨带纹的自动分析与识别问题，提高其分析速度、质量、精度以及自动化程度。

Based on different DNA fragments between Z and W chromosome, the developed PCR method has no risk of the mistrial of those sex identification markers depended on W chromosome, and can omit extra internal control or restriction enzyme deigestion. The DNA-based spindlin gene approach can provide a rapid, exact and low cost method for sex identification in poultry.

本研究以PCR检测家禽Z与W性染色体中之纺缍体蛋白基因intron序列，以其长度的差异来鉴定家禽性别，可避免仅检测W染色体性别鉴定标记的误判，且不需再搭配内部对照，更不需结合限制酶切割法即进行家禽性别鉴定。

She gently rebuff ed him, but agreed that they could be friends

她婉言拒绝了，但同意作为朋友相处。

If in the penal farm, you were sure to be criticized.

要是在劳改农场，你等着挨绳子吧！