染色体组型的

The laboratory findings of a typical CCML patient comprised of peripheral blood leukocytosis, basophilia and eosinophilia,myeloid differentiation in different stages, and increased megakaryocytes. The immunohistochemical features of the CCML consisted of highly positive MPO and CD68, significant lowering of neutrophil alkaline phosphatase, positive for Philadel- phia chromosome or chimeric BCR/ABL gene, etc. But in most cases of juvenile CCML, the Philadelphia chromosome could not be detected.

临床表现以乏力、低热、贫血、肝脾及淋巴结肿大为主要特点；典型儿童慢性髓细胞白血病的实验室特点有白细胞计数高、嗜酸和嗜碱性粒细胞增多、骨髓不同阶段髓细胞分化和巨核细胞增多；免疫组化提示CD68，髓过氧化物酶，中性粒细胞碱性磷酸酶积分明显减低，Ph染色体或BCR/ABL融合基因阳性，而幼年型CCML的Ph染色体常为阴性。

The biosystematic relationship between two species of Nelumbo Adans.was studied by the method of karyotype analysis,genome analysis and silver-staining of interphase neclei in Nelumbo lutea Pers.

对莲属美洲黄莲和莲的3个品种的核型分析、染色体组分析和间期核银染，研究了莲属两个种的系统关系。莲属两个种的核型大致近似，均有2对具随体染色体。

One was the pqsA' positive expression plasmid constructed by cloning the pqsA'-lacZ fusion digested from pYHP441 into miniCTX-1, whose sequence was then integrated into wild type PAO-1 chromosome by biparental mating procedure. The other was pqsA-E operon knock-out plasmid whose sequence between pqsD and pqsE operon was inserted by tetracycline cassette by the site specific insertion mutagenesis strategy and the mutant constructed by biparental mating of S17-1 that harbored the plasmid and pqsA' positive expression mutant.

一种是酶切质粒pYHP441获得pqsA'-lacZ片段后，亚克隆入质粒miniCTX-1中，构建成PqsA'的阳性表达质粒，随后将构建的质粒，通过双亲交配过程整合入野生型铜绿假单胞菌株PAO-1染色体组中；另一种是通过点特异插入诱变策略，将四环素基因盒插入启动子pqsD和pqsE之间，构建的阴性质粒转化入大肠杆菌S17-1株后，和上述pqsA'阳性表达突变株进行双亲交配过程。

By using genome in situ hybridization on root somatic chromosomes of allotetraploid derived from the cross Gossypium arboreum × G.

然而，仅依据形态学和普通的核型图像，还不能确定该异源四倍体棉种中比克氏棉G染色体组在核型中的表现。

BACKGROUND: Retinitis pigmentosa is a group of commonest genetic blindness-inducing eyeground diseases, which have relative great heterogenicity in both heredity and phenotype. Pierce et al discovered a new retinal photoreceptor cell specific gene-RP1 in 1999, and also found in their following research that the mutation of this gene can induce autosomal dominant RP .

背景：视网膜色素变性(retinitis pigmentosa，RP)是一组最常见的遗传性致盲眼底病，在遗传和表型上均具有较大的异质性。1999年Pierce等发现了一个新的视网膜感光细胞特异基因--RP1，之后的研究发现该基因的突变可导致常染色体显性遗传RP(autosomal dominant RP，adRP)。

Amblycephala is composed of 13 metacentric chromosome pairs, 9 submetacentric chro-mosome pairs and 2 subtelocentric chromosome pairs, which can be expressed as 26m + 18sm+ 4st.

随着鱼类杂交育种研究的深人，染色体的组型研究也逐渐应用于预测杂交成功与否、杂种能否正常生育等方面。

Individuals with one X and no Y chromosome are phenotypically females but have a group of physical abnormalities including dwarfism and failure of ovarian development known as Turner's syndrome.

含有一个X而无Y染色体的患者表型为女性，但有一组机体异常表现，包括侏儒郑和卵巢不发育，称为Turner综合症。

In summary, the BRD7 gene acted as a candidate of tumor suppressor gene with NPC. The overexpression of BRD7 can partly reverse malignant phenotype of NPC cell line. The suppression effect of BRD7 on NPC tumorigenesis my be achieved by recognizing acetylated histone peptide through their motif-bromodomain, then modulating gene transcription by taking part in histone acetylating and chromosome remodeling, finally influencing signal-transduction pathways.

综上所述，BRD7基因作为一个重要的鼻咽癌抑瘤基因侯选者，在鼻咽癌细胞中的过表达后，可导致鼻咽癌细胞 HNE蛋白质表达谱发生改变，逆转其恶性表型，其作用机理可能是：BRD7基因通过其功能域彭聪硕士学位论文10Bromodomain与乙酚化的组蛋白特异性结合，参于染色体的乙酚化，染色质的组装，从而影响基因转录的调控，最终影响细胞内的信号传导通路并实现对细胞周期的调控，从而发挥抑制鼻咽癌细胞生长的作用。

The chromosome genomes of Deqin wild alfalfa variety (Medicago sativa L.), scattered alfalfa variety (AC-3) in Yunnan province and 8 foreign introduced cultivated alfalfas were classified and compared by karyotypic analysis.

以云南野生种紫花苜蓿、逸散种紫花苜蓿(AC-3)和8个国外引进栽培种紫花苜蓿为材料，采用核型分析方法对供试材料的染色体组进行了分类和比较。

The expression of some oncogenes in the cells was examined by means of chromosomal pattern analysis and immunohistochemistry.

应用染色体核型分析和免疫组化方法，分析原代细胞核型以及癌基因与抑癌基因的表达。

It has been put forward that there exists single Ball point and double Ball points on the symmetrical connecting-rod curves of equilateral mechanisms.

从鲍尔点的形成原理出发，分析对称连杆曲线上鲍尔点的产生条件，提出等边机构的对称连杆曲线上有单鲍尔点和双鲍尔点。

The factory affiliated to the Group primarily manufactures multiple-purpose pincers, baking kits, knives, scissors, kitchenware, gardening tools and beauty care kits as well as other hardware tools, the annual production value of which reaches US$ 30 million dollars.

集团所属工厂主要生产多用钳、烤具、刀具、剪刀、厨具、花园工具、美容套等五金产品，年生产总值3000万美元，产品价廉物美、选料上乘、质量保证，深受国内外客户的青睐