染色体基因

Haplotype is a lineable combination of alleles at multiple loci that are transmitted together on chromosome or mitochondrion.

单倍型是指一条染色体或者线粒体上紧密连锁的多个等位基因的线性排列，作为一个整体遗传给子代。

The poly- morphisms of XRCC1 G27466A and G28152A are not found to have association with abnormal chromosomes.

未发现XRCCl G27466A和G28152A基因多态性与辐射致染色体畸变有关。

Having the same alleles at a particular gene locus on homologous chromosomes.

在相应的染色体位点上具有同样的等位基因。

Karyotype analysis method is a basic technique in cytogenetics,cytotaxonomy and other related subjects.

核型分析是细胞遗传学、染色体工程、基因定位及细胞分类学等学科的基本研究方法[1]。

Relationship revealed by cytotaxonomy, which based on gene vector chromosome, is an improvement and examination of original classification and investigation of speciation mechanism and their evolution direction.

基于对基因载体染色体的研究，细胞分类学所揭示的类群之间的亲缘关系，可作为进一步审查、改进原来分类系统的依据，提示物种的形成机制和类群的进化方向。

Results The bone marrow slides showed faggot auer body stained Alcian blue positive in 8 of 21 patients contrast to none in the other 13 ones. Chromosomal abnormality of t(15; 17) and PML-RARa fusion gene were found in the bone marrow of the 8 patients, and among them 3 had additional chromosomal abnormality.

结果 阿利新蓝染色检测柴捆状Auer小体阳性8例，遗传学检查均显示t(15； 17)和PML-RARa融合基因，其中附加其他染色体异常3例。

Detected by FISH technology, 34 cases(85%) were BCR/ABL positive, 6 cases(15%) were BCR/ABL negative.

应用FISH技术检测，BCR/ABL融合基因阳性34例（含14例Ph染色体阴性中的8例），占85%；BCR/ABL阴性6例，占15%。

The effects of curcumenol on induction of differentiation of K562 cell line may be due to its prevention of chromosome damage and decreasing of bcr/abl gene mRNA expression.

莪术醇对畸变的K562细胞染色体有作用，影响bcr/abl融合基因的表达，使K562细胞向成熟分化。

For maintain the genome integrity and fidelity. DNA repair processes are classified into pathways responsible for repairing specific classes of DNA damage, although recent data indicated that some proteins function in multiple pathways. Base excision repair occurs through excision of a damaged region, followed by fill-in repair synthesis using the opposite strand as a template. Mismatch repair operates on base mismatched and small loop-outs that arising during replication by misincorporation or slippage on the template strand. Nucleotide excision repair removes photoproducts from u.v. radiaton and bulky adducts from a multiple of chemicals. DNA double-strand breaks may be rectified by either homologous recombination repair and nonhomologous end joining pathways where both strands of the DNA duplex are damaged.

DNA修补基因可藉由不同的机制对不同程度的DNA损害进行修复，虽然近来已有文献指出，一些DNA修复蛋白可能参与多种DNA修复机制，不过一般可分为下列四种DNA修复机制：碱基删除修复(Base Excision Repair； BER)，即对较小的DNA损伤，进行修复；核苷酸错误配对删除修复，即对复制时所产生的核苷酸配对错误或模板滑动造成的DNA损害进行修复；核苷酸删除修复(Nucleotide Excision Repair； NER)，即对因紫外线或有机化合物所造成的较大损伤进行修复；以及双股DNA断裂修复(Double-Strand Breaks； DSBs)，即对双股DNA断裂进行修复，此机制又可分为同源染色体的重组与末端接合两种主要路径，对受损的DNA进行修复。

The chromosome manipulation of thess genes was also discussed.

文章还就这些基因的染色体操作等进行了讨论。

In the United States, chronic alcoholism and hepatitis C are the most common ones.

在美国，慢性酒精中毒，肝炎是最常见的。

If you have any questions, you can contact me anytime.

如果有任何问题，你可以随时联系我。