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染色体基因

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The open reading frame of Spinacia oleracea Betaine Aldehyde Dehydrogenase was retrieved from Spinacia oleracea and inserted into the Agrobacterium tumefaciens binary vector pBin438, which was driven by CaMV35S promoter, and produced the new binary vector pBSB. A. tumefaciens LBA4404 carrying this plasmid was used in genetic transformation of plants. Forty-five primary transgenic plants were detected by PCR and verified by the Southern blotting from 65 regenerated plants, of which 27 transgenic plants had only one copy of T-DNA.

摘 要:分离出菠菜甜菜碱醛脱氢酶基因构建成由CaMV35S驱动的双元植物表达载体pBSB,农杆菌菌株LBA4404携带该载体转化棉花,获得转基因棉花植株。65株转基因植株经过PCR筛选、Southern blotting分析证明有45株为成功的转化株,外源基因已经被整合到棉花的染色体组中,并以单拷贝插入居多。

Spinocerebellar ataxias are a clinically and genetically heterogeneous group of neurodegenerative disorders.

第一部分 SCA家系致病基因定位第一章一个新的SCA家系致病基因定位脊髓小脑型共济失调(spinocerebellar ataxias,SCA)是一种具有高度临床和遗传异质性的神经系统退行性疾病,多呈常染色体显性遗传。

The hepatocyte growth factor receptor is encoded by the proto-oncogene c-met, which can be uncongenially activated through a chormosomal rearrangement that creates a hybrid oncogene tpr-met.

c-met是一种原致癌基因,其蛋白产物为肝细胞生长因子接受体,透过染色体转位可产生具致癌性融合基因tpr-met。

Allelic loss at specific chromosomal loci is a common genetic alteration in human tumours and is thought to be critical for unmasking the recessive genetic changes for tumorigenesis.

人类食管癌的基因丢失研究染色体上座位特异性等位基因丢失是人类肿瘤基因组中一个普遍的遗传改变现象。

Based on the cDNA sequence of the zfh -1 gene in Drosophila , a novel human homolog located on chromosome 9 was found by computer cloning method.

利用果蝇心脏发育基因 zfh-1的 c DNA序列和计算机克隆方法,在 9号染色体上发现了一个新的人类同源基因。

The qualitative and quantitative analysis of schizophrenia and single nucleotide polymorphism of catechol-O-methyltransferase , Proline Dehydrogenase and DYSBINDIN genes were done by using transmission disequilibrium test . Results:(1) The symptoms of first-episode schizophrenia were divided into four independent symptom dimensions: psychomotor poverty, reality distortion, disorganisation and depression-anxiety.

4采用传递不平衡检验、单倍型传递不平衡检验和定量性状传递不平衡检验的方法对6号、22号染色体上3个候选基因,即儿茶酚氧位甲基转移酶(catechol-O-methyltransferase,COMT)、脯氨酸脱氢酶(Proline Dehydrogenase,PRODH)和DYSBINDIN基因的9个单核苷酸多态性(single nucleotide polymorphism,SNP)位点与精神分裂症、神经认知功能、人格特质和临床症状表现的关系进行了定性和定量的遗传学分析。

In this work, the semi-dwarfing gene sd-t was mapped between RFLP markers R514 and R1408B with the genetic distance of 1. 1cM to R514, of 4. 5cM to R1408B, by using the F2 population derived from crosses between Aitaiyin-2 and B30 (a null-lingual marker gene series). A connoting spanning between R514 and R1408B was constructed by screening the BAC library constructed from an Indicia variety, IRBB56, with these two markers.

本研究还利用矮泰引—2和无叶舌标志基因系B30杂交产生的包含474个单株的F2群体将籼稻半矮秆基因sd-t定位在第4染色体上RFLP标记R514和R1408B之间,距R514和R1408B的遗传距离分别为1.1cM和4.5cM。

To establish time-efficient and sensitive method for detection of the methylation of FMR1 and XIST genes,genomic DNA was deaminated by sodium bisulfite.

建立一种快速、灵敏的检测脆性X智障基因(fragile X mental retardation,FMR1)、X染色体失活基因(X chromosome inactivation,XIST)甲基化的方法。

"In the past there has been a lot of emphasis on chromatin modifications and physical access to genes, but Scp1 regulates the activity of the enzyme that transcribes genes directly," he adds.

在过去大家都强调染色体的修饰以及到达基因的物理途径,但Scp1却能直接调节转录基因酶活性。

The researchers trawled through more than 1,000 peer-reviewed medical publications that linked genes and chromosome regions to drug addiction over the past 30 years and assembled a list of 1,500 addiction-related genes.

研究者搜集了过去卅年来,与导致药瘾的基因以及与染色体相关的一千多份医学著作,并列出一千五百个可能导致药瘾的基因。

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