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染色体基因

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Allele One of the possible forms of a given gene.

等位基因:在同源染色体上占据相同座位的两个不同形式的基因。

ThyA. ctxB was also cloned in this plasmid to elicit anti-toxin immunal response. This improved vaccine candidate derived from IEM101 is named IEM108.which can elicit both antibacterial and antitoxic immunity.

并采用以管家基因thyA为选择压力的质粒-染色体致死平衡系统使之稳定表达,构建生物安全的抗菌抗毒基因工程活菌苗,该菌苗株命名为IEM108。

ABSTRACT] Objective To observe the efficacy and side effects of combined therapy with alltrans retinoic acid, arsenic trioxide (As2O3) and chemotherapeutics for newly diagnosed acute promyelocytic leukemia.

急性早幼粒细胞白血病是急性髓系白血病中的一种独特类型(M3型),以特异的染色体易位t(15,17)(q22,q21)为特征,形成PMLRARa融合基因,该融合基因是APL发病的分子基础和分子标志。

BACKGROUND: Neonatal-onset multi-system inflammatory disease, a rare autosomal dominantly inherited disease, belongs to a growing spectrum of autoinflammatory diseases, is characterized by urticarial rash, arthropathy, and chronic aseptic meningitis, and is associated with mutations in the cold-induced autoinflammatory gene, CIAS1, the gene that encodes the protein, cryopyrin.

背景:新生儿开始发病的多系统炎性病是一种罕见的常染色体显性遗传性疾病,属于自身炎性疾病逐渐庞大的范畴,表现特征为荨麻疹、关节病和慢性无菌性脑膜炎,它合并有冷刺激诱发的自身炎性基因 CIASI 的突变,该基因是编码蛋白质和 cryopyrin 。

A referencing flock comprsing eight paternal half-sib families totaling 374 individuals from Liangshan semi-fine wool sheep was utilised to analyze the allele frequency, polymorphism information content and heterozygosity of nine microsatellite from 2~ chromosome of sheep genome.And the research based on the daughter design to locate the putative QTL affecting wool traits was carried out in the linkage framework-mapping of 2~ chromosome.

本研究利用凉山半细毛羊的8个父系半同胞家系共374个个体,分析了绵羊基因组2号染色体上9个微卫星标记的等位基因频率、多态信息含量和群体杂合度,利用已构建的凉山半细毛羊2号染色体遗传连锁框架图谱,采用女儿设计对影响凉山半细毛羊8个羊毛性状的数量性状位点进行了定位研究。

The egg production of a week et al was also analyzed . 18 pairs of microsatellite primers were screened from chromosome 1 and chromosome Z, the primers were designed to allow optimal performance of the markers, in sets containing multiple microsatellites, on ABI3100 sequencers. We determined there were correlation among 13 microsatellite markers and 19 characters in 25 egg traits through least square means. At the same time, we calculated correlation among characters of egg traits in silkies.

从鸡1号染色体和Z染色体上筛选出18对微卫星标记,进行多重PCR扩增,并对引物组合的反应体系进行优化,在F1群体中检测到13个标记位点分别与25种性状中的19种性状有不同程度的相关,并进行同一标记不同基因型间的多重比较,同时还计算了产蛋性状间的表型相关。

Based on different DNA fragments between Z and W chromosome, the developed PCR method has no risk of the mistrial of those sex identification markers depended on W chromosome, and can omit extra internal control or restriction enzyme deigestion. The DNA-based spindlin gene approach can provide a rapid, exact and low cost method for sex identification in poultry.

本研究以PCR检测家禽Z与W性染色体中之纺缍体蛋白基因intron序列,以其长度的差异来鉴定家禽性别,可避免仅检测W染色体性别鉴定标记的误判,且不需再搭配内部对照,更不需结合限制酶切割法即进行家禽性别鉴定。

Scott Hawley, a genetics researcher at the Stowers Institute in Kansas City.

人类在绘制基因图谱时Y染色体显示的结果让它遭到了很多的批评,但显然Y染色体有反击的毅力和能量。

Classical genetic analysis suggested that Gl_2 was located in the chromosome 12, therefore Gl_2~e as its multiple alleles also located in the Chr 12 in cotton.

经典遗传学研究表明,Gl_2位于棉花第12染色体,因此作为它的复等位基因Gl_2~e也应位于棉花第12号染色体。

Mapping quantitative trait loci was undertaken base on the constructed molecular linkage map of this population. Two QTLs (qDR-5 and qDR-12) for drought tolerance were identified, they were in the region of GA41-GA257 on chromosome 5 and RG457-Y12817R on chromosome 12, respectively.

利用该群体的分子连锁图谱进行数量性状座位区间作图分析,共检测到2个耐旱的QTL(qDT-5和qDT-12),分别位于第5染色体的GA41-GA257之间和第12染色体的RG457-Y12817R之间,这两个QTL的加性效应均来自ZYQ8的等位基因。

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