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Telomere, a complex structure present at the ends of eukaryotic chromosomes, consists of tandam arrays of highly conserved hexameric repeats in vetebrates. Its function is to protect DNA from degradation of deleterious recombination.

端粒是由许多简单重复序列及相关蛋白组成的染色体末端复合结构,端粒酶是具有逆转录酶特性的核糖核蛋白复合物,能以自身的RNA为模板合成端粒重复序列,加至新合成的DNA链末端,维持端粒平衡从而保证染色体末端结构完整性及解决末端复制问题。

There are 11 gene bindings disappear in the normal group, but appear in the model group, and then disappear in the treat group, that indicates the 11 gene bindings are correlated with the epilepsy and Caohuozhimutang. After searching in the Gene Bank, 7 bindings in the 11 gene bindings are homogenic with the 8q31 ribosomal protein gene, 15p12 paraneoplastic neuronal antigen gene, 4q22 diacylglycerol kinase iota gene, xq37 FMR2 protein and 11p11 roudabout homolog 1, and 4 bindings of which are novel gene.

经NCBI美国国家基因库检索,这11条基因中的7条已知基因分别与位于鼠染色体8q31位置的核糖体蛋白、15p12位置的周围肿瘤神经元的抗原(paraneoplastic neuronal antigen)、4p22位置的甘油二酯酶、xq37位置的FMR2蛋白(FMR2 protein)的基因以及以及位于果蝇染色体11p11位置的交叉同族体(roundabout homolog 1)有极高的同源性;有4条基因片段同源性较低,为功能未知的新基因,已经在GeneBank进行了注册,注册号分别CK325391、CK325392、CK325393、CK325394。

In mice, Zanthoxylum bungeanum and lower dosage (500,1000mg/kg) of Illicium verum , Cinnamomum japonicum do not damage the bone marrow cell chromosome. But in high dosage, the Zb can inhibit the bone marrow cellproliferation, and the Iv and Cj can at different degree influence the stability of bone marrow cell chromosome.

花椒组和低剂量的八角、桂皮对小鼠骨髓细胞染色体没有损伤作用,高剂量花椒对小鼠骨髓细胞的增殖有一定抑制作用,高剂量八角、桂皮对小鼠骨髓细胞染色体的稳定性有不同程度的影响。

The result showed that lamin B recruited to the chromosome gradually after 6-DMAP was added into the culture solution.

此外,我们采用免疫荧光染色观察PM胚胎核膜重现过程中核纤层蛋白B的动力学变化,结果显示:在加入6-DMAP后核纤层蛋白B在染色体周围逐渐聚集,约3h后核膜完全形成,此时核纤层蛋白B在染色体周围的聚集达到最高峰。

The Guardian can reveal that a team of 20 top scientists assembled by Mr Venter,led by the Noble laurate Hamilton Smiith,has already constructed a synthetic chromosome,a feat of virtuoso bio-engineering never previously achieved.Using lab –made chemicals,they have painstakingly stitched together a chromosome that is 381 genes long and contains 580,000 base pairs of genetic code.

家长可以显示一个20人的团队的顶尖科学家通过文特的带领下,高贵的laurate汉密尔顿Smiith,已经建造了一个合成染色体,这一壮举的演奏家生物在以前从未达到使用化学实验室,他们之前在刻意的染色体缝长和包含381基因遗传密码的580,000降到了现在的碱基对。

Genetic heredity experiments showed that the inheritance of the melanic characteristics was incomplete dominance and autosomal and followed the Mendalian law.

结果表明,SEM蛹黑化性状的遗传是不完全显性遗传,遵循孟德尔的不完全显性遗传规律,控制黑化性状的基因位于常染色体上,与性染色体无关。

Results Free MMC 0.15625~5.0μg/kg significantly increased the positive rate of PCE micronuclear test, the chromosome aberration rate and rat teratogenecity, but the mitomycine C absorbed onto ACNP did not increased these heredity and proliferation toxicological indexes in a dose range of 0.625~10.0μg/kg.

结果 游离丝裂霉素腹腔注射0.15625~2.5μg/kg 均可导致小鼠骨髓微核试验阳性率和CHL染色体畸变率,用纳米活性炭吸附MMC后给药,在0.625~20.0μg/kg 腹腔注射后都没有明显增加微核试验阳性率和染色体畸变率。

Using count the leave.and flow cytometric to identifiy ploidy levels for the regenerated plants derived from antherculture in burley tobacco in this article,it shows that using count the chloroplast method could identify the ploidy levels simply and economic but it cannot identify the mixoploid accurately, so it easily lead to misidentify.

本文分别用气孔保卫细胞叶绿体计数和流式细胞仪两种方法来鉴定花药培养再生植株染色体的倍性,结果发现叶绿体计数法可以简单经济的检测烟草花药培养再生植株的染色体倍性,但它不能准确地鉴定出混倍体植株,易造成误判。

By chromosome counting, the detected hybrids were mixoploid.

通过染色体计数,发现所检测杂种为混倍体,同一植株的细胞有多种染色体数目构成。

The results of Fiber-FISH test in maize indicated that the hybridization signal was the extended moniliform long chain, the length of telomere DNA in each chromosome of maize was 7~103 μm and the copy numbers of the repeated sequences of telomere among each chromosome had significant differences (15~230 kb).

玉米的Fiber-FISH试验结果表明,杂交信号为伸展的念珠状长链,玉米各条染色体端粒DNA的长度为7~103μm,各染色体端粒重复序列的拷贝数存在显著差异(为15~230 kb)。

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