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Segregation Distorter is a meiotic drive system of natural occurrence. Heterozygous SD/SD+ males transmit the SD chromosome in vast excess over the normal homolog.

黑腹果蝇中的分离变相因子[Segregation Distorter]是一种非常典型的具有减数分裂驱动性质的特殊遗传因子。

LyBase is the primary resource for molecular and genetic information on the Drosophilidae.

LyBase是关于果蝇分子和遗传信息的主要资源。

"Enhancer trap" is an important technique to build and explore Drosophila brain gene expression pattern and its database.

&增强子陷阱&技术是建立果蝇脑全基因组表达图谱及其数据库的重要方法。

Homology modeling of 3-D structure of two AChE from L.entomophila were constructed using H.sapiens(1p0i:A) native BuChE structure and Drosophila melanogaster(1d×4:A) native AChE structure as templates,respectively,by SWISS-MODEL.The catalytic triad were found and denoted in the 3-D structure of AChE from L. entomophila referring to T.californica.2.2 Gene cloning ofβ-actin and mRNA expression levels of two AChE genes from L. entomophilaBecause no reference gene has ever been used in Real Time PCR for L.entomophila in GeneBank,a fragment ofβ-actin gene was cloned from L.entomophila(GenBank Accession No.: FJ041117).It consists of 822 bp encoding a protein of 273 amino acids residues.

利用蛋白质结构同源建模工具,分别以人丁酰胆碱酯酶(1p0i:A)和果蝇乙酰胆碱酯酶(1d×4:A)的蛋白晶体结构为模板,对嗜虫书虱2个AChE的三维结构进行同源建模,并在三维结构中发现了AChE的酶解活性位点,证明嗜虫书虱体内也存在2个AChE基因。2.2嗜虫书虱β-actin基因克隆及乙酰胆碱酯酶基因mRNA表达水平研究目前关于嗜虫书虱的分子生物学研究较少,在GenBank中没有可用作内参基因的序列,因此本研究从嗜虫书虱体内克隆获得β—actin基因片段(GenBank登录号:FJ041117),该片段长度为822 bp,编码273个氨基酸残基,同源性比对分析表明该片段与其它昆虫的β—actin基因具有很高的同源性。

The results of Pharmacodynamics experiments showed that thelife-span of the eumenid fed with TDR.TDR effect on the white rats'LPO,SOD and its' immunity, strength, irreitability, memory gained.

药效学试验通过喂饲天地人口服液对果蝇寿命试验的影响,天地人口服液对大白鼠过氧化质和超氧化物歧化酶活性的影响,以及天地人口服液对小白鼠免疫功能、体力及应激,体内脂质过氧化的作用。

The result showed "TDR" can prolong the average and highest 1ife-span of the eumenid; it also reduced the serum; liver and brain tissue's Lpo from the white rats 'obviously, at the same time, it build up the immunity, anti-stress, endures anoxia. To do so, the dosage of the "TDR" is crucial enableto achieve the clinical effectiveness.

结果表明:天地人口服液能延长果蝇平均寿命和最高寿命,能明显地降低大白鼠的血清、肝、脑组织的LPO,同时提高血清SOD的活性,并且有增强小鼠免疫功能、抗疲劳、耐缺氧,其药效与剂量有关。

Bioinformatics Analysis of Silkworm Development-Related Genes According to sequence homology, homologous genes for 86 genes participating in embryonic development genetic hierarchy of Drosaphila were searched in silkworm genome, including 43 maternal genes, 12 gap genes, 9 pair rule genes, 13 segment polarity genes and 9 homeotic genes. Results show that all but 6 maternal genes have the homologues in silkworm genome and some of them have high similarity.

家蚕发育相关基因的生物信息学分析基于序列的相似性,在家蚕基因组数据中检索参与果蝇胚胎发育调控级联的86个重要基因的同源基因,结果表明,除6个母性基因在家蚕中没有找出同源基因外,其余基因在家蚕中均存在同源基因,并且其中一部分具有相当高的相似性。

There are 11 gene bindings disappear in the normal group, but appear in the model group, and then disappear in the treat group, that indicates the 11 gene bindings are correlated with the epilepsy and Caohuozhimutang. After searching in the Gene Bank, 7 bindings in the 11 gene bindings are homogenic with the 8q31 ribosomal protein gene, 15p12 paraneoplastic neuronal antigen gene, 4q22 diacylglycerol kinase iota gene, xq37 FMR2 protein and 11p11 roudabout homolog 1, and 4 bindings of which are novel gene.

经NCBI美国国家基因库检索,这11条基因中的7条已知基因分别与位于鼠染色体8q31位置的核糖体蛋白、15p12位置的周围肿瘤神经元的抗原(paraneoplastic neuronal antigen)、4p22位置的甘油二酯酶、xq37位置的FMR2蛋白(FMR2 protein)的基因以及以及位于果蝇染色体11p11位置的交叉同族体(roundabout homolog 1)有极高的同源性;有4条基因片段同源性较低,为功能未知的新基因,已经在GeneBank进行了注册,注册号分别CK325391、CK325392、CK325393、CK325394。

Furthermore, a genetic screen was carried out to identify modifiers of the phenotypes associated with the constitutive expression of a dominant negative kuz transgene in developing imaginal discs.

另外,根据能否改变突变型kuz基因在器官芽中过量表达引起的表型,我们对覆盖了果蝇25%必须基因的2383个P因子插入突变进行了遗传筛选。

When the frequency of codon usage of citrus was compared to Homo sapiens, Drosophila melanogaster, Saccharomyces cerevisiac and Escherichia coli, we found that the codon preference is considerably different between citrus and non-plant species. While compared to Arabidopsis thaliana, Lycopersicon esculentum, Oryza sativa and Musa acuminata, we found that the codon preference was identical in dicotyledons, but was different between citrus and monocotyledon, Oryza sativa and Musa acuminate.

将柑橘的密码子使用频率与人、果蝇、酵母和大肠杆菌等不同种类模式生物比较后发现,柑橘密码子的偏爱性与不同种类生物有不同程度的差异;但将柑橘的密码子使用频率与拟南芥、番茄、水稻和尖叶蕉等不同种类的植物相比,发现柑橘密码子的偏爱性与同为双子叶植物的拟南芥、番茄完全一样,而与水稻、尖叶蕉这2种单子叶植物均有较大的差异。

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