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The results of in situ hybridization and fluorescence quantitative PCR showed that the gene expression of dopamine receptors(including D1 and D2) in the prefrontal cortex and DRD1 in lentiform nucleus of SHR from the Kongsheng Zhenzhong Pill group is higher than that in the methylphenidate hydrochloride group and both groups are lower than that in the control group:the gene expression of dopamine receptors D2 in the lentiform nucleus from the methylphenidate hydrochloride group is higher than that in the Kongsheng Zhenzhong Pill group while both groups are lower than that from the control group.

原位杂交和荧光定量PCR表明,SHR大鼠前额叶皮质的多巴胺受体(包括D1和D2)和豆状核受体D1的基因表达,孔圣中丹组比盐酸哌甲酯组要高,且两者均低于对照组;豆状核多巴胺受体D2的基因表达,盐酸哌甲酯组要比孔圣中丹组高,且均低于对照组。

We didn\'t find activated points in cerebellum and deeper brain.3.Acupuncture of sham point can significantly activated BA2,6,8,13,21,37,40,44,45,47,putamen and other areas.Both the left and right side of the brain have activated points,but points on the right side are more than those on the left.Both sides of middle temporal gyms,parietal lobule,supramarginal gyms and the lentiform nucleus have obvious activated points.The activated points mainly concentrated in the cerebral cortex,the deep-activated are mainly in the putamen.4. Sham needling in sham point can significantly activate BA6, 8,9,10,18,21,37,40,43,44.The activated points are mainly distributed in the right side of the brain.The left side also has some activated points;5.In the comparasion of Acupunture and sham-needling in S J5,we find that BA8 and cerebellum have distinct regional activated points;6.In the comparasion of acupuncture in SJ5 and sham point,we find BA2 and left cerebellar regions have activated points;7.Sham needling in S J5 compared with sham point,we find BA7,8,9,18 and other areas have activated points,the main activated points are at the left brain.It is not difficult to find that the distribution of activated points are mainly in the middle brain,no obvious activated points at the temporal lobe.

结果:通过对数据的处理和分析,我们初步发现:1、外关穴真针刺能显著激活Brodmann area45、37、44、40、22、13、37、47区、海马、杏仁核、黑质等区域,小脑左侧更明显,左侧颞叶皮层激活点多于右侧,且脑部左侧深层激活点多于右侧;2、外关穴假针刺能显著激活BA46、44、41、13、40、37、19区等区域,激活点主要集中表现在大脑皮层,以颞叶为主,小脑及深部未发现明显激活点;3、非穴真针刺组结果分析初步表明,BA2、6、8、13、21、37、40、44、45、47区以及壳核等区域有激活点,大脑左、右侧均有激活点,但右侧更多,双侧颞中回、顶叶下小叶、缘上回及豆状核有明显激活点,激活点主要集中在大脑皮层,深部激活点主要在壳核;4、非穴假针刺能显著激活BA6、8、9、10、18、21、37、40、43、44区等区域有激活点,主要分布在大脑的右侧,左侧也有不少激活点,就其具体分布主要在颞叶和额叶,少部分分布在顶叶和叶;5、外关穴真针刺与假针刺对比发现,BA8区和小脑等区域有明显的激活点;6、外关穴真针刺与非穴真针刺对比发现BA2区、左侧小脑等区域有激活点;7、外关穴假针刺与非穴假针刺对比发现,BA7、8、9、18等区有激活点,主要反应点在左侧大脑的叶中回、楔叶,顶叶楔前叶及额上回、中回,就其分布不难看出主要在大脑中部,颞叶未见明显激活点。

Objective To introduce and evaluate the clinical application of Cervifix internal fixation system and allogeneic freeze drying,radiation sterilization bone sheet in craniocervical fusion surgery for occipitocervical instability patients.

目的 介绍Cervifix颈内固定系统及同种异体骨板在颈融合术中的应用并评价其疗效。

Objective To introduce and evaluate the clinical application of Cervifix internal fixation system and allogeneic freezedrying,radiation sterilization bone sheet in craniocervical fusion surgery for occipitocervical instability patients.

目的 介绍Cervifix颈内固定系统及同种异体骨板在颈融合术中的应用并评价其疗效。

Objective: To clarify the technical parameters in posterior atlanto-occipital transarticular screw fixation and discuss the clinical significance of occipitocervical junction fixation with transarticular screws.

目的:明确后路寰关节经关节螺钉固定的技术参数;探讨颈部经关节螺钉内固定技术的临床意义。

Direction and length of trajectory are the key of posterior atlano-occipital transarticular fixation, if combined with C1-C2 transarticular fixation, it will be an ideal fixation method for occipitocervical fusion.

关节后路经关节螺钉植入存在一定的方向性和钉道长度,结合后路C1-C2经关节螺钉内固定后可视为能满足当前临床需要的一种相对理想的颈融合内固定术式。

The osteofibrous apertures,osteofibrous canal and the tendious decussating fibers of the nuchal muscles passed through by the greater occipital nerve are the anatomic basis of the greater occipital nerve compression syndrome.

大神经穿行的骨性纤维孔、纤维管道及项部肌群的腱性交叉纤维对神经的固定作用,是颈部运动或组织劳损时造成大神经卡压的解剖学基础。

The osteofibrous apertures,osteofibrous canal and the tendious decussating fibers of the nuchal muscles passed through by the greater occipital nerve are the anatomic basis of the greater occipital nerve compression syndrome.

大神经穿行的骨性纤维孔、纤维管道及项部肌群的腱性交叉纤维对神经的固定作用,是颈部运动或组织劳损时造成大神经卡压的解剖学基础。中国诺宇综合网http://www.siaaa.com

T1-weighted coronal sections show gadolinium enhancement along cortical gyri and sulci in the occipital paracentral cortex.

冠位增强T1像于叶旁中央灰质处见沿皮层脑回、脑沟的强化病灶;左侧叶距状裂皮层也见轻度强化病灶(最后1张图片)。

Results When lesion was located in the spinal cord ventrally and olivo ponto OPCA cerebellar atrophy, the evoked potentials N30, P40 from C2 and occiput after stimulating tibial nerve showed simultaneously abnormal.

结果 脊髓腹侧及小脑病变可致胫神经刺激,C2、点 N30及P40电位出现同步性异常改变,且胫神经刺激出现异常者,正中神经刺激,C2、点电位却可保持正常。

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