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It was found that the change of surface potential of the purple membrane resulting from acetylation induced the change of local protein conformation Which could be delocalized all over the protein to a great extent and affected the nature of binding sites of retinal and the structure of the retinal chromophore.

结果表明:酰化引起的表面电位的改变诱导了蛋白局部构象的改变。这种改变在很大程度上离域到整个蛋白分子中而影响了视黄醛结合位点的性质及生色团的结构,从而导致可观察的光谱变化。

Based on the relationship between the structure and function, a lot of research have been performed on predicting base-pair which is indispensable to the RNA three-dimensional strcutrue. The tools and methods in Combinatorics and Statistics will play important roles in studying linear sequences of biomolocular units . Similarly, we can present the geometric representation of biological sequences and structures. So the genometric topology and group theory are important also.

根据RNA的结构与功能的关系,在预测碱基配对的类型方面进行了相当多的研究,这也是确定RNA三维构象的必不可少的一部分,组合学和统计学的工具和方法在研究生物序列和生物结构上起到了很大的作用,同样我们可以用几何方法来表示生物序列和二级结构,几何拓扑和群论也起到了很大的作用。

They are not only involved in the process of fungal development and differentiation, such as supplying nutrition, for the growth of mycelium, attaching themselves to the morphosis and alteration of the cell wall of hyphae, as well as taking part in autolysis of filamentous fungi, but also show an important role in the process of pathogenesis including touching and cling on to the cell wall o.

1,3-葡聚糖酶(β-1,3-glucanase)是一类能够水解β-1,3-葡萄糖苷键的酶,普遍存在于多种真菌中,它们不仅在真菌生长发育起重要作用,如为菌丝体生长提供营养、参与菌丝体细胞壁的形态建成和构象的改变、参与菌丝体自溶等,而且在病原菌入侵寄主植物与致病的过程中扮演着重要角色,如:参与接触和吸附寄主细胞壁;破坏包围病原菌入侵结构的乳突。

The increase in fluorescence intensity and the red shift in emission peak were the indicators of enzyme inactivation.

萤光强度的增加和最大发射峰位的红移是酶变性失活的一个指标,酶活力的变化快于酶分子整体构象的变化,说明麦芽酸性磷酸酶的活性部位位於柔性较大的区域。

We will look at two studies that address the 3-dimensional conformation of the native prion protein and the infectious scrapie state using cryoEM and X-ray crystallography.

我们将探讨两个分别使用低温电子显微镜和X射线结晶法阐明了自然状态下的朊蛋白和传染性的瘙痒病状态下的朊蛋白的三维构象的研究。

Optimized and calculated geometric structure and infrared spectrum of benzoic acid molecule with density functional B3LYP method on 6-311G ** base cluster level,and compared the calculated infrared frequency of each conformation of benzoic acid with actually-measured infrared spectrum,thus determined molecula.

用密度泛函 B3LYP方法在6-311G**基组水平上对苯甲酸分子的几何结构和红外光谱进行了优化和计算,并将计算所得的苯甲酸各构象的红外频率与其实测的红外光谱进行比较,确定了在晶体中苯甲酸的分子结构,同时在计算中给出了各种频率所对应的红外强度,对光谱进行了归属。

By using multi-dimensional nuclear magnetic resonance method we have studied the folding mechanism of staphylococcal nuclease in vitro; the tertiary interactions for folding of SNase fragments into native-like conformation; the interaction between SNase N- and C-terminal subunits; the relationship of enzyme activity with folding and dynamic states of SNase; the structural properties of enzyme protein while exert its function. We have studied the internal motions of thermophilic Archaea protein Ssh10b and mechanism of its heat-resistance using the NMR 1H-15N relaxation and H/D exchange methods. We have determined the 3D solution structure of human translationally controlled tumor protein TCTP and the Ca2+-binding site; determined the 3D crystal structure of human mitoNEET, a novel protein from distinct groups of iron-sulfur proteins; determined the 3D solution structure of a novel chromatin protein Cren7. Determination of SNase-DNA and Archaea protein-DNA complex structures are in progress.

运用异核多维核磁共振方法研究了金黄色葡萄球菌酶体外折叠机制,酶蛋白片段体外折叠成类天然溶液三维构象的三级相互作用力,酶蛋白亚基间的相互作用,酶蛋白的折叠以及内运动状态与酶活力的关系,酶蛋白发挥功能时的结构特性;运用NMR的1H-15N 驰豫和H/D交换方法研究了嗜热古菌蛋白质Ssh10b双体结构内运动特性,热稳定性机制;确定了人翻译控制的肿瘤蛋白TCTP蛋白的溶液三维结构及其钙离子的结合部位;确定了一类新的铁硫蛋白家族蛋白人线粒体膜上mitoNEET蛋白的晶体结构;确定了一个新型的染色质蛋白Cren7的溶液三维结构;正在研究金黄色葡萄球菌酶及嗜热古菌蛋白质与DNA复合体的溶液三维结构。

But the conventional CoM FA exists some defects, including the selection of potential function of molecular field, the determination of bioactive conformers, the molecular alignment and the selection of variable of molecular fields, etc.

但传统的比较分子场分析方法在具体的实现过程中还存在着一些缺陷和不足,包括分子场势能函数的选择,活性构象的确定,分子的叠合以及分子场变量的选取等等。

The introduction of Ligation-Mediated PCR greatly improves the sensitivity and specificity of in vivo footprinting study, and has facilitated the executation of in vivo footprinting in the regulation of eucaryotic gene expression.

DNA相互作用的情况,而且可以检测体内的DNA构象的变化,连接介导的聚合酶链反应(Ligation-Mediated polymerase chain Reaction,LM-PCR)的发明,使得体内足迹研究的敏感性和特异性大大提高,有力地促进了体内足迹技术在真核基因表达调控研究方面的应用。

The Raman spectral bands indicated that the damage of the heating on the DNA conformation is limited below the melting point. The damage of the DNA molecular structure increased with a rise in temperature above the melting point. The damage was first obversed in adenine and deoxyribose.

研究结果表明,在熔融温度以下热处理对DNA构象的影响是轻微的,在熔融温度以上则随温度的升高,对DNA分子结构的影响及破坏也逐渐加剧,首先受影响的是腺嘌呤和脱氧核糖。

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Finally, according to market conditions and market products this article paper analyzes the trends in the development of camera technology, and designs a color night vision camera.

最后根据市场情况和市面上产品的情况分析了摄像机技术的发展趋势,并设计了一款彩色夜视摄像机。

Only person height weeds and the fierce looks stone idles were there.

只有半人深的荒草和龇牙咧嘴的神像。

This dramatic range, steeper than the Himalayas, is the upturned rim of the eastern edge of Tibet, a plateau that has risen to 5 km in response to the slow but un stoppable collision of India with Asia that began about 55 million years ago and which continues unabated today.

这一引人注目的地域范围,比喜马拉雅山更加陡峭,是处于西藏东部边缘的朝上翻的边框地带。响应启始于约5500万年前的、缓慢的但却不可阻挡的印度与亚洲地壳板块碰撞,高原已上升至五千米,这种碰撞持续至今,毫无衰退。